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Huisman, L.G.M. (author), Meijer, P. (author), van Griensven, J. (author), Kluft, C. (author), Gaubius Laboratory Instituut voor verouderings- en vaatziekten onderzoek TNO (author)
t-PA depleted citrated plasma was used to prepare standards of different molecular forms of plasminogen activator inhibitor 1 (PAI-1). These standards were used to evaluate the specificity of two new PAI-1 antigen assays: the TintElize PAI-1 antigen assay (cat. no. 210221) and the Innotest PAI-1. Differences in specificity were apparent: the...
article 1992
document
Mpofu, A. (author), Linnemann, A.R. (author), Sybesma, W. (author), Kort, R. (author), Nout, M.J.R. (author), Smid, E.J. (author)
A probiotic dairy product was developed on the basis of a traditional dish called mutandabota to enable resource-poor populations in southern Africa to benefit from a functional food. Mutandabota is widely consumed in rural southern Africa, making it an ideal food matrix to carry probiotics. First, a process to produce probiotic mutandabota was...
article 2014
document
Tavasszy, L.A. (author), TNO Bouw en Ondergrond (author)
article 2010
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Keulen, L. (author), van der Ham, L.V. (author), Kuipers, N.J.M. (author), Hanemaaijer, J.H. (author), Vlugt, T.J.H. (author), Kjelstrup, S. (author)
Membrane distillation is an attractive technology for production of fresh water from seawater. The MemPower® concept, studied in this work, uses available heat (86 °C) to produce pressurized water (2.2 bar and 46 °C) by membrane distillation, which again can be used to power a turbine for co-production of electricity. We develop a non...
article 2017
document
Milanés, V. (author), Alonso, J. (author), Bouraoui, L. (author), Ploeg, J. (author)
This paper describes the results of vehicle-to-vehicle (V2V) and infrastructure-to-vehicle (I2V) experiments implementing cooperative maneuvering for three different vehicles driving automatically. The cars used were cybercars from the Institut National de Recherche en Informatique et Automatique (INRIA), (France), which are fully automated road...
article 2011
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van der Bas, J.M.A. (author), Quax, P.H.A. (author), van den Berg, A.C. (author), van Hinsbergh, V.W.M. (author), van Bockel, J.H. (author), Gaubius Instituut TNO (author)
Objective: One of the most life-threatening vascular diseases is rupture of an abdominal aneurysm. The conventional treatment is based on surgical reconstruction. An alternative treatment is endovascular aneurysm repair (EVAR). Despite many advantages, one of the problems of EVAR is endoleakage from deficient healing between the aortic neck and...
article 2002
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Bleichrodt, J.F. (author), Blok, J. (author), Dekker, R.H. (author), Medisch Biologisch Laboratorium TNO (author)
article 1961
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Kooij, R.E. (author), van der Mei, R.D. (author), Yang, R. (author), TNO Informatie- en Communicatietechnologie (author)
Performance modeling of the transport control protocol (TCP) has received a lot of attention over the past few years. The most commonly quoted results are approximate formulas for TCP throughput (Padhye et al. (2000) [1]) and document download times (Cardwell et al. (2000) [2]) which are used for dimensioning of IP networks. However, the...
article 2010
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Pasveer, A. (author), Afdeling Gezondheidstechniek TNO (author)
article 1956
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Ploos van Amstel, M.J. (author), TNO Bouw en Ondergrond (author)
article 2009
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Schuurs, A. (author), de Kroon, J.C.A. (author), TNO Bouw (author)
"Het enige dat je nog moet doen, is zemen. Voor de rest is het huis klaar." Zo omschrijft projectleider ir. J. de Kroon van TNO Bouw de nieuwe, baanbrekende methode van kozijnen plaatsen. Daarbij gaan de kozijnen er niet als eerste in, maar als sluitstuk. Afge-schilderd, beglaasd en mét hang en sluitwerk. Bij een bungalow in Pijnacker werd de...
