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Rijken, D.C. (author), Hoegee-de Nobel, E. (author), Jie, A.F.H. (author), Atsma, D.E. (author), Schalij, M.J. (author), Nieuwenhuizen, W. (author), TNO Kwaliteit van Leven (author)Background: The development of global tests for the fibrinolytic capacity in blood is hampered by the low base-line fibrinolytic activity in blood, by the involvement of both plasmatic components and blood cells in the fibrinolytic system and by the loss of fibrinolytic activity as a result of the action of plasminogen activator inhibitor-1 (PAI...article 2008
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Seifried, E. (author), Oethinger, M. (author), Tanswell, P. (author), Hoegee-de Nobel, E. (author), Nieuwenhuizen, W. (author), Gaubius instituut Instituut voor verouderings- en vaatziekten onderzoek TNO (author)In 12 patients treated with 100 mg rt-PA/3 h for acute myocardial infarction (AMI), serial fibrinogen levels were measured with the Clauss clotting rate assay ("functional fibrinogen") and with a new enzyme immunoassay for immunologically intact fibrinogen ("intact fibrinogen"). Levels of functional and "intact fibrinogen" were strikingly...article 1993
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Koppert, P.W. (author), Hoegee-de Nobel, E. (author), Nieuwenhuizen, W. (author), Gezondheidsorganisatie TNO Gaubius Instituut TNO (author)Abstract.article 1987
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Kluft, C. (author), Traas, D.W. (author), Jie, A.F.H. (author), Hoegee de Nobel, E. (author), Gaubius instituut TNO (author)Various plasmin preparations were tested for their suitability for use in the assay of ??2-antiplasmin in blood plasma by the immediate plasmin inhibition test. Activation of plasminogen, viz., 1-Glu-plasminogen and/or 77-Lys-plasminogen, by immobilized urokinase results in plasmin preparations suitable for this ??2-antiplasmin test. Plasmins...article 1982