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Masthoff, L.J.N. (author), Blom, W.M. (author), Rubingh, C.M. (author), Klemans, R.J.B. (author), Remington, B.C. (author), Bruijnzeel-Koomen, C.A.F.M. (author), van Hoffen, E. (author), Houben, G.F. (author), Meyer, Y. (author), Pasmans, S.G.M.A. (author), Knulst, A.C. (author)[No abstract available] Chemicals / CAS immunoglobulin E, 37341-29-0; Allergens; Antigens, Plant; Cor a 14 allergen, hazelnut; Cor a 9 protein, hazelnut; Immunoglobulin E; Plant Proteins.article 2018
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Rusli, F. (author), Boekschoten, M.V. (author), Borelli, V. (author), Sun, C. (author), Lute, C. (author), Menke, A.L. (author), van den Heuvel, J. (author), Salvioli, S. (author), Franceschi, C. (author), Müller, M. (author), Steegenga, W.T. (author)Calorie restriction (CR) is a dietary regimen that supports healthy aging. In this study, we investigated the systemic and liver-specific responses caused by a diet switch to a medium-fat (MF) diet in 24-month-old lifelong, CR-exposed mice. This study aimed to increase the knowledge base on dietary alterations of gerontological relevance. Nine...article 2018
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Botschuijver, S. (author), Roeselers, G. (author), Levin, E. (author), Jonkers, D.M. (author), Welting, O. (author), Heinsbroek, S.E.M. (author), de Weerd, H.H. (author), Boekhout, T. (author), Fornai, M. (author), Masclee, A.A. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), Seppen, J. (author), van den Wijngaard, R.M. (author)Background & Aims Visceral hypersensitivity is one feature of irritable bowel syndrome (IBS). Bacterial dysbiosis might be involved in the activation of nociceptive sensory pathways, but there have been few studies of the role of the mycobiome (the fungal microbiome) in the development of IBS. We analyzed intestinal mycobiomes of patients with...article 2017
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Fiamoncini, J. (author), Yiorkas, A.M. (author), Gedrich, K. (author), Rundle, M. (author), Alsters, S.I. (author), Roeselers, G. (author), van den Broek, T.J. (author), Clavel, T. (author), Lagkouvardos, I. (author), Wopereis, S. (author), Frost, G. (author), van Ommen, B. (author), Blakemore, A.I. (author), Daniel, H. (author)Bile acids (BA) are signaling molecules with a wide range of biological effects, also identified among the most responsive plasma metabolites in the postprandial state. We here describe this response to different dietary challenges and report on key determinants linked to its interindividual variability. Healthy men and women (n = 72, 62 ± 8 yr,...article 2017
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- Kong, G. (author), Alais, D. (author), van der Burg, E.D. (author) article 2017
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de Wind, A. (author), Burr, H. (author), Pohrt, A. (author), Hasselhorn, H.M.S. (author), van der Beek, A.J. (author), Rugulies, R. (author)Objectives: The aims of this article are to (1) determine whether and to what extent general perceived health and quality of supervision predict voluntary early retirement pension (VERP) and (2) assess whether quality of supervision modifies the association between general perceived health and VERP. Methods: Employees aged 49–64 years who...article 2017
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Hermus, M.A.A. (author), Hitzert, M. (author), Boesveld, I.I. (author), van den Akker-van Marle, E.M. (author), van Dommelen, P. (author), Franx, A. (author), de Graaf, J.P. (author), van Lith, J.M.M. (author), Steegers, E.E. (author), Wiegers, T.A. (author), van der Pal-de Bruin, K.K. (author)Objectives To compare the Optimality Index of planned birth in a birth centre with planned birth in a hospital and planned home birth for low-risk term pregnant women who start labour under the responsibility of a community midwife. Design Prospective cohort study. Setting Low-risk pregnant women under care of a community midwife and living in a...article 2017
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van Vilsteren, M. (author), Boot, C. (author), Twisk, J.W.R. (author), van Schaardenburg, D. (author), Steenbeek, R. (author), Voskuyl, A.E. (author), Anema, J.R. (author)Purpose: In this manuscript, we evaluated the effectiveness of an intervention programme consisting of integrated care and a participatory workplace intervention on supervisor support, work instability and at-work productivity after 6 months of follow-up among workers with rheumatoid arthritis (RA). Methods: We conducted a randomized controlled...article 2017
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Andersen, L.L. (author), Fishwick, D. (author), Robinson, E. (author), Wiezer, N.M. (author), Mockałło, Z. (author), Grosjean, V. (author)Aim: Workers who are satisfied with their job are the cornerstones of healthy and productive companies. This study investigated factors associated with job satisfaction in the general working population. Methods: From the 2010 round of the Danish Work Environment Cohort Study, currently employed wage earners (N=10,427) replied to questions about...article 2017
