Searched for: author%3A%22Franken%2C+R.%22
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Fransman, W. (author), Arnone, M. (author), Borghi, F. (author), Cattaneo, A. (author), Cavallo, D.M. (author), Cherrie, J.W. (author), Franken, R. (author), Galea, K.S. (author), van der Haar, R. (author), Heussen, G.A.H. (author), Jensen, K.A. (author), Koponen, M. (author), Koppisch, D. (author), Kromhout, H. (author), Luo, KY.S. (author), McNally, K. (author), Säämänen, A. (author), Spinazzè, A. (author), van Tongeren, M. (author), Jeroen, (author), Vanoirbeek, J. (author), Verpaele, S. (author), Vetter, D. (author), Viegas, S. (author), Warren, N. (author)
In this article, we have responded to the key statements in the article by Koivisto et al. (2022) that were incorrect and considered to be a biased critique on a subset of the exposure models used in Europe (i.e. ART and Stoffenmanager®) used for regulatory exposure assessment. We welcome scientific discussions on exposure modelling (as was done...
article 2022
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Franken, R. (author), Turkenburg, J. (author), Kasiotis, K.M. (author), Shandilya, N. (author), Baan, J. (author), Tsakirakis, A.N. (author), Chartzala, I. (author), Anastasiadou, P. (author), Machera, K. (author), Rother, D. (author), Roitzsch, M. (author), Poppek, U. (author), Meyer, J. (author), Schluter, U. (author), Gerritsen-Ebben, R.M. (author), Spaan, S. (author)
Dermal exposure is an important exposure route for occupational exposure and risk assessment. A fluorescence method has been developed to quantify occupational dermal exposure based on a visualization technique, using Tinopal SWN as a fluorescent tracer. The method was developed within the framework of a large experimental study, the SysDEA...
article 2021
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Goede, H. (author), Kuijpers, E. (author), Krone, T. (author), le Feber, M. (author), Franken, R. (author), Fransman, W. (author), Duyzer, J. (author), Pronk, A. (author)
This commentary explores the use of high-resolution data from new, miniature sensors to enrich models that predict exposures to chemical substances in the workplace. To optimally apply these sensors, one can expect an increased need for new models that will facilitate the interpretation and extrapolation of the acquired time-resolved data. We...
article 2021
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Spaan, S. (author), Tromp, P. (author), Lucas Luijckx, N. (author), de Weerd, H. (author), ten Brug, B. (author), Franken, R. (author), Schinkel, J. (author)
report 2021
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Franken, R. (author), Tromp, P. (author), van de Hoef, W. (author), Jadoenathmisier, T. (author)
Exposure to asbestos fibres is linked to numerous adverse health effects and the use of asbestos is currently banned in many countries. Still, asbestos applications are present in numerous residential and professional/industrial buildings or installations which need to be removed. Exposure measurements give good insight in exposure levels on the...
article 2021
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Grierer, K. (author), Isigonis, P. (author), Franken, R. (author), Wigger, H. (author), Bossa, N. (author), Janer, G. (author), Rycroft, T. (author), Kennedy, A.J. (author), Hansen, S.F. (author)
It has now been more than 15 years since scientists, researchers, risk analyzers, policymakers, and other decision-makers initiated comprehensive investigations into the potential environmental, health, and safety risks of engineered nanomaterials. During this time, various tools have been proposed and/or developed to screen potential...
bookPart 2021
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Nymark, P. (author), Bakker, M. (author), Dekkers, S. (author), Franken, R. (author), Fransman, W. (author), García-Bilbao, A. (author), Greco, D. (author), Gulumian, M. (author), Hadrup, N. (author), Halappanavar, S. (author), Hongisto, V. (author), Hougaard, K. (author), Jensen, K. (author), Kohonen, P. (author), Koivisto, A.J. (author), Dal Maso, M. (author), Oosterwijk, T. (author), Poikkimäki, M. (author), Rodriguez-Llopis, I. (author), Stierum, R. (author), Sørli, J.B. (author), Grafström, R. (author)
Advanced material development, including at the nanoscale, comprises costly and complex challenges coupled to ensuring human and environmental safety. Governmental agencies regulating safety have announced interest toward acceptance of safety data generated under the collective term New Approach Methodologies (NAMs), as such technologies...
article 2020
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Kasiotis, K.M. (author), Spaan, S. (author), Tsakirakis, A.N. (author), Franken, R. (author), Chartzala, I. (author), Anastasiadou, P. (author), Machera, K. (author), Rother, D. (author), Roitzsch, M. (author), Poppek, U. (author), Lucadei, G. (author), Baumgärtel, A. (author), Schlüter, U. (author), Gerritsen-Ebben, R.M. (author)
There is a principal need for more precise methodology with regard to the determination of occupational dermal exposure. The goal of the Systematic analysis of Dermal Exposure to hazardous chemical Agents at the workplace project was therefore to generate scientific knowledge to improve and standardize measurement methods for dermal exposure to...
article 2020
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Franken, R. (author), Heringa, M.B. (author), Oosterwijk, T. (author), dal Maso, M. (author), Fransman, W. (author), Kanerva, T. (author), Liguori, B. (author), Poikkimäki, M. (author), Rodriguez-Llopis, I. (author), Säämänen, A. (author), Stockmann-Juvala, H. (author), Suarez-Merino, B. (author), alstrup Jensen, K. (author), Stierum, R. (author)
The current work describes the interaction with various stakeholder groups to establish consensus on stage-gate specific criteria that human risk assessment (HRA) models for manufactured nanomaterials (MN) need to comply with. During the decisive steps in the innovation process, which can be described in a simplified way as stage-gates, it is...
article 2020
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Franken, R. (author), Shandilya, N. (author), Marquart, H. (author), McNally, K. (author), Fransman, W. (author)
Measured data are generally preferred to modelled estimates of exposure. Grouping and read-across is already widely used and accepted approach in toxicology, but an appropriate approach and guidance on how to use existing exposure measurement data on one substance and work situation for another substance and/or work situation is currently not...
article 2020
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Franken, R. (author), Maggos, T. (author), Stamatelopoulou, A. (author), Loh, M. (author), Kuijpers, E. (author), Bartzis, J. (author), Steinle, S. (author), Cherrie, J.W. (author), Pronk, A. (author)
The aim of this study was to (a) develop a method for converting particle number concentrations (PNC) obtained by Dylos to PM2.5 mass concentrations, (b) compare this conversion with similar methods available in the literature, and (c) compare Dylos PM2.5 obtained using all available conversion methods with gravimetric samples. Data were...
article 2019
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Marquart, H. (author), Franken, R. (author), Goede, H. (author), Fransman, W. (author), Schinkel, J. (author)
The ECETOC TRA model (presently version 3.1) is often used to estimate worker inhalation and dermal exposure in regulatory risk assessment. The dermal model in ECETOC TRA has not yet been validated by comparison with independent measured exposure levels. This was the goal of the present study. Measured exposure levels and relevant contextual...
article 2017
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