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Draisma, H.H.M. (author), Reijmers, T.H. (author), van Kloet, F.D. (author), Bobeldijk-Pastorova, I. (author), Spies-Faber, E. (author), Vogels, J.T.W.E. (author), Meulman, J.J. (author), Boomsma, D.I. (author), van Greef, J.D. (author), Hankemeier, T. (author), TNO Kwaliteit van Leven (author)Combination of data sets from different objects (for example, from two groups of healthy volunteers from the same population) that were measured on a common set of variables (for example, metabolites or peptides) is desirable for statistical analysis in "omics" studies because it increases power. However, this type of combination is not directly...article 2010
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TNO Kwaliteit van Leven (author), Draisma, H.H.M. (author), Reijmers, T.H. (author), Bobeldijk-Pastorova, I. (author), Meulman, J.J. (author), van Estourgie-Burk, G.F. (author), Bartels, M. (author), Ramaker, R. (author), van der Greef, J. (author), Boomsma, D.I. (author), Hankemeier, T. (author)Differences in genetic background and/or environmental exposure among individuals are expected to give rise to differences in measurable characteristics, or phenotypes. Consequently, genetic resemblance and similarities in environment should manifest as similarities in phenotypes. The metabolome reflects many of the system properties, and is...article 2008