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TNO Kwaliteit van Leven (author), van Ommen, B. (author), Bouwman, J. (author), Dragsted, L.O. (author), Drevon, C.A. (author), Elliott, R. (author), de Groot, P. (author), Kaput, J. (author), Mathers, J.C. (author), Müller, M. (author), Pepping, F. (author), Saito, J. (author), Scalbert, A. (author), Radonjic, M. (author), Rocca-Serra, P. (author), Travis, A. (author), Wopereis, S. (author), Evelo, C.T. (author)The challenge of modern nutrition and health research is to identify food-based strategies promoting life-long optimal health and well-being. This research is complex because it exploits a multitude of bioactive compounds acting on an extensive network of interacting processes. Whereas nutrition research can profit enormously from the revolution...article 2010
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TNO Kwaliteit van Leven (author), van Ommen, B. (author), El-Sohemy, A. (author), Hesketh, J. (author), Kaput, J. (author), Fenech, M. (author), Evelo, C.T. (author), McArdle, H.J. (author), Bouwman, J. (author), Lietz, G. (author), Mathers, J.C. (author), Fairweather-Tait, S. (author), van Kranen, H. (author), Elliott, R. (author), Wopereis, S. (author), Ferguson, L.R. (author), Méplan, C. (author), Perozzi, G. (author), Allen, L. (author), Rivero, D. (author)Micronutrients influence multiple metabolic pathways including oxidative and inflammatory processes. Optimum micronutrient supply is important for the maintenance of homeostasis in metabolism and, ultimately, for maintaining good health. With advances in systems biology and genomics technologies, it is becoming feasible to assess the activity of...article 2010
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TNO Kwaliteit van Leven (author), van Ommen, B. (author), Keijer, J. (author), Kleemann, R. (author), Elliott, R. (author), Drevon, C.A. (author), McArdle, H. (author), Gibney, M. (author), Müller, M. (author)In quantifying the beneficial effect of dietary interventions in healthy subjects, nutrition research meets a number of new challenges. Inter individual variation in biomarker values often is larger than the effect related to the intervention. Healthy subjects have a remarkable capacity to maintain homeostasis, both through direct metabolic...article 2008
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TNO Kwaliteit van Leven (author), Kaput, J. (author), Ordovas, J.M. (author), Ferguson, L. (author), van Ommen, B. (author), Rodriguez, R.L. (author), Allen, L. (author), Ames, B.N. (author), Dawson, K. (author), German, B. (author), Krauss, R. (author), Malyj, W. (author), Archer, M.C. (author), Barnes, S. (author), Bortholomew, A. (author), Birk, R. (author), van Bladeren, P. (author), Bradford, K.J. (author), Brown, K.H. (author), Caetano, R. (author), Castle, D. (author), Chadwick, R. (author), Clarke, S. (author), Clemént, K. (author), Cooney, C.A. (author), Corella, D. (author), da Cruz, I.B.M. (author), Daniel, H. (author), Duster, T. (author), Ebbesson, S.O.E. (author), Elliott, R. (author), Fairweather-Tait, S. (author), Felton, J. (author), Fenech, M. (author), Finley, J.W. (author), Fogg-Johnson, N. (author), Gill-Garrison, R. (author), Gibney, M.J. (author), Gillies, P.J. (author), Gustafsson, J.A. (author), Hartman IV, J.L. (author), He, L. (author), Hwang, J.K. (author), Jais, J.P. (author), Jang, Y. (author), Joost, H. (author), Junien, C. (author), Kanter, M. (author), Kibbe, W.A. (author), Koletzko, B. (author), Korf, B.R. (author), Kornman, K. (author), Krempin, D.W. (author), Langin, D. (author), Lauren, D.R. (author), Lee, J.H. (author), Leveille, G.A. (author), Lin, S.J. (author), Mathers, J. (author), Mayne, M. (author), McNabb, W. (author), Milner, J.A. (author), Morgan, P. (author), Muller, M. (author), Nikolsky, Y. (author), van der Ouderaa, F. (author), Park, T. (author), Pensel, N. (author), Perez-Jimenez, F. (author), Poutanen, K. (author), Roberts, M. (author), Saris, W.H.M. (author), Schuster, G. (author), Shelling, A.N. (author), Simopoulos, A.P. (author), Southon, S. (author), Shyong Tai, E. (author), Towne, B. (author), Trayhurn, P. (author), Uauy, R. (author), Visek, W.J. (author), Warden, C. (author), Weiss, R. (author), Wiencke, J. (author), Winkler, J. (author), Wolff, G.L. (author), Zhao-Wilson, X. (author), Zucker, J.D. (author)Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can...article 2005
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TNO Kwaliteit van Leven TNO Voeding (author), Garosi, P. (author), de Filippo, C. (author), van Erk, M. (author), Rocca-Serra, P. (author), Sansone, S.A. (author), Elliott, R. (author)Microarrays represent a powerful tool for studies of diet-gene interactions. Their use is, however, associated with a number of technical challenges and potential pitfalls. The cost of microarrays continues to drop but is still comparatively high. This, coupled with the complex logistical issues associated with performing nutritional microarray...article 2005
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- Elliott, R. (author), Ong, T.J. (author), TNO Voeding (author) article 2002