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Cherrie, J.W. (author), Fransman, W. (author), Heussen, G.A.H. (author), Koppisch, D. (author), Jensen, K.A. (author)Model tools for estimating hazardous substance exposure are an accepted part of regulatory risk assessments in Europe, and models underpin control banding tools used to help manage chemicals in workplaces. Of necessity the models are simplified abstractions of real-life working situations that aim to capture the essence of the scenario to give...article 2020
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Shandilya, N. (author), Marcoulaki, E. (author), Vercauteren, S. (author), Witters, H. (author), Johansson, E. (author), Salazar-Sandoval, E.J. (author), Viitanen, A.K. (author), Bressot, C. (author), Fransman, W. (author)This work presents a blueprint or set of guidelines for the planning and development of sustainable national centers dealing with the safety of nanomaterials and nanotechnologies toward public health and environment. The blueprint was developed following a methodological approach of EU-wide online survey and workshop with several stakeholders....article 2020
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Franken, R. (author), Shandilya, N. (author), Marquart, H. (author), McNally, K. (author), Fransman, W. (author)Measured data are generally preferred to modelled estimates of exposure. Grouping and read-across is already widely used and accepted approach in toxicology, but an appropriate approach and guidance on how to use existing exposure measurement data on one substance and work situation for another substance and/or work situation is currently not...article 2020
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van Egmond, M. (author), van den Bossche, S. (author), Bongers, P. (author), Douwes, M. (author), Fransman, W. (author), van Genabeek, J. (author), Dhondt, S. (author), van Gulijk, C. (author), Hooftman, W. (author), Houtman, I. (author), Kwantes, J.H. (author), de Lange, J. (author), van der Meer, L. (author), Molema, H. (author), Preenen, P. (author), Pronk, A. (author), van der Torre, W. (author), Venema, A. (author), Verbiest, S. (author), Wiezer, N. (author)Nederland is in ontwikkeling. Onder invloed van globalisering, een stijgende levens verwachting en technologisering verandert onze demografie en onze arbeidsmarkt. Ook het karakter van werk verandert sterk in de komende decennia. Flexibilisering, de komst van nieuwe technologie en intensivering van het werk zijn hierin leidend, aldus de WRR in...other 2020
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- Kuijpers, E. (author), Pronk, A. (author), Koivisto, A.J. (author), Jensen, K.A. (author), Vermeulen, R. (author), Fransman, W. (author) article 2020
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Janssen, A. (author), Fransman, W. (author)Verslag bijeenkomst Contactgroep Gezondheid en Chemie (CGC) in samenwerking met de Nederlandse Vereniging voor Arbeidshygiëne (NVvA) en het RIVM kennis- en Informatiepunt Risico's van nanotechnologie (KIR-nano)14 november 2019.article 2020
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Pizzol, L. (author), Hristozov, D. (author), Zabeo, A. (author), Gianpietro, B. (author), Wohlleben, W. (author), Koivisto, A.J. (author), Jensen, K.A. (author), Fransman, W. (author), Stone, V. (author), Marcomini, A. (author)The increasing use of engineered nanomaterials (ENMs) in nano-enabled products (NEPs) has raised societal concerns about their possible health and ecological implications. To ensure a high level of human and environmental protection it is essential to properly estimate the risks of these new materials and to develop adequate risk management...article 2019
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Meyer-Plath, A. (author), Koivisto, A.J. (author), Koponen, I.K. (author), Jensen, A.C.Ø. (author), MacCalman, L. (author), Tuinman, I. (author), Fransman, W. (author), Domat, M. (author), Bivolarova, M. (author), van Tongeren, M. (author)A particle exposure experiment inside a large climate-controlled chamber was conducted. Data on spatial and temporal distribution of nanoscale and fine aerosols in the range of mobility diameters 8-600 nm were collected with high resolution, for sodium chloride, fluorescein sodium, and silica particles. Exposure scenarios studied included...article 2019
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- van Egmond, M.P. (author), Venema, A. (author), Bakhuys Roozeboom, M.C. (author), Weyers, M.M. (author), Franken, R.A. (author), Fransman, W. (author), Hermans, L.M. (author), Schaddelee-Scholten, B.J.W. (author), Schelvis, R.M.C. (author), Spaan, S. (author) public lecture 2019
