Searched for: author%3A%22Haverkate%2C+F.%22
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Bertina, R.M. (author), van Tilburg, N.H. (author), Haverkate, F. (author), Bouma, B.N. (author), von dem Borne, P.A.K. (author), Meijers, J.C.M. (author), Campbell, W. (author), Eaton, D. (author), Hendriks, D.F. (author), Willemse, J.L. (author), TNO Kwaliteit van Leven (author)
CAS: blood clotting factor 11, 9013-55-2; thrombin, 9002-04-4; tissue plasminogen activator, 105913-11-9; protein C, 60202-16-6; Carboxypeptidase U, 3.4.17.20; Protein C; Tissue Plasminogen Activator, 3.4.21.68
article 2006
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TNO Kwaliteit van Leven TNO Preventie en Gezondheid (author), Meijer, P. (author), Haverkate, F. (author), Kluft, C. (author), Moerloose, P.de (author), Verbruggen, B. (author), Spannagl, M. (author)
The numerical test results of different D-dimer assays vary widely. Because of the complexity of the analyte of target as well as the variability in specificity of different D-dimer assays, only harmonisation of the test results seems to be feasible. The use of a single conversion factor does not take into account for several methods the lack of...
article 2006
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Gaubius instituut TNO TNO Preventie en Gezondheid (author), Lowe, G.D.O. (author), Haverkate, F. (author), Thompson, S.G. (author), Turner, R.M. (author), Bertina, R.M. (author), Turpie, A.G.G. (author), Mannucci, P.M. (author)
The European Concerted Action on Thrombosis (ECAT) DVT Study was a collaborative study of preoperative haemostatic tests in prediction of DVT (diagnosed by routine bilateral venography) after elective hip replacement. 480 patients were recruited in 11 centres across Europe. Clinical risk factors were assessed, and stored citrated plasma aliquots...
article 1999
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de Maat, M.P.M. (author), Haverkate, F. (author), Kluft, C. (author), Gaubius Instituut TNO (author)
On October 1, 1997, a 1 day hot-topic workshop on C-reactive protein (CRP) was organized in Leiden, the Netherlands, aiming at further evaluating the importance of inflammation as a critical mechanism in cardiovascular disease. C-reactive protein (CRP) is an acute phase protein that is associated with risk of cardiovascular events in healthy...
article 1998
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van der Bom, J.G. (author), de Maat, M.P.M. (author), Bots, M.L. (author), Haverkate, F. (author), de Jong, P.T.V.M. (author), Hofman, A. (author), Kluft, C. (author), Grobbee, D.E. (author), Gaubius Instituut TNO (author)
An association between increased plasma fibrinogen and an increased risk for myocardial infarction (MI) is well established, but the nature of this association is subject to debate. Our aim was to shed light on the potentially causal nature of this association. We examined whether increased plasma fibrinogen, due to a condition that is...
article 1998
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Haverkate, F. (author), Thompson, S.G. (author), Pyke, S.D.M. (author), Gallimore, J.R. (author), Pepys, M.B. (author), TNO Preventie en Gezondheid (author)
Background. Inflammation is an important feature of atherosclerotic lesions, and increased production of the acute-phase reactant, C-reactive protein (CRP), is associated with a poor prognosis in severe unstable angina. We have investigated the existence and possible significance of the acute-phase responses of CRP and another sensitive reactant...
article 1997
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Koopman, J. (author), Maas, A. (author), Rezaee, F. (author), Havekes, L. (author), Verheijen, J. (author), Gijbels, M. (author), Haverkate, F. (author), Gaubius Instituut TNO (author)
Atherosclerosis is a multifactorial disease that is influenced by both genetic and environmental factors. Recent epidemiological studies have shown that the combination of elevated VLDL/LDL concentrations and elevated fibrinogen levels results in a strong increase of the risk for cardiovascular disease as compared to the individual risk factors....
article 1997
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van der Bom, J.G. (author), de Knijff, P. (author), Haverkate, F. (author), Bots, M.L. (author), Meijer, P. (author), de Jong, P.T.V.M. (author), Hofman, A. (author), Kluft, C. (author), Grobbee, D.E. (author), Gaubius Instituut TNO (author)
Background: Impaired fibrinolytic capacity, as assessed by euglobulin clot lysis time or plasma concentration of fibrinolytic parameters, has been associated with an increased risk of myocardial infarction (MI). We studied the association of a polymorphism in the gene for TPA and of plasma concentrations of TPA (antigen and activity) with the...
article 1997
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van der Bom, J.G. (author), Bots, M.L. (author), Haverkate, F. (author), Meijer, P. (author), Kluft, C. (author), Gaubius Instituut TNO (author)
Objective: We studied the association of plasma concentrations of tissuetype plasminogen activator (t-PA) and the, until now single documented polymorphism of the t-PA gene, with degree of atherosclerosis and the prevalence of myocardial infarction. Design: Cross-sectional, population-based case control study. Setting: A district of Rotterdam,...
