Searched for: author:"Dijk, K."
(1 - 13 of 13)
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Otten, W. (author), de Hoogh, I.M. (author), van Keulen, H. (author), Krijger, J.M. (author), van Dijk, K. (author), Berbée, S. (author), van Empelen, P. (author)
Poster Wednesday Session 3 (Policy & Practice, Research and Teaching)’, inclusief poster abstract.
conference paper 2019
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Slagter-Roukema, T. (author), van der Velden, K. (author), Vos, G. (author), Aalhuizen, I. (author), van Melsen, N. (author), Waelput, A. (author), Feitsma, H. (author), Meijer, S. (author), Rijnders, M. (author), Vink, R. (author), van der Meulen, L. (author), Vermolen, J. (author), Koch, L. (author), Kluiters, M. (author), Kirpestein, C. (author), Dijk, K. (author)
De handreiking Kwetsbare Zwangeren van de KNOV in samenwerking met de werkgroep Regionale aanpak kwetsbare zwangere vrouwen, is een zeer praktijkgerichte aanpak. Hierin staat beschreven wat zorgverleners in de eigen regio kunnen doen voor de groep kwetsbare zwangeren. Denk aan het in kaart brengen van het probleem aan de hand van de juiste...
book 2017
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van der Tuin, S.J. (author), Kühnast, S. (author), Berbée, J. (author), Verschuren, L. (author), Pieterman, E.J. (author), Havekes, L.M. (author), van der Hoorn, J.W. (author), Rensen, P.C. (author), Jukema, J.W. (author), Princen, H.M. (author), Willems van Dijk, K. (author), Wang, Y. (author)
Recently, we showed in APOE*3-Leiden.CETP mice that anacetrapib attenuated atherosclerosis development by reducing (V)LDL-C rather than by raising HDL-C. Here, we investigated the mechanism by which anacetrapib reduces (V)LDL-C and whether this effect was dependent on the inhibition of CETP. APOE*3-Leiden.CETP mice were fed a Western type diet...
article 2015
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Heemskerk, M.M. (author), van den Berg, S.A. (author), Pronk, A.C.M. (author), van Klinken, J.B. (author), Boon, M.R. (author), Havekes, L.M. (author), Rensen, P.C.N. (author), Willems van Dijk, K. (author), van Harmelen, V. (author)
The lipid-lowering effect of niacin has been attributed to the inhibition of cAMP production in adipocytes, thereby inhibiting intracellular lipolysis and release of nonesterified fatty acids (NEFA) to the circulation. However, long-term niacin treatment leads to a normalization of plasma NEFA levels and induces insulin resistance, for which the...
article 2014
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Louwe, M.C. (author), Karper, J.C. (author), de Vries, M.R. (author), Nossent, A.Y. (author), Bastiaansen, A.J.N.M. (author), van der Hoorn, J.W.A. (author), Willems Van Dijk, K. (author), Rensen, P.C.N. (author), Steendijk, P. (author), Smit, J.W.A. (author), Quax, P.H.A. (author)
Background Toll-like receptor-4 (TLR4), a receptor of the innate immune system, is suggested to have detrimental effects on cardiac function after myocardial infarction (MI). RP105 (CD180) is a TLR4 homolog lacking the intracellular signaling domain that competitively inhibits TLR4-signaling. Thus, we hypothesized that RP105 deficiency, by...
article 2014
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Louwe, M.C. (author), Karper, J.C. (author), de Vries, M.R. (author), Bastiaansen, A.J.N.M. (author), van der Hoorn, J.W.A. (author), Willems Van Dijk, K. (author), Rensen, P.C.N. (author), Steendijk, P. (author), Smit, J.W.A. (author), Quax, P.H.A. (author)
Purpose: Toll-like receptor-4 (TLR4), a receptor of the innate immune system, is suggested to have detrimental effects on cardiac function after myocardial infarction (MI). RP105 (CD180) is a TLR4 homolog lacking the intracellular signalling domain that competitively inhibits TLR4-signalling. Thus, we hypothesized that RP105 deficiency, by...
article 2014
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Wang, Y. (author), Parlevliet, E.T. (author), Geerling, J.J. (author), van der Tuin, S.J.L. (author), Zhang, H. (author), Bieghs, V. (author), Jawad, A.H.M. (author), Shiri-Sverdlov, R. (author), Bot, I. (author), de Jager, S.C.A. (author), Havekes, L.M. (author), Romijn, J.A. (author), Willems Van Dijk, K. (author), Rensen, P.C.N. (author)
Background and Purpose The aetiology of inflammation in the liver and vessel wall, leading to non-alcoholic steatohepatitis (NASH) and atherosclerosis, respectively, shares common mechanisms including macrophage infiltration. To treat both disorders simultaneously, it is highly important to tackle the inflammatory status. Exendin-4, a glucagon...
article 2014
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Coomans, C.P. (author), van den Berg, S.A. (author), Lucassen, E.A. (author), Houben, T. (author), Pronk, A.C. (author), van der Spek, R.D. (author), Kalsbeek, A. (author), Biermasz, N.R. (author), Willems van Dijk, K. (author), Romijn, J.A. (author), Meijer, J.H. (author)
Disturbances in the circadian system are associated with the development of type 2 diabetes mellitus. Here, we studied the direct contribution of the suprachiasmatic nucleus (SCN), the central pacemaker in the circadian system, in the development of insulin resistance. Exclusive bilateral SCN lesions in male C57Bl/6J mice, as verified by...
article 2013
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van Klinken, J.B. (author), van den Berg, S.A.A. (author), Havekes, L.M. (author), Willems Van Dijk, K. (author)
Physical activity (PA) is a main determinant of total energy expenditure (TEE) and has been suggested to play a key role in body weight regulation. However, thus far it has been challenging to determine what part of the expended energy is due to activity in freely moving subjects. We developed a computational method to estimate activity related...
article 2012
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Gaubius instituut TNO (author), Jong, M.C. (author), Willems-van Dijk, K. (author), Dahlmans, V.E.H. (author), van der Boom, H. (author), Kobayashi, K. (author), Oka, K. (author), Siest, G. (author), Chan, L. (author), Hofker, M.H. (author), Havekes, L.M. (author)
We have shown previously that human apolipoprotein (apo)Cl transgenic mice exhibit hyperlipidaemia, due primarily to an impaired clearance of very-low-density lipoprotein (VLDL) particles from the circulation. In the absence of at least the low-density-lipoprotein receptor (LDLR), it was shown that APOCI overexpression in transgenic mice...
article 1999
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Willems van Dijk, K. (author), Hofker, M.H. (author), Havekes, L.M. (author), Frants, R.R. (author), TNO Preventie en Gezondheid (author)
bookPart 1996
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Willems van Dijk, K. (author), TNO Preventie en Gezondheid (author)
article 1995
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Willems van Dijk, K. (author), Steketee, K. (author), Havekes, L. (author), Frants, R. (author), Hofker, M. (author), TNO Preventie en Gezondheid (author)
A novel 12- and 15-lipoxygenase related gene was isolated from a mouse strain 129 genomic phage library in a screen with a human 15-lipoxygenase cDNA probe. The complete genomic sequence revealed 14 exons and 13 introns covering 7.3 kb of DNA. The splice junctions were verified from the cDNA sequences of a series of overlapping RT-PCR products....
article 1995
Searched for: author:"Dijk, K."
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