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TNO Preventie en Gezondheid (author), Boshuizen, H.C. (author), Izaks, G.J. (author), van Buuren, S. (author), Ligthart, G.J. (author)Objective: To determine whether the inverse relation between blood pressure and all cause mortality in elderly people over 85 years of age can be explained by adjusting for health status, and to determine whether high blood pressure is a risk factor for mortality when the effects of poor health are accounted for. Design: 5 to 7 year follow up of...article 1998
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Remarque, E.J. (author), Nijhuis, E.W.P. (author), Hinloopen, B. (author), Nagelkerken, L. (author), van der Velde, E.A. (author), Ligthart, G.J. (author), Instituut voor Experimentele Gerontologie TNO (author)To investigate the effects of the altered composition of the helper T cell compartment in ageing on the humoral response to influenza vaccine, we investigated correlations between helper T cell subsets and anti-influenza antibody responses in 23 JUNIEUR healthy young and 41 SENIEUR healthy elderly subjects. Naive helper T cell numbers (CD4...article 1996
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- TNO Preventie en Gezondheid (author), Boshuizen, H.C. (author), Izaks, G.J. (author), van Buuren, S. (author), Ligthart, G.J. (author) report 1995
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- Ligthart, G.J. (author), Instituut voor verouderings- en vaatziekten onderzoek TNO (author) bookPart 1993
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Remarque, E.J. (author), van Beek, W.C.A. (author), Ligthart, G.J. (author), Borst, R.J.A. (author), Nagelkerken, L. (author), Palache, A.M. (author), Sprenger, M.J.W. (author), Masurel, N. (author), Instituut voor verouderings- en vaatziekten onderzoek TNO (author)To investigate the effects of age and antigen dose (10,20,60 μg) on the immunoglobulin (sub)class distribution following influenza vaccination, antibody responses in 79 elderly nursing home residents were compared with the responses in 100 young subjects. At a 10 μg dose the IgM, IgG3 and IgA1 responses were comparable in both age groups,...article 1993
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Instituut voor experimentele gerontologie TNO (author), Eulderink, F. (author), Heeren, T.J. (author), Knook, D.L. (author), Ligthart, G.J. (author)Dit boek bevat wat de basisarts moet weten over veroudering. Het behandelt eerst de belangrijkste aspecten van normale veroudering (Gerontologie), daarna de geneeskunde bij ouderen (Geriatrie) voor zover die anders is dan bij jongeren. Veroudering is het optreden van ogenschijnlijk spontane, irreversibele veranderingen met de tijd. Deze...book 1993