Searched for: author%3A%22Beems%2C+R.B.%22
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Lina, B.A.R. (author), Woutersen, R.A. (author), Bruijntjes, J.P. (author), van Benthem, J. (author), van den Berg, J.A.H. (author), Monbaliu, J. (author), Thoolen, B.J.J.M. (author), Beems, R.B. (author), van Kreijl, C.F. (author), TNO Voeding (author)
As part of the international evaluation program coordinated by ILSI/HESI, the potential of DNA repair deficient Xpa-/- mice and the double knockout Xpa-/-.p53+/- mice for short term carcinogenicity assays was evaluated. For comparison also wild-type C57BL/6 mice (WT) were included in these studies. Four test compounds were administered to groups...
article 2004
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Gezondheidsorganisatie TNO Nederlands Instituut voor Praeventieve Geneeskunde TNO (author), Stouten, J.T.J. (author), Feron, V.J. (author), Beems, R.B. (author), Boleij, J.S.M. (author), Brokamp, J.J.A.M. (author), Heederik, D.J.J. (author), Henderson, P.T. (author), de Jong, G. (author), de Mik, G. (author), Molier-Bloot, J. (author), Noordam, P.C. (author), Roelfzema, H. (author), Smid, T. (author), Swaen, G.M.H. (author), Verschuuren, H.G. (author), Wibowo, A.A.E. (author), de Wit, F. (author), Bouwman, C.A. (author), van der Burght, A.S.A.M. (author)
book 1997
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Feron, V.J. (author), Beems, R.B. (author), Reuzel, P.G.J. (author), Zwart, A. (author), TNO Voeding (author)
bookPart 1996
document
Woutersen, R.A. (author), Beems, R.B. (author), van Garderen-Hoetmer, A. (author), Feron, V.J. (author), TNO Voeding (author)
bookPart 1996
document
Feron, V.J. (author), Beems, R.B. (author), Reuzel, P.G.J. (author), Zwart, A. (author), TNO Voeding (author)
bookPart 1996
document
Centraal Instituut voor Voedingsonderzoek TNO (author), Feron, V.J. (author), Beems, R.B. (author), Boleij, J.S.M. (author), Brokamp, J.J.A.M. (author), Henderson, P.T. (author), de Jong, G. (author), de Mik, G. (author), Molier-Bloot, J. (author), Noordam, P.C. (author), Roelfzema, H. (author), Smid, T. (author), Swaen, G.M.H. (author), Verschuuren, H.G. (author), Wibowo, A.A.E. (author), de Wit, F. (author), Hoeksema, C. (author)
report 1995
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Bogdanffy, M.S. (author), Dreef-van der Meulen, H.C. (author), Beems, R.B. (author), Feron, V.J. (author), Cascieri, T.C. (author), Tyler, T.R. (author), Vinegar, M.B. (author), Rickard, R.W. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
article 1994
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Stouten, J.T.J. (author), Feron, V.J. (author), Beems, R.B. (author), Boleij, J.S.M. (author), Brokamp, J.J.A.M. (author), Henderson, P.T. (author), de Jong, G. (author), de Mik, G. (author), Molier-Bloot, J. (author), Noordam, P.C. (author), Roelfzema, H. (author), Smid, T. (author), Swaen, G.M.H. (author), Verschuuren, H.G. (author), Wibowo, A.A.E. (author), de Wit, F. (author), Hoeksema, C. (author)
report 1994
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Beems, R.B. (author), Feron, V.J. (author), Centraal Instituut voor Voedingsonderzoek TNO Instituut voor Toxicologie en Voeding TNO (author)
bookPart 1992
document
Kuper, C.F. (author), Beems, R.B. (author), Bruijntjes, J.P. (author), Schuurman, H.J. (author), Vos, J.G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
bookPart 1992
document
Rutten, A.A.J.J.L. (author), Wilmer, J.W.G.M. (author), Beems, R.B. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The effects of cigarette smoke condensate (CSC) and all-trans retinol on the cell proliferative activity of vitamin A-deprived hamster tracheal epithelium have been studied in vitamin A-deficient, serum-free, hormone-supplemented medium in organ culture. In the absence of retinol, CSC induced a dose-dependent increase in labelig index (LI)...
article 1988
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Rutten, A.A.J.J.L. (author), Beems, R.B. (author), Wilmer, J.W.G.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The effects of all-trans retinol and cigarette smoke condensate (CSC) on tissue morphology and cellular differentiation were investigated in vitamin A-deprived tracheal epithelium cultured in vitamin A- and serum-free hormone-supplemented medium. Physiological retinol concentrations prevented the development of hyperplasia and squamous...
article 1988
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Feron, V.J. (author), Beems, R.B. (author)
article 1987
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Beems, R.B. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
article 1986
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Instituut CIVO-Toxicologie en voeding TNO (author), Kroes, R. (author), Beems, R.B. (author), Bosland, M.C. (author), Bunnik, G.S.J. (author), Sinkeldam, E.J. (author)
Dietary factors are now considered to be among the most important environmental risk determinations for cancer. In addition to epidemiological studies, experimental animal studies are an important tool to investigate dietary modulation in carcinogenesis. Results of recent experimental studies on the effect of some nutrients indicate that vitamin...
conference paper 1986
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Reynders, J.B.J. (author), Immel, H.R. (author), Scherrenberg, P.M. (author), Feron, V.J. (author), Beems, R.B. (author), Instituut CIVO-Toxicologie en voeding TNO (author)
Two groups of male and female Syrian golden hamsters, of which the trachea was severely injured by electrocoagulation, received 6 weekly intratracheal instillations of benzo[a]pyrene (BaP) + ferric oxide in saline or saline alone. Two comparable groups of hamsters were similarly treated but had an undamaged trachea. The experiment was terminated...
article 1985
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Beems, R.B. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
Chemicals/CAS: benzo[a]pyrene, 50-32-8; retinol, 68-26-8, 82445-97-4; Benzo(a)pyrene, 50-32-8; Benzopyrenes; Vitamin A, 11103-57-4
article 1984
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Centraal Instituut voor Voedingsonderzoek TNO (author), Beems, R.B. (author), van Beek, L. (author)
Chemicals/CAS: benzo[a]pyrene, 50-32-8; Benzo(a)pyrene, 50-32-8; Benzopyrenes; Carcinogens; Dietary Fats; Fatty Acids, Unsaturated.
article 1984
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Reuzel, P.G.J. (author), Feron, V.J. (author), Spit, B.J. (author), Beems, R.B. (author), Kroes, R. (author), Instituut CIVO-Toxicologie en voeding TNO (author)
Cofactors involved in respiratory tract carcinogenesis were studied in Syrian golden hamster or in rats using benzo(a)pyrene as the carcinogenic agent. These factors included severe tissue tissue damage induced by electro-coagulation, glass fibers administered by intratracheal instillation, acetaldehyde as irritant vapor, food restriction, and...
article 1983
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Beems, R.B. (author), Spit, B.J. (author), Koeter, H.B.W.M. (author), Feron, V.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
A variety of gastric lesions can be induced in rats by sodium metabisulfite, including the formation of scattered hyperplastic glands in the fundic mucosa which are exclusively lined by large uniform cells, laden with acidophilic granules. Light and electron microscopy, as enzyme histochemistry, showed that the cells lining these glands are...
article 1982
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