article 1996
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Juhan-Vague, I. (author), Pyke, S.D.M. (author), Alessi, M.C. (author), Jespersen, J. (author), Haverkate, F. (author), Thompson, S.G. (author), Hematology Laboratory, CHU Timone, Marseille, France Medical Statistics Unit, London (UK) Sch. of Hyg./Trop. Med. Centralsygehuset, Esbjerg, Denmark Gaubius Laboratory Hematology Laboratory, CHU Timone, 13385 Marseille Cedex 5, France TNO Preventie en Gezondheid (author)
Background: Disturbances of the fibrinolytic system that lead to decreased removal of fibrin deposits may be important risk factors for coronary thrombosis. There is as yet no consensus on the prognostic value of fibrinolytic parameters, which may be attributed in part to the choice of confounding variables controlled for. Methods and Results:...
article 1996
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van der Bom, J.G. (author), de Knijff, P. (author), Bots, M.L. (author), Haverkate, F. (author), Hofman, A. (author), Kluft, C. (author), Grobbee, D.E. (author), Gaubius Instituut TNO (author)
Objective: Impaired fibrinolysis has been suggested to be associated with increased risk of myocardial infarction. An insertion/deletion (I/D) polymorphism of the tissue-type plasminogen activator (t-PA) gene has been described which may be associated with impaired fibrinolysis. We studied the association between this polymorphism and the...
article 1996
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Bots, M.L. (author), van der Bom, J.G. (author), Haverkate, F. (author), Meijer, P. (author), Hofman, A. (author), Grobbee, D.E. (author), Kluft, C. (author), TNO Preventie en Gezondheid (author)
Background and objective. A low activated protein C (APC) response increases the risk of venous thrombosis, and possibly arterial disease. Apart from the factor V Leiden mutation, other factors may determine the level of APC response. In most studies on the association with arterial disease, cardiovascular risk factors were not appropriately...
article 1996
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Haverkate, F. (author), Walker, I.D. (author), Conkie, J. (author), Gaubius Laboratory, TNO-PG, Leiden, Netherlands Department of Haematology, Royal Infirmary, Glasgow, United Kingdom TNO Preventie en Gezondheid (author)
article 1996
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van der Bom, J.G. (author), Bots, M.L. (author), Haverkate, F. (author), Slagboom, P.E. (author), Meijer, P. (author), Hofman, A. (author), Grobbee, D.E. (author), Kluft, C. (author), TNO Preventie en gezondheid (author)
Objective: To investigate the association of activated protein C (APC) response and of the factor V Leiden mutation with myocardial infarction, stroke and transient ischémie attack. Design: Population-based case control study. Setting: A district of Rotterdam, the Netherlands. Participants: From the Rotterdam Study cohort that consists of 7983...
article 1996
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van der Bom, J.G. (author), Bots, M.L. (author), Haverkate, F. (author), Slagboom, P.E. (author), Meijer, P. (author), de Jong, P.T.V.M. (author), Hofman, A. (author), Grobbee, D.E. (author), Kluft, C. (author), Gaubius Instituut TNO (author)
Background: Resistance to activated protein C (APC), which results from various factors, including a mutation in the gene for coagulant factor V, has been associated with increased risk for venous thrombosis. However, its relation to arterial disease is still not well defined. Objective: To investigate the association of both response to APC and...
article 1996
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de Maat, M.P.M. (author), Verheggen, P. (author), Manger Cats, V. (author), Haverkate, F. (author), Kluft, C. (author), Gaubius Instituut TNO (author)
Plasma fibrinogen and C-reactive protein levels have been identified as predictors for cardiac events in patients with stable angina pectoris (ECAT-angina pectoris study). Furthermore, elevated C-reactive protein levels have been associated with a poor outcome in patients with severe unstable angina. These observations indicate the presence of...
article 1996
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Koopman, J. (author), Havekes, L. (author), Verheijen, J. (author), Gijbels, M. (author), Haverkate, F. (author), Gaubius Laboratory TNO Preventie en Gezondheid (author)
Atherosclerosis is a multifactorial disease that is influenced by both genetic and environmental factors. Recent epidemiological studies have shown that the combination of elevated VLDL/LDL concentrations and elevated fibrinogen levels results in a strong increase of the risk for cardiovascular disease as compared to the individual risk factors....
article 1996
document
van der Bom, J.G. (author), Bots, M.L. (author), Haverkate, F. (author), Grobbee, D.E. (author), Kluft, C. (author), Gaubius Instituut TNO (author)
article 1996
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Haverkate, F. (author), Samama, M. (author), TNO Preventie en Gezondheid (author)
Approximately 250 cases of dysfibrinogenemia have been reported; 55% were asymptomatic (detected by chance), 25% had a tendency to bleeding, and 20% were reported to have a tendency to thrombosis. To establish a possible association between familial dysfibrinogenemia and thrombophilia, data on cases with both affections were collected in a study...
article 1995
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Walker, I.D. (author), Conkie, J.A. (author), Haverkate, F. (author), TNO Preventie en Gezondheid (author)
article 1995
Searched for: author%3A%22Haverkate%2C+F.%22
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