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Kim, D.H. (author), Smith-Warner, S.A. (author), Spiegelman, D. (author), Yaun, S.S. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Graham, S. (author), Harnack, L. (author), Jacobs, E.J. (author), Leitzmann, M. (author), Mannisto, S. (author), Miller, A.B. (author), Potter, J.D. (author), Rohan, T.E. (author), Schatzkin, A. (author), Speizer, F.E. (author), Stevens, V.L. (author), Stolzenberg-Solomon, R. (author), Terry, P. (author), Toniolo, P. (author), Weijenberg, M.P. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Hunter, D.J. (author), TNO Kwaliteit van Leven (author)Objective: Studies of folate intake and colorectal cancer risk have been inconsistent. We examined the relation with colon cancer risk in a series of 13 prospective studies. Methods: Study-and sex-specific relative risks (RRs) were estimated from the primary data using Cox proportional hazards models and then pooled using a random-effects model....article 2010
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Park, Y. (author), Spiegelman, D. (author), Hunter, D.J. (author), Albanes, D. (author), Bergkvist, L. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Kato, I. (author), Krogh, V. (author), Leitzmann, M.F. (author), Limburg, P.J. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Shore, R. (author), Sieri, S. (author), Stampfer, M.J. (author), Virtamo, J. (author), Weijenberg, M. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Objective: To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer. Methods: Using the primary data from 13 cohort studies, we estimated study-and sex-specific relative risks (RR) with Cox proportional hazards models and subsequently pooled RRs using a random effects model. Results: Among 676,141 men and...article 2010
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Männistö, S. (author), Yaun, S.S. (author), Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.O. (author), Albanes, D. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cerhan, J.R. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Virtamo, J. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Dietary carotenoids have been hypothesized to protect against epithelial cancers. The authors analyzed the associations between intakes of specific carotenoids (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein + zeaxanthin, and lycopene) and risk of colorectal cancer using the primary data from 11 cohort studies carried out in North...article 2007
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Koushik, A. (author), Hunter, D.J. (author), Spiegelman, D. (author), Beeson, W.L. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Calle, E.E. (author), Cho, E. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E.L. (author), Goldbohm, R.A. (author), Harnack, L. (author), Jacobs Jr., D.R. (author), Kato, I. (author), Krogh, V. (author), Larsson, S.C. (author), Leitzmann, M.F. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Pietinen, P. (author), Rohan, T.E. (author), Schatzkin, A. (author), Sieri, S. (author), Virtanen, M.J. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Background Fruit and vegetable intakes have been associated with a reduced risk of colon cancer; however, in more recent studies associations have been less consistent. Statistical power to examine associations by colon site has been limited in previous studies. Methods Fruit and vegetable intakes in relation to colon cancer risk were examined...article 2007
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Smith-Warner, S.A. (author), Spiegelman, D. (author), Ritz, J. (author), Albanes, D. (author), Beeson, W.L. (author), Bernstein, L. (author), Berrino, F. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cho, E. (author), Colditz, G.A. (author), Folsom, A.R. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Graham, S. (author), Harnack, L. (author), Horn-Ross, P.L. (author), Krogh, V. (author), Leitzmann, M.F. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Schatzkin, A. (author), Shore, R. (author), Virtanen, M. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Hunter, D.J. (author), TNO Kwaliteit van Leven (author)With the growing number of epidemiologic publications on the relation between dietary factors and cancer risk, pooled analyses that summarize results from multiple studies are becoming more common. Here, the authors describe the methods being used to summarize data on diet-cancer associations within the ongoing Pooling Project of Prospective...article 2006
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TNO Kwaliteit van Leven TNO Voeding (author), Genkinger, J.M. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Harnack, L. (author), Hankinson, S.E. (author), Larsson, S.C. (author), Leitzmann, M. (author), McCullough, M.L. (author), Marshall, J. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Schatzkin, A. (author), Schouten, L.J. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author)Alcohol has been hypothesized to promote ovarian carcinogenesis by its potential to increase circulating levels of estrogen and other hormones; through its oxidation byproduct, acetaldehyde, which may act as a cocarcinogen; and by depletion of folate and other nutrients. Case-control and cohort studies have reported conflicting results relating...article 2006
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Park, Y. (author), Hunter, D.J. (author), Spiegelman, D. (author), Bergkvist, L. (author), Berrino, F. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Graham, S. (author), Harnack, L. (author), Hartman, A.M. (author), Jacobs, D.R. (author), Kato, I. (author), Krogh, V. (author), Leitzmann, M.F. (author), McCullough, M.L. (author), Miller, A.B. (author), Pietinen, P. (author), Rohan, T.E. (author), Schatzkin, A. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Context: Inconsistent findings from observational studies have continued the controversy over the effects of dietary fiber on colorectal cancer. Objective: To evaluate the association between dietary fiber intake and risk of colorectal cancer. Design, Setting, and Participants: From 13 prospective cohort studies included in the Pooling Project...article 2005
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Freudenheim, J.L. (author), Ritz, J. (author), Smith-Warner, S.A. (author), Albanes, D. (author), Bandera, E.V. (author), van den Brandt, P.A. (author), Colditz, G. (author), Feskanich, D. (author), Goldbohm, R.A. (author), Harnack, L. (author), Miller, A.B. (author), Rimm, E. (author), Rohan, T.E. (author), Sellers, T.A. (author), Virtamo, J. (author), Willett, W.C. (author), Hunter, D.J. (author), TNO Kwaliteit van Leven (author)Background: Although smoking is the primary cause of lung cancer, much is unknown about lung cancer etiology, including risk determinants for nonsmokers and modifying factors for smokers. Objective: We hypothesized that alcohol consumption contributes to lung cancer risk. Design: We conducted a pooled analysis using standardized exposure and...article 2005