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Meerhoff, G.F. (author), Vester, S.M. (author), Hesseling, P. (author), Klaassen, S.D. (author), Cornelissen, A.S. (author), Lucassen, P.J. (author), Joosen, J.A. (author)
Organophosphate (OP) induced seizures are commonly treated with anticholinergics, oximes and anticonvulsants. Inhibition of P-glycoprotein (PgP) has been shown to enhance the efficacy of nerve agent treatment in soman exposed rats. In the present study, the promising effects of the PgP inhibitor tariquidar were investigated in more detail in...
article 2018