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van Veenstra, A.F.E. (author), van den Broek, T.A. (author), van der Plas, A.P. (author)
article 2012
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Keijser, B.J.F. (author), Agamennone, V. (author), van den Broek, T.J. (author), Caspers, M. (author), van de Braak, A. (author), Bomers, R. (author), Havekes, M. (author), Schoen, E. (author), van Baak, M. (author), Mioch, D. (author), Bomers, L. (author), Montijn, R.C. (author)
Background: Antibiotic therapy is commonly used in animal agriculture. Antibiotics excreted by the animals can contaminate farming environments, resulting in long term exposure of animals to sub-inhibitory levels of antibiotics. Little is known on the effect of this exposure on antibiotic resistance. In this study, we aimed to investigate the...
article 2019
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Notenboom, S. (author), Weigand, K.M. (author), Proost, J.H. (author), van Lipzig, M.M. (author), van de Steeg, E. (author), van den Broek, P.H.H. (author), Greupink, R. (author), Russel, F.G.M. (author), Groothuis, G.M.M. (author)
The authors regret the molar unit is incorrectly displayed on the x-axis in Fig. 4A and 4C and on the y-axis in Fig. 4B, 4D and Fig. 5. The correct versions of the figures are displayed below together with the unchanged legends. The authors would like to apologise for any inconvenience caused. DOI of original article: 10.1016/j.ejps.2018.01.007 ...
article 2018
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Tott, J.E.E. (author), Pardo, L.M. (author), Fieten, K.B. (author), Vos, M.C. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), Pasmans, S.G.M.A. (author)
Background: Alterations of the skin microbiome have been associated with atopic dermatitis (AD) and its severity. The nasal microbiome in relation to AD severity is less well studied. Objectives: We aimed to characterize the nasal and skin microbiomes in children with AD in relation to disease severity. In addition, we explored the differences...
article 2019
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van Boxtel, E.L. (author), van den Broek, L.A.M. (author), Koppelman, S.J. (author), Vincken, J.-P. (author), Gruppen, H. (author), TNO Kwaliteit van Leven (author)
Mildly extracted peanut allergen Ara h 1 was previously reported to occur as an oligomeric complex. In this paper we describe how the protein in this oligomeric complex interacts noncovalently with phenolic compounds of the proanthocyanidin type. These interactions are being disrupted during anion exchange chromatography, resulting in the...
article 2007
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Tjerkstra, R.W. (author), Woldering, L.A. (author), van den Broek, J.M. (author), Roozeboom, F. (author), Setija, I.D. (author), Vos, W.L. (author)
article 2012
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van Koppen, A. (author), Verschuren, L. (author), van den Hoek, A.M. (author), Verheij, J. (author), Morrison, M.C. (author), Li, K. (author), Nagabukuro, H. (author), Costessi, A. (author), Caspers, M.P.M. (author), van den Broek, T.J. (author), Sagartz, J. (author), Kluft, C. (author), Beysen, C. (author), Emson, C. (author), van Gool, A.J. (author), Goldschmeding, R. (author), Stoop, R. (author), Bobeldijk-Pastorova, I. (author), Turner, S.M. (author), Hanauer, G. (author), Hanemaaijer, R. (author)
Background & Aims: The incidence of nonalcoholic steatohepatitis (NASH) is increasing. The pathophysiological mechanisms of NASH and the sequence of events leading to hepatic fibrosis are incompletely understood. The aim of this study was to gain insight into the dynamics of key molecular processes involved in NASH and to rank early markers for...
article 2017
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Wesselink, M. (author), Liu, W. (author), Koornneef, J. (author), van den Broek, M. (author)
High temperature aquifer thermal energy storage (HT-ATES) can contribute to the integration of renewable energy sources in the energy system, the replacement of fossil fuel-based heat supply and the utilization of surplus heat from industrial sources. However, there is limited understanding on the drivers, barriers and conditions of HT-ATES...
article 2018
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Beerends, J.G. (author), van Nieuwenhuizen, K. (author), van den Broek, E.L. (author)
We present PREQUEL: Perceptual Reproduction Quality Evaluation for Loudspeakers. Instead of quantifying the loudspeaker system itself, PREQUEL quantifies the overall loudspeakers' perceived sound quality by assessing their acoustic output using a set of music signals. This approach introduces a major problem: subjects cannot be provided with an...
article 2016
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Milisavljević, N. (author), Bloch, I. (author), van den Broek, S.P. (author), Acheroy, M. (author), TNO Fysisch en Elektronisch Laboratorium (author)
A methodfor modeling andcombination of measures extractedfrom a ground-penetrating radar (GPR) in terms of belief functions within the Dempster-Shafer framework is presentedandillustratedon a real GPR data set. A starting point in the analysis is a preprocessed C-scan of a sand-lane containing some mines andfalse alarms. In order to improve the...
