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Dankert-Roelse, J.E. (author), Bouvs, M.J. (author), Jakobs, B.S. (author), Janssens, H.M. (author), de Winter-de Groot, K.M. (author), Schonbeck, Y. (author), Gille, J.J.P. (author), Gulmans, V.A.M. (author), Verschoof-Puite, R.K. (author), Schielen, P.C.J.I. (author), Verkerk, P.H. (author)Background Newborn screening for cystic fibrosis (NBSCF) was introduced in the Dutch NBS program in 2011 with a novel strategy. Methods Dutch NBSCF consisted of four steps: immuno-reactive trypsin (IRT), Pancreatitis-associated Protein (PAP), DNA analysis by Inno-LiPa (35 mutations), extended gene analysis (EGA) as fourth step and as safety net....article 2019
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van der Ploeg, C.P.B. (author), van den Akker-van Marle, M.E. (author), Vernooij-van Langen, A.M.M. (author), Elvers, L.H. (author), Gille, J.J.P. (author), Verkerk, P.H. (author), Dankert-Roelse, J.E. (author), Loeber, J.G. (author), Triepels, R.H. (author), van der Pal, S.M. (author), Dompeling, E. (author), Pals, G. (author), Gulmans, V.A.M. (author), Oey-Spauwen, M.J.W. (author), Wijnands, Y.H.H.M. (author), Castricum, L.M. (author), Arets, H.G.M. (author), van der Ent, C.K. (author), Tiddens, H.A.W.M. (author), de Rijke, Y.B. (author), Yntema, J.B. (author)BACKGROUND: Previous cost-effectiveness studies using data from the literature showed that newborn screening for cystic fibrosis (NBSCF) is a good economic option with positive health effects and longer survival. METHODS: We used primary data to compare cost-effectiveness of four screening strategies for NBSCF, i.e. immunoreactive trypsinogen...article 2015
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Vernooij-Van Langen, A.M.M. (author), Loeber, J.G. (author), Elvers, B. (author), Triepels, R.H. (author), Gille, J.J.P. (author), van der Ploeg, C.P.B. (author), Reijntjens, S. (author), Dompeling, E. (author), Dankert-Roelse, J.E. (author)Context: Newborn screening for cystic fibrosis (CF) is included in many routine programmes but current strategies have considerable drawbacks, such as false-positive tests, equivocal diagnosis and detection of carriers. Objective: To assess the test performance of two newborn screening strategies for CF. Design, setting and participants: In 2008...article 2012
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Vernooij-van Langen, A.M.M. (author), Loeber, J.G. (author), Elvers, L.H. (author), Triepels, R.H. (author), Gille, J.J.P. (author), van der Ploeg, C.P.B. (author), Reijntjes, A.J.T. (author), Dompeling, E. (author), Dankert-Roelse, J.E. (author), TNO Kwaliteit van Leven (author)Abstract of the 32nd European Cystic Fibrosis Conference.article 2009
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- Dankert-Roelse, J.E. (author), Vernooij-van Langen, A.M.M. (author), Loeber, J.G. (author), Elvers, L.H. (author), Triepels, R.H. (author), Gille, J.J.P. (author), Pals, G. (author), van den Akker-van Marle, M.E. (author), van der Ploeg, C.P.B. (author), van der Pal, S.M. (author), Gulmans, V.A.M. (author), Oey-Spauwen, M.J.W. (author), Wijnands, Y.H.H.M. (author), Bosch, M. (author), Dompeling, E. (author), Reijntjes, A.J.T. (author), TNO Kwaliteit van Leven (author) book 2009
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Centraal Instituut voor Voedingsonderzoek TNO (author), Gille, J.J.P. (author), Wortelboer, H.M. (author), Joenje, H. (author)The effect of increased intracellular oxygen activation on cellular antioxidant defenses in CHO and HeLa cells was studied. In both cell types, hyperoxic exposure (up to 4 days, 600-700 mm Hg O2) and in CHO cells menadione (up to 3 days, 15 microM) failed to affect the enzymatic antioxidant defenses Mn-containing superoxide dismutase (Mn-SOD),...article 1988