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van Veenstra, A.F.E. (author), van den Broek, T.A. (author), van der Plas, A.P. (author)
article 2012
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Tott, J.E.E. (author), Pardo, L.M. (author), Fieten, K.B. (author), Vos, M.C. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), Pasmans, S.G.M.A. (author)
Background: Alterations of the skin microbiome have been associated with atopic dermatitis (AD) and its severity. The nasal microbiome in relation to AD severity is less well studied. Objectives: We aimed to characterize the nasal and skin microbiomes in children with AD in relation to disease severity. In addition, we explored the differences...
article 2019
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van Boxtel, E.L. (author), van den Broek, L.A.M. (author), Koppelman, S.J. (author), Vincken, J.-P. (author), Gruppen, H. (author), TNO Kwaliteit van Leven (author)
Mildly extracted peanut allergen Ara h 1 was previously reported to occur as an oligomeric complex. In this paper we describe how the protein in this oligomeric complex interacts noncovalently with phenolic compounds of the proanthocyanidin type. These interactions are being disrupted during anion exchange chromatography, resulting in the...
article 2007
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Tjerkstra, R.W. (author), Woldering, L.A. (author), van den Broek, J.M. (author), Roozeboom, F. (author), Setija, I.D. (author), Vos, W.L. (author)
article 2012
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Wesselink, M. (author), Liu, W. (author), Koornneef, J. (author), van den Broek, M. (author)
High temperature aquifer thermal energy storage (HT-ATES) can contribute to the integration of renewable energy sources in the energy system, the replacement of fossil fuel-based heat supply and the utilization of surplus heat from industrial sources. However, there is limited understanding on the drivers, barriers and conditions of HT-ATES...
article 2018
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Beerends, J.G. (author), van Nieuwenhuizen, K. (author), van den Broek, E.L. (author)
We present PREQUEL: Perceptual Reproduction Quality Evaluation for Loudspeakers. Instead of quantifying the loudspeaker system itself, PREQUEL quantifies the overall loudspeakers' perceived sound quality by assessing their acoustic output using a set of music signals. This approach introduces a major problem: subjects cannot be provided with an...
article 2016
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Milisavljević, N. (author), Bloch, I. (author), van den Broek, S.P. (author), Acheroy, M. (author), TNO Fysisch en Elektronisch Laboratorium (author)
A methodfor modeling andcombination of measures extractedfrom a ground-penetrating radar (GPR) in terms of belief functions within the Dempster-Shafer framework is presentedandillustratedon a real GPR data set. A starting point in the analysis is a preprocessed C-scan of a sand-lane containing some mines andfalse alarms. In order to improve the...
article 2003
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van der Sluis, F. (author), van den Broek, E.L. (author), van Drunen, A. (author), Beerends, J.G. (author)
Bandwidth is still a limiting factor for the Quality of Service (QoS) of mobile communication applications. In particular, for Voice over IP the QoS is not yet as good as for common, well-engineered, public-switched telephone networks. Multisensory communication has been identified as a possibility to moderate this limitation. One of the...
article 2018
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van den Broek, P.J. (author), Haerkens, H.M.J. (author), van Weert, N.J.H.W. (author), Vermeij, P. (author), TNO Preventie en Gezondheid (author)
Objective. To determine whether intravenous home treatment with antimicrobial drugs of patients with an infection is feasible. Design. Descriptive. Setting. Academic Hospital, Leiden, the Netherlands. Method. In October 1992 a programme for intravenous home treatment of patients with infectious diseases was started. The programme was based on...
article 1997
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van Boxtel, E.L. (author), Koppelman, S.J. (author), van den Broek, L.A.M. (author), Gruppen, H. (author), TNO Kwaliteit van Leven (author)
Ber e 1, a major allergen from Brazil nuts, is very stable to in vitro peptic digestion. As heat-induced denaturation may affect protein digestibility, the denaturation behaviour of Ber e 1 was investigated. The denaturation temperature of Ber e 1 varies from approximately 80-110 °C, depending on the pH. Upon heating above its denaturation...
article 2008
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Sadowska, A. (author), van den Broek, T.H.A. (author), Huijberts, H. (author), van de Wouw, N. (author), Kostić, D. (author), Nijmeijer, H. (author)
In this article, the formation control problem for unicycle mobile robots is studied. A distributed virtual structure control strategy with mutual coupling between the robots is proposed. The rationale behind the introduction of the coupling terms is the fact that these introduce additional robustness of the formation with respect to...
