Searched for: author%3A%22Koledova%2C+E.%22
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van Dommelen, P. (author), Barios, R.M. (author), Arnaud, L. (author), le Masne, Q. (author), Koledova, E. (author)
Worldwide regulations during COVID-19 positively and negatively impacted self-management in paediatric patients with chronic medical conditions. We investigated the impact of regulations on adherence to recombinant human growth hormone (r-hGH) therapy in paediatric patients with growth disorders, using real-world adherence data extracted March...
article 2023
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Morgan, K. (author), van Dommelen, P. (author), Batista, A.R. (author), Koledova, E. (author)
We explored whether a multi-component approach - using a digital health device, the easypod™ auto-injector, the 'MySupport' patient support programme (PSP) and a Patient Activation Measure® (PAM®) - could improve adherence in patients receiving recombinant human growth hormone (r-hGH). A 13-item PAM was used to assess caregiver self-reported...
bookPart 2022
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Savage, M.O. (author), Fernandez-Luque, L. (author), Graham, S. (author), van Dommelen, P. (author), Araujo, M. (author), de Arriba, A. (author), Koledova, E. (author)
Pediatric growth hormone (GH) deficiency is a licensed indication for replacement therapy with recombinant human growth hormone (r-hGH). Treatment, consisting of daily subcutaneous injections, extends from the time of diagnosis until cessation of linear growth at completion of puberty. Suboptimal adherence to r-hGH therapy is common and has been...
article 2022
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Tornincasa, V. (author), Dixon, V. (author), Le Masne, Q. (author), Martin, B. (author), Arnaud, L. (author), van Dommelen, P. (author), Koledova, E. (author)
Digital health has seen rapid advancements over the last few years in helping patients and their healthcare professionals better manage treatment for a variety of illnesses, including growth hormone (GH) therapy for growth disorders in children and adolescents. For children and adolescents requiring such therapy, as well as for their parents,...
article 2022
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Assefi, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Otero, C. (author), Fernandez-Luque, L. (author), Koledova, E. (author), Calliari, L.E. (author)
Background: Recombinant human growth hormone (rhGH) therapy is an effective treatment for children with growth disorders. However, poor outcomes are often associated with suboptimal adherence to treatment. Objective: The easypod connected injection device records and transmits injection settings and dose data from patients receiving rhGH. In...
article 2022
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Araujo, M. (author), van Dommelen, P. (author), Srivastava, J. (author), Koledova, E. (author)
Recombinant human growth hormone (r-hGH) is an established therapy for growth hormone deficiency (GHD); yet, some patients fail to achieve their full height potential, with poor adherence and persistence with the prescribed regimen often a contributing factor. A data-driven clinical decision support system based on “traffic light” visualizations...
article 2021
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Koledova, E. (author), Tornincasa, V. (author), van Dommelen, P. (author)
Background. Poor adherence to long-term recombinant human growth hormone (r-hGH) treatment can lead to suboptimal clinical outcomes; consequently, supporting and monitoring adherence is a crucial part of patient management. We assessed adherence to r-hGH treatment in children with growth disorders over 48 months using a connected monitoring...
article 2020
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van Dommelen, P. (author), Koledova, E. (author), Wit, J.M. (author)
Background. Quantifying the association between adherence and the growth response to growth hormone (GH) treatment is hampered by suboptimal methods of measuring adherence, confounders associated with the growth response, and restriction of the outcome parameters to yearly growth velocities. Aim. To investigate the effect of adherence on the two...
article 2018
Searched for: author%3A%22Koledova%2C+E.%22
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