article 2003
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van der Sluis, F. (author), van den Broek, E.L. (author), van Drunen, A. (author), Beerends, J.G. (author)
Bandwidth is still a limiting factor for the Quality of Service (QoS) of mobile communication applications. In particular, for Voice over IP the QoS is not yet as good as for common, well-engineered, public-switched telephone networks. Multisensory communication has been identified as a possibility to moderate this limitation. One of the...
article 2018
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van den Broek, P.J. (author), Haerkens, H.M.J. (author), van Weert, N.J.H.W. (author), Vermeij, P. (author), TNO Preventie en Gezondheid (author)
Objective. To determine whether intravenous home treatment with antimicrobial drugs of patients with an infection is feasible. Design. Descriptive. Setting. Academic Hospital, Leiden, the Netherlands. Method. In October 1992 a programme for intravenous home treatment of patients with infectious diseases was started. The programme was based on...
article 1997
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van Boxtel, E.L. (author), Koppelman, S.J. (author), van den Broek, L.A.M. (author), Gruppen, H. (author), TNO Kwaliteit van Leven (author)
Ber e 1, a major allergen from Brazil nuts, is very stable to in vitro peptic digestion. As heat-induced denaturation may affect protein digestibility, the denaturation behaviour of Ber e 1 was investigated. The denaturation temperature of Ber e 1 varies from approximately 80-110 °C, depending on the pH. Upon heating above its denaturation...
article 2008
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Wacoo, A.P. (author), Atukunda, P. (author), Muhoozi, G. (author), Braster, M. (author), Wagner, M. (author), van den Broek, T.J. (author), Sybesma, W. (author), Westerberg, A.C. (author), Iversen, P.O. (author), Kort, R. (author)
article 2020
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Sadowska, A. (author), van den Broek, T.H.A. (author), Huijberts, H. (author), van de Wouw, N. (author), Kostić, D. (author), Nijmeijer, H. (author)
In this article, the formation control problem for unicycle mobile robots is studied. A distributed virtual structure control strategy with mutual coupling between the robots is proposed. The rationale behind the introduction of the coupling terms is the fact that these introduce additional robustness of the formation with respect to...
article 2011
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van Ree, J.H. (author), Hofker, M.H. (author), van den Broek, J.A.A. (author), van Deursen, J.M.A. (author), van der Boom, H. (author), Frants, R.R. (author), Wieringa, B. (author), Havekes, L.M. (author), Gaubius Instituut TNO (author)
The function of apolipoprotein (apo) C1 in vivo is not well understood. From in vitro studies it has been reported that an excess of apoC1 relative to apoE inhibits receptor-mediated uptake of remnant lipoproteins. In order to gain a better understanding of the role of apoC1 in lipoprotein metabolism in vivo, we have generated apoC1-deficient...
article 1995
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Fehlbaum, S. (author), Prudence, K. (author), Kieboom, J. (author), Heerikhuisen, M. (author), van den Broek, T. (author), Schuren, F.H.J. (author), Steinert, R.E. (author), Raederstorff, D. (author)
Recently, the concept of prebiotics has been revisited to expand beyond non-digestible oligosaccharides, and the requirements for selective stimulation were extended to include microbial groups other than, and additional to, bifidobacteria and lactobacilli. Here, the gut microbiota-modulating effects of well-known and novel prebiotics were...
article 2018
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van den Broek, J. (author), van den Berg, C.H. (author)
Al direct vanaf de start van de Nationale Politie is gewerkt aan het opzetten van tien real-time intelligence centra in Nederland. Van daaruit worden 24 uur per dag en zeven dagen in de week agenten op straat actief ondersteund met real-time informatie bij de melding waar ze op af gaan. In de visie van TNO is de kracht van real-time intelligence...
article 2013
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Groot, C.K. (author), van den Broek, W.B.P. (author), Loewenberg, J. (author), Koeman-Stein, N.E. (author), Heidekamp, M. (author), de Schepper, W. (author)
For chemical industries, fresh water availability is a pre-requisite for sustainable operation. However, in many delta areas around the world, fresh water is scarce. Therefore, the E4Water project (http://www.e4water.eu) comprises a case study at the Dow site in Terneuzen, The Netherlands, which is designed to develop commercial applications for...
article 2015
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van den Broek, P.J. (author), Wille, J.C. (author), van Benthem, B.H.B. (author), Perenboom, R.J.M. (author), van den Akker-van Marle, M.E. (author), Nielen, A.M.A. (author)
Indwelling urinary catheters are the main cause of healthcare-associated urinary tract infections. It can be expected that reduction of the use of urinary catheters will lead to decreased numbers of urinary tract infection. The efficacy of an intervention programme to improve adherence to recommendations to reduce the use of urethral catheters...
article 2011
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