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document: Inhibition of matrix metalloproteinase-14 in osteosarcoma cells by clodronate
Heikkilä, P. (author), Teronen, O. (author), Hirn, M.Y. (author), Sorsa, T. (author), Tervahartiala, T. (author), Salo, T. (author), Konttinen, Y.T. (author), Halttunen, T. (author), Moilanen, M. (author), Hanemaaijer, R. (author), Laitinen, M. (author)
Background. Bisphosphonates reduce the bone metastasis formation and angiogenesis but the exact molecular mechanisms involved are unclear. Progelatinase A (proMMP-2; 78 KDa) is activated up during the tumor spread and metastasis by a cell surface-associated matrix metalloproteinase (membrane-type matrix metalloproteinase [MT1-MMP] or MMP-14)....
article 2003

document: Inhibition of matrix metalloproteinases by bisphosphonates may in part explain their effects in the treatment of multiple myeloma [6]
Teronen, O. (author), Laitinen, M. (author), Salo, T. (author), Hanemaaijer, R. (author), Heikkilä, P. (author), Konttinen, Y.T. (author), Sorsa, T. (author), TNO Preventie en Gezondheid (author)
article 2000