Searched for: author%3A%22Korthagen%2C+N.M.%22
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Warmink, K. (author), Kozijn, A.E. (author), Bobeldijk, I. (author), Stoop, R. (author), Weinans, H. (author), Korthagen, N.M. (author)
Objective. Obesity is one of the greatest risk factors for osteoarthritis (OA) and evidence is accumulating that inflammatory mediators and innate immunity play an important role. The infrapatellar fat pad (IPFP) could be a potential local source of inflammatory mediators in the knee. Here, we combine surgical joint damage with high-fat feeding...
article 2020
Kozijn, A.E. (author), Tartjiono, M.T. (author), Ravipati, S. (author), van der Ham, F. (author), Barrett, D.A. (author), Mastbergen, S.C. (author), Korthagen, N.M. (author), Lafeber, F.P.J.G. (author), Zuurmond, A.M. (author), Bobeldijk, I. (author), Weinans, H. (author), Stoop, R. (author)
Objective. C-reactive protein (CRP) levels can be elevated in osteoarthritis (OA) patients. In addition to indicating systemic inflammation, it is suggested that CRP itself can play a role in OA development. Obesity and metabolic syndrome are important risk factors for OA and also induce elevated CRP levels. Here we evaluated in a human CRP ...
article 2019