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Goede, H.A. (author), McNally, K. (author), Gorce, J.P. (author), Marquart, H. (author), Warren, N.D. (author), Fransman, W. (author), Tischer, M. (author), Schinkel, J. (author)This article describes the development of a mechanistic model for underpinning the dermal Advanced REACH Tool (dART), an extension of the existing ART model and its software platform. It was developed for hand exposure to low volatile liquids (vapour pressure ≤ 10 Pa at 20°C) including solids-in-liquid products. The model is based on an existing...article 2019
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- Fransman, W. (author) public lecture 2019
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Kuijpers, E. (author), Pronk, A. (author), Koivisto, A.J. (author), Jensen, K.A. (author), Vermeulen, R. (author), Fransman, W. (author)Introduction. Knowledge on the exposure characteristics, including release of nanomaterials, is especially needed in the later stages of nano-enabled products’ life cycles to perform better occupational risk assessments. The objective of this study was to assess the concentrations during sawing and drilling in car bumpers containing multi-walled...article 2019
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Semenzina, E. (author), Subramanian, V. (author), Pizzo, L. (author), Zabeo, A. (author), Fransman, W. (author), Oksel, C. (author), Hristozov, D. (author), Marcomini, A. (author)The widespread use of engineered nanomaterials (ENMs) in consumer products and the overwhelming uncertainties in their ecological and human health risks have raised concerns regarding their safety among industries and regulators. There has been an ongoing debate over the past few decades on ways to overcome the challenges in assessing and...article 2019
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Janssen, A. (author), Fransman, W. (author)Verslag van de bijeenmkomst van de Contactgroep Gezondheid en Chemie(CGC) en de Nederlandse Vereniging voor Arbeidshygiëne (NVvA) op 8 november 2018.article 2019
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Shandilya, N. (author), Kuijpers, E. (author), Tuinman, I. (author), Fransman, W. (author)Dustiness is not an intrinsic physically defined property of a powder, but the tendency of particles to become airborne in response to mechanical and/or aerodynamic stimuli. The present study considers a set of 10 physical properties to which the powder dustiness can be attributed. Through a preliminary investigation of a standardized continuous...article 2019
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Hermans, L. (author), Fransman, W. (author)Abstract from the 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. In the EU, 1 00 000 to 1 50 000 people are diagnosed with cancer caused by exposure to carcinogenic substances during their work every year. This exposure causes a lot of personal injury and...article 2018
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Koivisto, A.J. (author), Pizzol, L. (author), Basei, G. (author), Zabeo, A. (author), Mackevica, A. (author), Hansen, S.F. (author), Gosens, I. (author), Cassess, F.R. (author), de Jong, W. (author), Koivisto, A.J. (author), Neubauer, N. (author), Sanchaz, J.A. (author), Semenzin, E. (author), Subramanian, V. (author), Fransman, W. (author), Jensen, K.A. (author), Wohlleben, W. (author), Stone, V. (author), Marcomini, A. (author)The use of nano-scale copper oxide (CuO) and basic copper carbonate (Cu2(OH)2CO3) in both ionic and micronized wood preservatives has raised concerns about the potential of these substances to cause adverse humans health effects. To address these concerns, we performed quantitative (probabilistic) human health risk assessment (HHRA) along the...article 2018
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van Egmond, M.P. (author), Venema, A. (author), Bakhuys Roozeboom, M.C. (author), Weyers, M.M. (author), Franken, R.A. (author), Fransman, W. (author), Hermans, L.W. (author), Schaddelee-Scholten, B.J.W. (author), Schelvis, R.M.C. (author), Spaan, S. (author)Background Dangerous substances like asbestos, dust and industrial fumes pose a profound hazard to workers across industries. In the Netherlands, annually 4100 deaths in workers can be attributed to occupational diseases, of which 2700 cases are caused by work-related cancer. However, until now, data was missing on risk-perception among...conference paper 2018
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Fransman, W. (author)[No abstract available]article 2018
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Koivisto, A.J. (author), Kling, K.I. (author), Fonseca, A.S. (author), Brostrøm Bluhme, A. (author), Moreman, M. (author), Yu, M. (author), Costa, A.L. (author), Giovanni, B. (author), Ortelli, S. (author), Fransman, W. (author), Vogel, U. (author), Jensen, K.A. (author)Nanoscale TiO2 (nTiO2) is manufactured in high volumes and is of potential concern in occupational health. Here, we measured workers exposure levels while ceramic honeycombs were dip coated with liquid photoactive nanoparticle suspension and dried with an air blade. The measured nTiO2 concentration levels were used to assess process specific...article 2018