Prenatal exposure to nonpersistent chemical mixtures and fetal growth: A population-based study

BACKGROUND: Prenatal exposure to mixtures of nonpersistent chemicals is universal. Most studies examining these chemicals in association with fetal growth have been restricted to single exposure models, ignoring their potentially cumulative impact. OBJECTIVE: We aimed to assess the association between prenatal exposure to a mixture of phthalates...

Prenatal Exposure to Nonpersistent Chemical Mixtures and Offspring IQ and Emotional and Behavioral Problems

Prenatal exposure to nonpersistent chemicals such as phthalates, bisphenols, and organophosphate (OP) pesticides is ubiquitous and occurs in mixtures. So far, epidemiological studies investigating neurodevelopmental consequences of these exposures have mainly been restricted to single-pollutant models. Thus, we studied the association between...

Fetal Growth Trajectories among Small for Gestational Age Babies and Child Neurodevelopment

Background: Being born small for gestational age (SGA,

Prenatal exposure to organophosphate pesticides and brain morphology and white matter microstructure in preadolescents

Background: Prenatal exposure to organophosphate (OP) pesticides associate with impaired neurodevelopment in humans and animal models. However, much uncertainty exists about the brain structural alterations underlying these associations. The objective of this study was to determine whether maternal OP pesticide metabolite concentrations in urine...

Phthalate and bisphenol exposure during pregnancy and offspring nonverbal IQ

BACKGROUND: Prenatal exposures to phthalates and bisphenols are associated with impaired brain development in animals. However, epidemiological studies investigating the association between prenatal phthalate or bisphenol exposure and cognition have produced mixed findings and mostly had modest sample sizes and measured the exposure during the...

Organophosphate Pesticide Metabolite Concentrations in Urine during Pregnancy and Offspring offspring attention-deficit hyperactivity disorder and autistic traits

Background: Prenatal exposure to organophosphate (OP) pesticides has been associated with altered neuronal cell development and behavioral changes in animal offspring. However, the few studies investigating the association between prenatal OP pesticide exposure and neurodevelopmental outcomes such as Attention-Deficit Hyperactivity Disorder ...

Organophosphate pesticide exposure in pregnancy in association with ultrasound and delivery measures of fetal growth

Background: Perturbations in fetal growth may have adverse consequences for childhood and later life health. Organophosphate pesticide (OP) exposure has been associated with reduced birth weight at delivery but results are not consistent. We investigated this question by utilizing ultrasound measures of size in utero in combination with measures...