article 1999
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Vermeulen, A.T. (author), Bousquet, P. (author), Rivier, L. (author), Peylin, P. (author), Ciais, P. (author), Ramonet, M. (author), Haszpra, L. (author), Aalto, T. (author), Chevallier, F. (author), Conway, T.J. (author), Anderson, B.E. (author), Brunke, E.G. (author), Ciattaglia, L. (author), Esaki, Y. (author), Fröhlich, M. (author), Gomez, A. (author), Gomez-Pelaez, A.J. (author), Krummel, P.B. (author), Langenfelds, R.L. (author), Leuenberger, M. (author), Machida, T. (author), Maignan, F. (author), Matsueda, H. (author), Morguí, J.A. (author), Mukai, H. (author), Nakazawa, T. (author), Sawa, Y. (author), Schmidt, M. (author), Steele, L.P. (author), Vay, S.A. (author), Wofsy, S. (author), Worthy, D. (author)
This paper documents a global Bayesian variational inversion of CO2 surface fluxes during the period 19882008. Weekly fluxes are estimated on a 3.75?? ?? 2.5?? (longitudelatitude) grid throughout the 21 years. The assimilated observations include 128 station records from three large data sets of surface CO2 mixing ratio measurements. A Monte...
article 2010
document
Fredriks, A.M. (author), van Buuren, S. (author), Hirasing, R.A. (author), Verloove-Vanhorick, S.P. (author), Wit, J.M. (author), TNO Preventie en Gezondheid (author)
article 2001
document
Vermeulen, H. (author), Visser, R. (author), ter Horst, H. (author), Slager, S. (author)
Het opzetten, onderhouden en verbeteren van arbozorg in een bedrijf gaat niet vanzelf, dat zal een preventiemedewerker snel merken. Terwijl iedereen het ermee eens zal zijn dat je niet ziek van je werk mag worden, is het in de praktijk vaak erg lastig om arbomaatregelen uit te voeren en om de arbozorg naar een meer structureel niveau te tillen...
article 2018
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Nowack, B. (author), David, R.M. (author), Fissan, H. (author), Morris, H. (author), Shatkin, J.A. (author), Stintz, M. (author), Zepp, R. (author), Brouwer, D. (author)
The expected widespread use of carbon nanotube (CNT)-composites in consumer products calls for an assessment of the possible release and exposure to workers, consumers and the environment. Release of CNTs may occur at all steps in the life cycle of products, but to date only limited information is available about release of CNTs from actual...
article 2013
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Volkers, R.J.M. (author), de Jong, A.L. (author), Hulst, A.G. (author), van Baar, B.L.M. (author), de Bont, J.A.M. (author), Wery, J. (author), TNO Kwaliteit van Leven TNO Defensie en Veiligheid (author)
The aim of this study was to assess the cellular response of the solvent-tolerant Pseudomonas putida S12 to toluene as the single effector. Proteomic analysis (two-dimensional difference-in-gel-electrophoresis) was used to assess the response of P. putida S12 cultured in chemostats. This approach ensures constant growth conditions, both in the...
article 2006
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Gelinck, G.H. (author), Heremans, P. (author), Nomoto, K. (author), Anthopoulos, T.D. (author), TNO Industrie en Techniek (author)
Organic thin-film transistors (OTFTs) offer unprecedented opportunities for implementation in a broad range of technological applications spanning from large-volume microelectronics and optical displays to chemical and biological sensors. In this Progress Report, we review the application of organic transistors in the fields of flexible optical...
article 2010
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Snelten, H. (author), te Wierik, E. (author), Veenstra, J. (author), Schaafsma, G. (author)
article 1991
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Dulfer, W.J. (author), Groten, J.P. (author), Govers, H.A.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Polychlorinated biphenyls (PCBs) dissolved in dietary fat are absorbed in the gastrointestinal tract by the enterocytes in combination with the fatty acid proceeding from the lipid hydrolysis in the gut lumen. The effect of fatty acid absorption on the uptake and transport of 14 PCBs in enterocytes was studied using monolayers of the human...
article 1996
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Parnham, M.J. (author), Bogaards, J.J.P. (author), Schrander, F. (author), Schut, M.W. (author), Orešković, K. (author), Mildner, B. (author), TNO Kwaliteit van Leven (author)
PLD-118 is a novel, oral antifungal drug, under development for the treatment of Candida infections. Possible metabolism of PLD-118 by rat, dog and human S9 liver homogenates and inhibition of human cytochrome P450 (CYP) enzymes were investigated. PLD-118 (10 and 100 μm) incubated for 0-60 min with S9 fractions and NADPH was determined by HPLC,...
article 2005
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