Searched for: author:"Boessen, R."
(1 - 9 of 9)
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Krone, T. (author), Boessen, R. (author), Bijlsma, S. (author), van Stokkum, R. (author), Clabbers, N.D.S. (author), Pasman, W.J. (author)
Background. N-of-1 designs gain popularity in nutritional research because of the improving technological possibilities, practical applicability and promise of increased accuracy and sensitivity, especially in the field of personalized nutrition. This move asks for a search of applicable statistical methods. Objective. To demonstrate the...
article 2020
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Wopereis, S. (author), Stroeve, J.H.M. (author), Stafleu, A. (author), Bakker, G.C.M. (author), Burggraaf, J. (author), van Erk, M.J. (author), Pellis, L. (author), Boessen, R. (author), Kardinaal, A.A.F. (author), van Ommen, B. (author)
Background: A key feature of metabolic health is the ability to adapt upon dietary perturbations. Recently, it was shown that metabolic challenge tests in combination with the new generation biomarkers allow the simultaneous quantification of major metabolic health processes. Currently, applied challenge tests are largely non-standardized. A...
article 2017
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Bekker, C. (author), Fransman, W. (author), Boessen, R. (author), Oerlemans, A. (author), Ottenbros, I.B. (author), Vermeulen, R. (author)
Background: Nano-specific inhalation exposure models could potentially be effective tools to assess and control worker exposure to nano-objects, and their aggregates and agglomerates (NOAA). However, due to the lack of reliable and consistent collected NOAA exposure data, the scientific basis for validation of the existing NOAA exposure models...
article 2017
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Berk, K.A. (author), Mulder, M.T. (author), Verhoeven, A.J.M. (author), van Wietmarschen, H. (author), Boessen, R. (author), Pellis, L.P. (author), van Spijker, A.T. (author), Timman, R. (author), Ozcan, B. (author), Sijbrands, E.J.G. (author)
Aims A very low calorie diet improves the metabolic regulation of obesity related type 2 diabetes, but not for all patients, which leads to frustration in patients and professionals alike. The aim of this study was to develop a prediction model of diet-induced weight loss in type 2 diabetes. Methods 192 patients with type 2 diabetes and BMI>27...
article 2016
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Brouwer, D. (author), Boessen, R. (author), van Duuren-Stuurman, B. (author), Bard, D. (author), Moehlmann, C. (author), Bekker, C. (author), Fransman, W. (author), Entink, R.K. (author)
Tiered or stepwise approaches to assess occupational exposure to nano-objects, and their agglomerates and aggregates have been proposed, which require decision rules (DRs) to move to a next tier, or terminate the assessment. In a desk study the performance of a number of DRs based on the evaluation of results from direct reading instruments was...
article 2016
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Tan, E. (author), Boessen, R. (author), Fishwick, D. (author), Klein Entink, R. (author), Meijster, T. (author), Pronk, A. (author), van Duuren-Stuurman, B. (author), Warren, N. (author)
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease that is thought to affect over one million people in Great Britain. The main factor contributing to the development of COPD is tobacco smoke. This paper presents a microsimulation model for the development of COPD, incorporating population dynamics and trends in smoking. The...
article 2015
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van Deurssen, E. (author), Meijster, T. (author), Oude Hengel, K.M. (author), Boessen, R. (author), Spaan, S. (author), Tielemans, E. (author), Heederik, D. (author), Pronk, A. (author)
There is little evidence with respect to the effectiveness of intervention programs that focus on the reduction of occupational quartz exposure in the construction industry. This article evaluates the effectiveness of a multidimensional intervention which was aimed at reducing occupational quartz exposure among construction workers by increasing...
article 2015
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Boessen, R. (author), Lambers Heerspink, H.J. (author), de Zeeuw, D. (author), Grobbee, D.E. (author), Groenwold, R.H.H. (author), Roes, K.C.B. (author)
Background: In many therapeutic areas, individual patient markers have been identified that are associated with differential treatment response. These markers include both baseline characteristics, as well as short-term changes following treatment. Using such predictive markers to select subjects for inclusion in randomized clinical trials could...
article 2014
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Pronk, A. (author), Boessen, R. (author), Deurssen, E. (author), Meijster, T. (author), Klein Entink, R. (author), van Duuren-Stuurman, B. (author), Heederik, D. (author), Warren, N. (author), Tan, E. (author)
A multidimensional intervention study was performed to reduce personal quartz exposure in the Dutch construction industry (poster #0399). The intervention study focused on increasing the use of technical control measures (properly) among three high risk occupations by targeting organizational and behavioral factors The objective of this study...
public lecture 2014
Searched for: author:"Boessen, R."
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