EFFORT-D: results of a randomised controlled trial testing the EFFect of running therapy on depression

Results of a randomised controlled trial testing the EFFect Of Running Therapy on Depression. Background. This randomised controlled trial explored the anti-depressive and health effects of add-on exercise (running therapy or Nordic walking) in patients with Major Depressive Disorder (MDD). Methods. Patients were recruited at three specialised...

EFFORT-D study process evaluation: Challenges in conducting a trial into the effects of running therapy in patients with major depressive disorder

Background: Exercise is currently seen as an effective treatment for major depressive disorder (MDD). However, existing studies have focused mainly on mild-to-moderate depression. The moderate positive effect of exercise found in meta-analyses concerning these studies differs, however, from the harsh daily clinical practice, when trying to...