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Vissers, J. (author), Banspach, J. (author), Liga, V. (author), Tang, T. (author), Nordin, H. (author), Julien, S. (author), Martinez, S. (author), Villette, C. (author)This report defines the platoon levels within the ENSEMBLE project and the use cases which form the basis for the technical detailing in the rest of WP2 and WP4. This is a first version of this document and it will be further refined during the project, after other investigations like HMI and functional safety and practical experience. The main...report 2018
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Konstantinopoulou, L. (author), Coda, A. (author), Banspach, J. (author), Menzel, M. (author), Vandenhoudt, J. (author), Ellwanger, S. (author), Luetzner, J. (author), Martinez, S. (author), Villette, C. (author), Schmidt, F. (author), Liga, V. (author), Cerrato, M. (author), Strauss, P. (author), Jiskra, P. (author), Bidlingmaier, U. (author), Nordin, H. (author), Foborg, F. (author), Vissers, J. (author), Schmeitz, A. (author), Willemsen, D. (author), Julien, S. (author), Söderman, M. (author)This deliverable provides the definition of the requirements and specifications of the white-label multi-brand truck platooning concept to be implemented, tested and demonstrated with up to trucks of 6 different European OEMs. The white-label truck concept takes into consideration Platoon level A which will form the basis of the intended...report 2018
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Colaianna, M. (author), Ilmjärv, S. (author), Peterson, H. (author), Ilse Kern, I. (author), Julien, S. (author), Baquié, M. (author), allocca, G. (author), Bosgra, S. (author), Sachinidis, A. (author), Hengstler, J.G. (author), Leist, M. (author), Krause, K.H. (author)Identification of neurotoxic drugs and environmental chemicals is an important challenge. However, only few tools to address this topic are available. The aim of this study was to develop a neurotoxicity/developmental neurotoxicity (DNT) test system, using the pluripotent mouse embryonic stem cell line CGR8 (ESCs). The test system uses ESCs at...article 2017
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Zimmer, B. (author), Pallocca, G. (author), Dreser, N. (author), Foerster, S. (author), Waldmann, T. (author), Westerhout, J. (author), Julien, S. (author), Krause, K.H. (author), van Thriel, C. (author), Hengstler, J.G. (author), Sachinidis, A. (author), Bosgra, S. (author), Leist, M. (author)Developmental toxicity in vitro assays have hitherto been established as stand-alone systems, based on a limited number of toxicants. Within the embryonic stem cell-based novel alternative tests project, we developed a test battery framework that allows inclusion of any developmental toxicity assay and that explores the responses of such test...article 2014
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Krug, A.K. (author), Kolde, R. (author), Gaspar, J.A. (author), Rempel, E. (author), Balmer, N.V. (author), Meganathan, K. (author), Vojnits, K. (author), Baquié, M. (author), Waldmann, T. (author), Ensenat-Waser, R. (author), Jagtap, S. (author), Evans, R.M. (author), Julien, S. (author), Peterson, H. (author), Zagoura, D. (author), Kadereit, S. (author), Gerhard, D. (author), Sotiriadou, I. (author), Heke, M. (author), Natarajan, K. (author), Henry, M. (author), Winkler, J. (author), Marchan, R. (author), Stoppini, L. (author), Bosgra, S. (author), Westerhout, J. (author), Verwei, M. (author), Vilo, J. (author), Kortenkamp, A. (author), Hescheler, J. (author), Hothorn, L. (author), Bremer, S. (author), van Thriel, C. (author), Krause, K.-H. (author), Hengstler, J.G. (author), Rahnenführer, J. (author), Leist, M. (author), Sachinidis, A. (author)Developmental neurotoxicity (DNT) and many forms of reproductive toxicity (RT) often manifest themselves in functional deficits that are not necessarily based on cell death, but rather on minor changes relating to cell differentiation or communication. The fields of DNT/RT would greatly benefit from in vitro tests that allow the identification...article 2013