Searched for: author%3A%22Blankvoort%2C+B.M.G.%22
(1 - 5 of 5)
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Vermeulen, M. (author), Boerboom, A.M.M.J.F. (author), Blankvoort, B.M.G. (author), Aarts, J.M.M.J.G. (author), Rietjens, I.M.C.M. (author), van Bladeren, P.J. (author), Vaes, W.H.J. (author), TNO Kwaliteit van Leven (author)
Isothiocyanates are electrophiles that are able to induce phase II biotransformation enzyme gene expression via an electrophile-responsive element (EpRE) in the gene regulatory region. To study the potency of different isothiocyanates to induce the expression of EpRE-regulated genes, a Hepa-1c1c7 luciferase reporter cell line was exposed to...
article 2009
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Blankvoort, B.M.G. (author), Rodenburg, R.J.T. (author), Murk, A.J. (author), Koeman, J.H. (author), Schilt, R. (author), Aarts, J.M.M.J.G. (author), TNO Kwaliteit van Leven (author)
This paper describes the screening of 22 extracts from 18 different aquatic environmental samples for androgenic activity, including indirect and interactive effects on androgen receptor (AR)-mediated signal transduction, using the AR-LUX bioassay. Four samples, originating from an industrial wastewater treatment plant (WTP) or the river Meuse,...
article 2005
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Blankvoort, B.M.G. (author), Aarts, J.M.M.J.G. (author), Schilt, R. (author), Geerdink, P. (author), Spenkelink, B. (author), Rodenburg, R.J.T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Despite a ban by the European Union, the use of anabolic steroids and repartitioning agents in cattle is still occasionally observed. Due to continuing improvements in analytical techniques, very low detection limits for individual compounds have been achieved. In response to these developments, cocktails composed of several steroids have been...
article 2003
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Blankvoort, B.M.G. (author)
doctoral thesis 2003
document
Blankvoort, B.M.G. (author), de Groene, E.M. (author), van Meeteren-Kreikamp, A.P. (author), Witkamp, R.F. (author), Rodenburg, R.J.T. (author), Aarts, J.M.M.J.G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The aim of the work described in this report is to develop and characterize a cell-based androgen reporter assay. For this purpose, the androgen receptor (AR) expressing human breast cancer cell line T47D was stably transfected with a luciferase gene under transcriptional control of the PB-ARE-2 androgen response element. The application of this...
article 2001
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