Searched for: author%3A%22Brosstad%2C+F.%22
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Sandbæk, G. (author), Bjørnsen, S. (author), Sobel, J.H. (author), Nieuwenhuizen, W. (author), Matsueda, G. (author), Brosstad, F. (author), Gaubius Instituut TNO (author)
The aim of this study was to characterize soluble fibrin(ogen) species in human, arterial, in-vivo-formed thrombi, using the immunoblotting technique. Specimens were collected via intra-arterial catheters in six patients scheduled for catheter-directed thrombolysis. Unreduced and reduced samples of the supernatants from the arterial thrombi...
article 2000
Haddeland, U. (author), Sletten, K. (author), Bennick, A. (author), Nieuwenhuizen, W. (author), Brosstad, F. (author), Gaubius Instituut TNO (author)
The present paper shows that conformationally changed fibrinogen can expose the sites Aα-(148-160) and γ-(312-324) involved in stimulation of the tissue-type plasminogen activator (t-PA)-catalysed plasminogen activation. The exposure of the stimulating sites was determined by ELISA using mABs directed to these sites, and was shown to coincide...
article 1996
Grøn, B. (author), Filion-Myklebust, C. (author), Benninck, A. (author), Nieuwenhuizen, W. (author), Matsueda, G.R. (author), Brosstad, F. (author), Gaubius instituut Instituut voor verouderings- en vaatziekten onderzoek TNO (author)
alpha-polymer formation, as opposed to gamma-chain dimerization has been considered a relatively late event in factor XIII-induced fibrin stabilization. Recently it has been shown, however, that plasma from healthy individuals and from patients with fibrinaemia contains small amounts of soluble fibrin/fibrinogen oligomers interlinked through...
article 1992