article 2011
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van Ree, J.H. (author), Hofker, M.H. (author), van den Broek, J.A.A. (author), van Deursen, J.M.A. (author), van der Boom, H. (author), Frants, R.R. (author), Wieringa, B. (author), Havekes, L.M. (author), Gaubius Instituut TNO (author)
The function of apolipoprotein (apo) C1 in vivo is not well understood. From in vitro studies it has been reported that an excess of apoC1 relative to apoE inhibits receptor-mediated uptake of remnant lipoproteins. In order to gain a better understanding of the role of apoC1 in lipoprotein metabolism in vivo, we have generated apoC1-deficient...
article 1995
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van den Broek, J. (author), van den Berg, C.H. (author)
Al direct vanaf de start van de Nationale Politie is gewerkt aan het opzetten van tien real-time intelligence centra in Nederland. Van daaruit worden 24 uur per dag en zeven dagen in de week agenten op straat actief ondersteund met real-time informatie bij de melding waar ze op af gaan. In de visie van TNO is de kracht van real-time intelligence...
article 2013
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Groot, C.K. (author), van den Broek, W.B.P. (author), Loewenberg, J. (author), Koeman-Stein, N.E. (author), Heidekamp, M. (author), de Schepper, W. (author)
For chemical industries, fresh water availability is a pre-requisite for sustainable operation. However, in many delta areas around the world, fresh water is scarce. Therefore, the E4Water project (http://www.e4water.eu) comprises a case study at the Dow site in Terneuzen, The Netherlands, which is designed to develop commercial applications for...
article 2015
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van Mierlo, M.M.F. (author), Totté, J.E.E. (author), Fieten, K.B. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), Pardo, L.M. (author), Pasmans, S.G.M.A. (author)
Background: The skin microbiome, characterized by an overgrowth of Staphylococcus aureus, plays an important role in the pathogenesis of atopic dermatitis (AD). Multidisciplinary treatment in alpine climate is known for its positive effect on disease severity in children with AD and can result in a different immune response compared with...
article 2019
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van Boxtel, E.L. (author), van den Broek, L.A.M. (author), Koppelman, S.J. (author), Gruppen, H. (author), TNO Kwaliteit van Leven (author)
Legumin proteins Ara h 3 from peanuts and glycinin from soybeans are increasingly described as important allergens. The stability of an allergen's IgE binding capacity towards heating and digestion is considered an important characteristic for food allergens. We investigated the effects of heating and digestion on the IgE binding of Ara h 3 and...
article 2008
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Fiamoncini, J. (author), Yiorkas, A.M. (author), Gedrich, K. (author), Rundle, M. (author), Alsters, S.I. (author), Roeselers, G. (author), van den Broek, T.J. (author), Clavel, T. (author), Lagkouvardos, I. (author), Wopereis, S. (author), Frost, G. (author), van Ommen, B. (author), Blakemore, A.I. (author), Daniel, H. (author)
Bile acids (BA) are signaling molecules with a wide range of biological effects, also identified among the most responsive plasma metabolites in the postprandial state. We here describe this response to different dietary challenges and report on key determinants linked to its interindividual variability. Healthy men and women (n = 72, 62 ± 8 yr,...
article 2017
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van Ommen, B. (author), van den Broek, T. (author), de Hoogh, I. (author), van Erk, M. (author), van Someren, E. (author), Rouhani-Rankouhi, T. (author), Anthony, J.C. (author), Hogenelst, K. (author), Pasman, W. (author), Boorsma, A. (author), Wopereis, S. (author)
Personalized nutrition is fast becoming a reality due to a number of technological, scientific, and societal developments that complement and extend current public health nutrition recommendations. Personalized nutrition tailors dietary recommendations to specific biological requirements on the basis of a person’s health status and goals. The...
article 2017
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Burghouts, G.J. (author), Schutte, K (author), ten Hove, R.J.M. (author), van den Broek, S.P. (author), Baan, J. (author), Rajadell, O. (author), van Huis, J.R. (author), van Rest, J.H.C. (author), Hanckmann, P. (author), Bouma, H. (author), Sanroma, G. (author), Evans, M. (author), Ferryman, J. (author)
Threat detection is a challenging problem, because threats appear in many variations and differences to normal behaviour can be very subtle. In this paper, we consider threats on a parking lot, where theft of a truck’s cargo occurs. The theft takes place in very different forms, in the midst of many people who pose no threat. The threats range...
article 2014
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Munsters, C.C.B.M. (author), Kingma, B.R.M. (author), van den Broek, J. (author), Sloet van Oldruitenborgh-Oosterbaan, M.M. (author)
In human sport science, the acute:chronic workload (ACWR) ratio is used to monitor an athlete's preparedness for competition and to assess injury risks. The aim of this study was to investigate whether acute and chronic workload calculations for external and internal loads (e.g. high-speed work distance and associated exertional effort) were...
article 2020
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