Normal oxidative stress and enhanced lipoprotein resistance to in vitro oxidation in hypertriglyceridemia Effects of bezafibrate therapy

Although there is evidence that hyperlipidemia and predominance of small dense low density lipoproteins (LDLs) are associated with increased oxidative stress, the oxidation status in patients with hypertriglyceridemia (HTG) has not been studied in detail. Therefore, we studied urinary levels of F2-isoprostanes (8-isoprostaglandin F(2α) and 2,3...

No effect of consumption of green and black tea on plasma lipid and antioxidant levels and on LDL Oxidation in smokers

Intake of flavonoids is associated with a reduced cardiovascular risk. Oxidation of LDL is a major step in atherogenesis, and antioxidants may protect LDL from oxidation. Because tea is an important source of flavonoids which are strong antioxidants, we have assessed in a randomized, placebo-controlled study the effect of consumption of black...

Seasonal variation in low density lipoprotein oxidation and antioxidant status

Effect of 17β-estradiol on plasma lipids and LDL oxidation in postmenopausal women with type II diabetes mellitus

In type II diabetes mellitus the altered hormonal state after menopause may represent an additional cardiovascular risk factor. Estrogen replacement therapy (ERT) is associated with a decreased cardiovascular risk, at least in nondiabetic post-menopausal women. We studied the effect of ERT on plasma lipids and lipoproteins and on LDL oxidation...

The effect of medrogestone on plasma lipids and lipoproteins in postmenopausal women using conjugated estrogens: An open randomized comparative study

Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women

There is accumulating evidence that oxidative modification of LDL is an important step in the process of atherogenesis and that antioxidants may protect LDL from oxidation. We and others have previously shown that ingestion of pharmacological doses of the antioxidant D,L-α-tocopherol (vitamin E), far above the recommended daily intake (ie, 12 to...

Liver parenchymal cells differ from the fat-storing cells in their lipid composition

The neutral lipid and phospholipid compositions of purified sinusoidal (fat-storing, endothelial and Kupffer) cells, parenchymal cells and liver homogenates were determined by thin layer chromatography. In addition, the retinoid content of the same purified cell populations was determined by high performance liquid chromatography. From each cell...