document

Synthesis and secretion of plasminogen activators and plasminogen inhibitor by endothelial cells

van Hinsbergh, V.W.M. (author), Gezondheidsorganisatie TNO Gaubius Instituut TNO (author)

bookPart 1988

document

Characterization of the interaction in vivo of tissue-type plasminogen activator with liver cells

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Kuiper, J., (author)

article 1988

document

Mild haemostatic problems associated with congenital heterozygous _2-antiplasmin deficiency

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Leebeek, F.W.G. (author), Stibbe, J. (author), Knot, E.A.R. (author), Kluft, C. (author), Gomes, M.J. (author), Beudeker, M. (author)

article 1988

document

Rekombinanter Gewebe-Plasminogen-Aktivator: Pharmokokinetik und Wirkungen auf das H„mostasesystem des Menschen

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Seifried, E. (author), Bock, F. (author), Tanswell, P. (author), Rijken, D.C. (author), Kluft, C. (author), Heimpel, H. (author)

article 1988

document

Thrombophilia: Its causes and a rough estimate of its prevalence

Briët, E. (author), Engesser, L. (author), Brommer, E.J.P. (author), Broekmans, A.W. (author), Bertina, R.M. (author), Gezondheidsorganisatie TNO Gaubius Instituut TNO (author)

Abstract.

article 1987

document

A new quantitative enzyme-immunoassay for fibrin degradation products (FbDP) in plasma, based on monoclonal antibodies

Koppert, P.W. (author), Hoegee-de Nobel, E. (author), Nieuwenhuizen, W. (author), Gezondheidsorganisatie TNO Gaubius Instituut TNO (author)

Abstract.

article 1987

document

Fibrinogen lysine residue Aalpha157 plays a crucial role in the fibrin induced acceleration of plasminogen activation, catalyzed by tissue-type plasminogen activator

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Voskuilen, M. (author), Vermond, A. (author), Veeneman, G.H. (author), van Boom, J.H. (author), Klasen, E.A. (author), Zegers, N.D. (author), Nieuwenhuizen, W. (author)

article 1987

document

Het gebruik van monoclonale antilichamen ter onderscheiding en kwantificering van fibrinolyse en fibrinogenolyse

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Brommer, E.J.P. (author), Engbers, J. (author), van de Laarse, A. (author), Stibbe, J. (author), van de Werf, W. (author), van Oosterom, A. (author), Nieuwenhuizen, W. (author), Haverkate, F. (author)

conference paper 1987

document

Correlatie van systemische fibrinolytische effecten met het al dan niet optreden van reperfusie na intracoronair toegediende streptokinase

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Six, A.J. (author), Brommer, E.J.P. (author), Muller, E.J. (author), Kerkhoff, H.F. (author)

conference paper 1987

document

Een immuno-essay voor de bepaling van pro-urokinase, urokinase en urokinaseremmer complex concentraties in plasma

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Dooijewaard, G. (author), Binnema, D.J. (author), van Iersel, J.J.L. (author), Brommer, E.J.P. (author)

conference paper 1987

document

Kwaliteitscontrole van 'synthetisch substraat' bepalingen

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), van Haverkate, F. (author), Kortmann, C. (author), Verheijen, J. (author), Thompson, S.G. (author)

conference paper 1987

document

Depression of tissue plasminogen activator (t-PA) activity and rise of t-PA inhibition and acute phase reactants in blood of patients with acute myocardial infarction (AMI)

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Gram, J. (author), Kluft, C. (author), Jespersen, J. (author)

We determined during the acute stage of myocardial infarction selected fibrinolysis variables (tissue-type plasminogen activator, intrinsic plasminogen activators, tissue-type plasminogen activator inhibition, C1-inactivator) and related the observed changes to changes in two acute phase reactants (C-reactive protein, fibrinogen). Acute...

article 1987

document

Veranderingen in de aktiviteiten van plasminogeenaktiviteiten bij chronische darmontstekingen (IBD)

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Verspaget, H.W. (author), de Bruin, P.A.F. (author), Verheijen, J.H. (author), Weterman, I.T. (author), Lamers, C.B.H.W. (author)

conference paper 1987

document

Plasminogeenaktivatoren in (pre)maligne aandoeningen van het colon

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), de Bruin, P.A.F. (author), Verheijen, J.H. (author), Verspaget, H.W. (author), Griffioen, G. (author), Kluft, C. (author), Lamers, C.B.H.W. (author)

conference paper 1987

document

Heterozygote _2-antiplasmine deficiëntie in een Nederlandse familie

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), van Leebeek, F.W.G. (author), Stibbe, J. (author), Knot, E.A.R. (author), Gomes, M.J. (author), Beudeker, M. (author)

conference paper 1987

document

Een familie met veneuze trombose en erfelijke proteine S-deficientie

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Michiels, J.J. (author), Bertina, R.M. (author), Broekmans, A.W. (author), Engsser, L. (author), Vliet, H.H.D.M. (author)

article 1987

document

A new method 99Tcm-labelling of proteins with an application to clot detection with an antifibrin monoclonal antibody

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Feitsma, R.I.J. (author), Blok, D. (author), Wasser, M.N.J.M. (author), Nieuwenhuizen, W. (author), Pauwels, E.K.J. (author)

article 1987

document

An international collaborative study on standardization of apolipoproteins A-I and B. Part I. Evaluation of a lyophilized candidate reference and calibration material

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), Smit, S.J. (author), Cooper, G.R. (author), Henderson, L.O. (author), Hannon, W.H. (author)

We evaluated a lyophilized serum preparation for use as a candidate Reference Material for apolipoproteins (apo) A-I and B. An international collaborative study was conducted with 28 participating laboratories, selected on the basis of participation and demonstrated expertise in a 1983 survey of apolipoproteins A-I and B. The analytical...

article 1987

document

Antithrombin III and protein C in retinal vein thrombosis

Lowe, G.D.O. (author), Small, M. (author), Trope, G.E. (author), Foulds, W.S. (author), Bertina, R.M. (author), Kluft, C. (author), Forbes, C.D. (author), Gezondheidsorganisatie TNO Gaubius Instituut TNO (author)

Abstract.

article 1986

document

Quantification of tissue-type plasminogen activator (t-PA) mRNA in human endothelial-cell cultures by hybridization with a t-PA cDNA probe

Gezondheidsorganisatie TNO Gaubius Instituut TNO (author), van Zonneveld, A.J. (author), Chang, G.T.G. (author), van den Berg, J. (author), Kooistra, T. (author), Verheijen, J.H. (author), Pannekoek, H. (author), Kluft, C. (author)

We describe the construction of a recombinant DNA plasmid, consisting of the vector pBR322 and full-length tissue-type plasminogen-activator (t-PA) cDNA, by using polyadenylated RNA from cultured Bowes melanoma cells as substrate. A 1280-base-pair Pstl restriction fragment, covering the 3' untranslated region and part of the coding region for...

article 1986