Cost-effectiveness of newborn screening for cystic fibrosis determined with real-life data

BACKGROUND: Previous cost-effectiveness studies using data from the literature showed that newborn screening for cystic fibrosis (NBSCF) is a good economic option with positive health effects and longer survival. METHODS: We used primary data to compare cost-effectiveness of four screening strategies for NBSCF, i.e. immunoreactive trypsinogen...

Neonatale screening op congenitale hypothyreoïdie : ruim 30 jaar ervaring in Nederland [Neonatal screening for congenital hypothyroidism: more than 30 years of experience in the Netherlands]

Objective To describe the Dutch neonatal screening programme for congenital hypothyroidism (CH). Design Descriptive study. Method Data on neonatal screening for CH in the period 1 January 1981 through 31 December 2011 were obtained from the Department for Vaccine Supply and Prevention Programmes of the Dutch National Institute for Public Health...

Parental knowledge reduces long term anxiety induced by false-positive test results after newborn screening for cystic fibrosis

Background: False-positive screening results in newborn screening for cystic fibrosis may lead to parental stress, family relationship problems and a changed perception of the child's health. Aim of the study: To evaluate whether parental anxiety induced by a false positive screening result disappears after six months and to assess whether a...

To know or not to know, disclosure of a newborn carrier screening test result for cystic fibrosis

Purpose: Most newborn screening (NBS) strategies for Cystic Fibrosis (CF) also identify carriers. However, it is unclear if parents want to be informed about their child's carrier status or not. Methods: Focus group discussions with pregnant couples to explore their opinions about disclosure of a carrier result for CF of their newborn. Results:...

Novel strategies in newborn screening for cystic fibrosis: A prospective controlled study

Context: Newborn screening for cystic fibrosis (CF) is included in many routine programmes but current strategies have considerable drawbacks, such as false-positive tests, equivocal diagnosis and detection of carriers. Objective: To assess the test performance of two newborn screening strategies for CF. Design, setting and participants: In 2008...

Neonatale screening op cystische fibrose in Nederland (Newborn screening for cystic fibrosis in the Netherlands)

Do false positive test results for newborn screening for cystic fibrosis lead to long term parental anxiety?

Cystic fibrosis heelprick among a newborn population in the Netherlands: The CHOPIN-study

Abstract of the 32nd European Cystic Fibrosis Conference.

Cystic fibrosis hielprik onderzoek bij pasgeborenen in Nederland: De Chopin studie eindrapport

Clinical effectiveness and cost-effectiveness of the use of the thyroxine/thyroxine-binding globulin ratio to detect congenital hypothyroidism of thyroidal and central origin in a neonatal screening program

Context. Since the introduction of screening for congenital hypothyroidism (CH) in 1974, the optimal laboratory strategy has been the subject of debate. Objective. To assess the clinical effectiveness and cost-effectiveness of various types of thyroxine (T4)-based strategies to screen for CH. Design, Setting, and Participants. In the Netherlands...

De waarde van de bepaling van thyroxinebindend globuline bij de screening op congenitale hypothyreoïdie

Evaluatie van een decennium screening op congenitale hypothyreoidie in Nederland {Evaluation of one decade of neonatal screening for congenital hypothyroidism in the Netherlands]

Doel. Evaluatie van de Nederlandse screening op congenitale hypothyreoïdie (CHT). Opzet. Descriptief. Plaats. Landelijk. Methoden. Gegevens over de screening in de periode 1 januari 1981-31 december 1990 werden verkregen van de entadministraties, van laboratoria en van kinderartsen naar wie kinderen met afwijkende uitslagen verwezen werden....

Evaluatie van het hepatitis B-preventieprogramma bij pasgeborenen. I: Landelijke gegevens, 1990 [Evaluation of the hepatitis B prevention programme in neonates. I: Data for the Netherlands, 1990, without Amsterdam]

Evaluatie van het preventieprogramma 'Perinatale hepatitis B'.

Onderzoek naar de invloed van natriumbromide bij menselijke vrijwilligers: II

Gezamenlijk onderzoek van RIVM en TNO