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Teunis, M.A.T. (author), Spiekstra, S.W. (author), Smits, M. (author), Adriaens, E. (author), Eltze, T. (author), Galbiati, V. (author), Krul, C.A.M. (author), Landsiedel, R. (author), Pieters, R. (author), Reinders, J. (author), Roggen, E. (author), Corsini, E. (author), Gibbs, S. (author)This study describes the international ring trial of the epidermal-equivalent (EE) sensitizer potency assay. This assay does not distinguish a sensitizer from a non-sensitizer, but may classify known skin sensitizers according to their potency. It assesses the chemical concentration resulting in 50% cytotoxicity (EE-EC50) or the 2-fold increase...article 2014
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Teunis, M. (author), Corsini, E. (author), Smits, M. (author), Madsen, C.B. (author), Eltze, T. (author), Ezendam, J. (author), Galbiati, V. (author), Gremmer, E. (author), Krul, C.A.M. (author), Landin, A. (author), Landsiedel, R. (author), Pieters, R. (author), Rasmussen, T.F. (author), Reinders, J. (author), Roggen, E. (author), Spiekstra, S. (author), Gibbs, S. (author)At present, the identification of potentially sensitizing chemicals is carried out using animal models. However, it is very important from ethical, safety and economic point of view to have biological markers to discriminate allergy and irritation events, and to be able to classify sensitizers according to their potency, without the use of...article 2013
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Hartung, T. (author), Blaauboer, B.J. (author), Bosgra, S. (author), Carney, E. (author), Coenen, J. (author), Conolly, R.B. (author), Corsini, E. (author), Green, S. (author), Faustman, E.M. (author), Gaspari, A. (author), Hayashi, M. (author), Hayes, A.W. (author), Hengstler, J.G. (author), Knudsen, L.E. (author), Knudsen, T.B. (author), McKim, J.M. (author), Pfaller, W. (author), Roggen, E.L. (author)The European cosmetics legislation foresees a review in 2011 and possible postponement of the 2013 marketing ban to enforce the testing ban for systemic and repeated-dose animal tests. For this purpose, a 119-page report commissioned by the European Commission was published recently. Here, a group of 17 independent experts from the US, Europe,...article 2011
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- Kimber, I. (author), Agius, R. (author), Basketter, D.A. (author), Corsini, E. (author), Cullinan, P. (author), Dearman, R.J. (author), Gimenez-Arnau, E. (author), Greenwell, L. (author), Hartung, T. (author), Kuper, F. (author), Maestrelli, P. (author), Roggen, E. (author), Rovida, C. (author), Casati, S. (author), TNO Kwaliteit van Leven (author) article 2007
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- Zuang, V. (author), Balls, M. (author), Botham, P.A. (author), Coquette, A. (author), Corsini, E. (author), Curren, R.D. (author), Elliott, G.R. (author), Fentem, J.H. (author), Heylings, J.R. (author), Liebsch, M. (author), Medina, J. (author), Roguet, R. (author), van de Sandt, J.J.M. (author), Wiemann, C. (author), Worth, A.P. (author), TNO Voeding (author) article 2002
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- van de Sandt, J. (author), Roguet, R. (author), Cohen, C. (author), Esdaile, D. (author), Ponec, M. (author), Corsini, E. (author), Barker, C. (author), Fusenig, N. (author), Liebsch, M. (author), Benford, D. (author), de Brugerolle de Fraissinette, A. (author), Fartasch, M. (author) article 1999
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- van de Sandt, J. (author), Roguet, R. (author), Cohen, C. (author), Esdaile, D. (author), Ponec, M. (author), Corsini, E. (author), Barker, C. (author), Fusenig, N. (author), Liebsch, M. (author), Benford, D. (author), de Franissinette, A. (author), Fartasch, M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author) article 1999