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van der Heijden, R.A. (author), Bijzet, J. (author), Meijers, W.C. (author), Yakala, G.K. (author), Kleemann, R. (author), Nguyen, T.Q. (author), de Boer, R.A. (author), Schalkwijk, C.G. (author), Hazenberg, B.P.C. (author), Tietge, U.J.F. (author), Heeringa, P. (author)Obesity-induced inflammation presumably accelerates the development of chronic kidney diseases. However, little is known about the sequence of these inflammatory events and their contribution to renal pathology. We investigated the effects of obesity on the evolution of age-dependent renal complications in mice in conjunction with the...article 2015
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Abdulahad, D.A. (author), Westra, J. (author), Reefman, E. (author), Zuidersma, E. (author), Bijzet, J. (author), Limburg, P.C. (author), Kallenberg, C.G.M. (author), Bijl, M. (author)Photosensitivity is characteristic of systemic lupus erythematosus (SLE). Upon ultraviolet B (UVB) exposure, patients develop inflammatory skin lesions in the vicinity of sunburn cells (SBCs). High mobility group box 1 (HMGB1) is released from apoptotic and activated cells and exerts inflammatory actions through ligation to its receptors....article 2013