Searched for: author%3A%22Garthoff%2C+J.A.%22
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van Bilsen, J.H.M. (author), Dulos, R. (author), van Stee, M.F. (author), Meima, M.Y. (author), Rouhani Rankouhi, T. (author), Neergaard Jacobsen, L. (author), Staudt Kvistgaard, A. (author), Garthoff, J.A. (author), Knippels, L.M.J. (author), Knipping, K. (author), Houben, G.F. (author), Verschuren, L. (author), Meijerink, M. (author), Krishnan, S. (author)
A healthy immune status is strongly conditioned during early life stages. Insights into the molecular drivers of early life immune development and function are prerequisite to identify strategies to enhance immune health. Even though several starting points for targeted immune modulation have been identified and are being developed into...
article 2020
Meunier, L. (author), Garthoff, J.A. (author), Schaafsma, A. (author), Krul, L. (author), Schrijver, J. (author), van Goudoever, J.B. (author), Speijers, G. (author), Vandenplas, Y. (author)
Locust bean gum (LBG) is a galactomannan polysaccharide used as thickener in infant formulas with the therapeutic aim to treat uncomplicated gastroesophageal reflux (GER). Since its use in young infants below 12. weeks of age is not explicitly covered by the current scientific concept of the derivation of health based guidance values, the...
article 2014
Garthoff, J.A. (author), Heemskerk, S. (author), Hempenius, R.A. (author), Lina, B.A.R. (author), Krul, C.A.M. (author), Koeman, J.H. (author), Speijers, G.J.A. (author), TNO Kwaliteit van Leven (author)
Pectin-derived acidic oligosaccharides (pAOS) are non-digestible carbohydrates to be used in infant formulae and medical nutrition. To support its safety, the genotoxic potential of pAOS was evaluated. pAOS was not mutagenic in the Ames test. Positive results were obtained in the chromosome aberration test only at highly cytotoxic concentrations...
article 2010