document

Ageing and osteoarthritis: Application of gerontological concepts;

te Koppele, J.M. (author), Slagboom, P.E. (author), TNO Preventie en Gezondheid (author)

Osteoarthritis (OA) is a multifac{orial chronic disease with high incidence and prevalence in the elderly. Age is a major 'risk factor' in the occurrence ol OA. ln the populat¡on, few individuals suffer from 'early onset OA'. The maiority of individuals have 'late onset OA', whereas a minority of elderly lacks OA. Such a profile is comparable to...

conference paper 1995

document

Dutch vascular dementia study: Objectives, design, first data

Kluft, C. (author), Grobbee, D.E. (author), Koudstaal, P.J. (author), TNO Preventie en Gezondheid (author)

It has been estimated that vascular lesions or thromboembolic processes are the cause of dementia in 10 to 40ol. of demented pat¡ents. Controversy remains regarding the existence ol a definable category of dementia in which vascular factors are the single or most important etiological factor. ln this study we aim to answer lhe following...

conference paper 1995

document

Urinary collagen crosslinks to monitor bone and cartilage degradation in collagen-induced arthritis in rhesus monkeys

te Koppele, J.M. (author), 't Hart, B.A. (author), Gaubius Instituut TNO (author)

article 1995

document

Normal distribution of a single point-mutation in the factor V gene in patients with severe unstable angina pectoris

Verheggen, P. (author), Slagboom, E. (author), de Maat, M. (author), Haverkate, F. (author), Cats, V.M. (author), Gaubius Instituut TNO (author)

Abstract

article 1995

document

2nd European symposium on feed enzymes; proceedings of ESFE2 Noordwijkerhout, 25-27 October 1995

van Hartingsveldt, W. (author), TNO Kwaliteit van Leven (author)

conference paper 1995

document

Letter to the editor. [Dade R chromogenic _2-antiplasmin assay]

Meijer, P. (author), TNO Preventie en Gezondheid (author)

article 1995

document

Aging and the extracellular matrix of lung tumours

Pendleton, N. (author), Jefferson, M.F. (author), te Koppele, J.M. (author), Horan, M.A. (author), TNO Preventie en Gezondheid (author)

conference paper 1995

document

A prospective follow-up study of apolipoprotein E4 allele and cognitive decline; the Rotterdam study: Abstract

Slooter, A.J.C. (author), Gaubius Instituut TNO (author)

conference paper 1995

document

Hemostatic parameters do not predict restenosis after coronary angioplasty;

Uebis, R. (author), Thompson, S.G. (author), Marzilli, M. (author), Bertina, R.M. (author), vom Dahl, M. (author), Fechtrup, C. (author), Casaccia, M. (author), Pyke, S. (author), Haverkate, F. (author), TNO Preventie en Gezondheid (author)

Abstracts From the 68th Scientific Sessions, Anaheim Convention Center Anaheim, California November 13-16, 1995

article 1995

document

Increased hepatic cholesterol synthesis in mdr2 P-glycoprotein deficient mice with impaired biliary cholesterol and phospholipid secretion

Kuipers, F. (author), Wolters, H. (author), Havinga, R. (author), Vonk, R.J. (author), Princen, H.M.G. (author), Oude Elferink, R.P.J. (author), Groen, A.K. (author), TNO Preventie en Gezondheid (author)

Abstracts From the 68th Scientific Sessions, Anaheim Convention Center Anaheim, California November 13-16, 1995

article 1995

document

Retinoids inhibit the synthesis of apolipoprotein (a) in primary hepatocyte cultures from cynomalgus monkey

Neele, D.M. (author), de Wit, E.C.M. (author), Princen, H.M.G. (author), Gaubius Instituut TNO (author)

Abstract

article 1995

document

Prolonged circulation of tissue-type plasminogen activator in vivo by blocking mannose receptor and low-density-lipoprotein receptor-related protein-mediated liver uptake;

Biessen, E.A.L. (author), Kuiper, J. (author), van Teijlingen, M. (author), Vietsch, H. (author), Bijsterbosch, M.K. (author), Rijken, D.C. (author), van Berkel, T.J.C. (author), Gaubius Instituut TNO (author)

Abstract

article 1995

document

Auxin signal transduction in Arabidopsis thaliana: a nove molecular genetic approach

TNO Voeding (author), van der Kop, D.A.M. (author)

doctoral thesis 1995

document

Grijs en groen. Mogelijkheden en belemmeringen van ouderen voor milieuvriendelijk gedrag

TNO Preventie en Gezondheid (author), Huizing, A. (author), Zaal, K. (author)

report 1995

document

Hormones and growth factors in experimental exocrine pancreatic carcinogenesis: De betekenis van hormonen en groeifaktoren bij het ontstaan van kanker van de exocriene pancreas (met een samenvatting in het Nederlands)

TNO Voeding (author), Visser, C.J.T. (author)

doctoral thesis 1995

document

Intestinal absorption and cleavage of beta-carotene in rat, hamster en human models

Centraal Instituut voor Voedingsonderzoek TNO (author), van Vliet, T. (author)

doctoral thesis 1995

document

Oxidant stress and vulnerability of the basal ganglia

TNO Voeding (author), Sloot, W.N. (author)

doctoral thesis 1995

document

Upper respiratory tract toxicity of mixtures of aldehydes: in vivo and in vitro studies [ Toxiciteit van combinaties van aldehydes in de bovenste luchtwegen : in vivo en in vitro studies ]

TNO Voeding (author), Cassee, F.R. (author)

doctoral thesis 1995

document

Signals mediating ABA action in barley grain

TNO Voeding Centrum voor fytotechnologie (author), Heimovaara-Dijkstra, S. (author)

doctoral thesis 1995

document

Constructive technology assessment and extramural/assistive technology: a strong combination

TNO Preventie en Gezondheid (author), van Boxsel, J.A.M. (author), van Beekum, W.T. (author)

Technology Assessment and Medical Technology Assessment were developed as forms ol policy oriented r-esearch to help pollcy makers taking decis¡ons about technologies with wide ranging societal impacts. They are reactive in the sense thal are used by other parties than the developers to evaluate existing technologies. Several attempts have also...

conference paper 1995