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Bekker, C. (author), Fransman, W. (author), Boessen, R. (author), Oerlemans, A. (author), Ottenbros, I.B. (author), Vermeulen, R. (author)Background: Nano-specific inhalation exposure models could potentially be effective tools to assess and control worker exposure to nano-objects, and their aggregates and agglomerates (NOAA). However, due to the lack of reliable and consistent collected NOAA exposure data, the scientific basis for validation of the existing NOAA exposure models...article 2017
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Deziel, N.C. (author), Nuckols, J.R. (author), Jones, R.R. (author), Graubard, B.I. (author), de Roos, A.J. (author), Pronk, A. (author), Gourley, C. (author), Colt, J.S. (author), Ward, M.H. (author)Proximity to facilities emitting polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/F) has been associated with increased risk of non-Hodgkin lymphoma (NHL). There is limited information about whether proximity to industrial sources leads to indoor PCDD/F contamination of homes. We measured carpet dust concentrations (pg/g...article 2017
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Ripken, D. (author), van Avesaat, M. (author), Troost, F.J. (author), Masclee, A.A. (author), Witkamp, R.F. (author), Hendriks, H.F. (author)Background. Activation of the ileal brake by casein induces satiety signals and reduces energy intake. However, adverse effects of intraileal casein administration have not been studied before. These adverse effects may include impaired amino acid digestion, absorption and immune activation. Objective. To investigate the effects of intraileal...article 2017
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Deemter, M.V. (author), Bank, R.A. (author), Vehof, J. (author), Hooymans, J.M.M. (author), Los, L.I. (author)Purpose: To explore factors associated with pentosidine accumulation in the human vitreous. Methods: Vitreous samples were obtained during trans pars plana vitrectomy for macular hole or rhegmatogenous retinal detachment. Patient characteristics included age, gender, and diabetes mellitus. Ocular characteristics included pseudophakia, posterior...article 2017
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Ghosh, M (author), Oner, D. (author), Poels, K. (author), Tabish, A.M. (author), Vlaanderen, J. (author), Pronk, A. (author), Kuijpers, E. (author), Lan, Q. (author), Vermeulen, R. (author), Bekaert, B. (author), Hoet, P.H.M. (author), Godderis, L. (author)This study was designed to assess the epigenetic alterations in blood cells, induced by occupational exposure to multi-wall carbon nanotubes (MWCNT). The study population comprised of MWCNT-exposed workers (n=24) and unexposed controls (n=43) from the same workplace. We measured global DNA methylation/hydroxymethylation levels on the 5th...article 2017
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Kooter, I.M. (author), Grollers-Mulderij, M. (author), Duistermaat, E. (author), Kuper, C.F. (author)Mucilair 3D bronchial airway models, cultured at an air-liquid interface, were exposed to aerosols of copper oxide (CuO) nanoparticles in Vitrocell air exposure modules. Four cell donors, four exposure modules and four exposure concentrations were varied within four different exposure sessions using a statistical experimental design called a...article 2017
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van Gool, A.J. (author), Bietrix, F. (author), Caldenhoven, E. (author), Zatloukal, K. (author), Scherer, A. (author), Litton, J.E. (author), Meijer, G. (author), Blomberg, N. (author), Smith, A. (author), Mons, B. (author), Heringa, J. (author), Koot, W.J. (author), Smit, M.J. (author), Hajduch, M. (author), Rijnders, T. (author), Ussi, A. (author)[No abstract available] Chemicals / CAS Biomarkers.article 2017
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Grimshaw, K. (author), Logan, K. (author), O'Donovan, S. (author), Kiely, M. (author), Patient, K. (author), van Bilsen, J. (author), Beyer, K. (author), Campbell, D.E. (author), Garcia-Larsen, V. (author), Grabenhenrich, L. (author), Lack, G. (author), Mills, C. (author), Wal, J.M. (author), Roberts, G. (author)Recommendations and guidelines on the prevention of food allergy have changed in recent decades. The aim of this review of the current evidence and ongoing studies is to provide a comprehensive and up to date picture of prevention of food allergy for healthcare professionals. The review was undertaken as part of the European Union funded...article 2017
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Ly, V. (author), Roijendijk, L.L.M. (author), Hazebroek, H. (author), Tonnaer, C. (author), Hagenaars, M.A. (author)Freezing is a defensive response to acute stress that is associated with coping and alterations in attentional processing. However, it remains unclear whether individuals in high risk professions, who are skilled at making rapid decisions in emergency situations, show altered threat-induced freezing. Here we investigated the effect of incident...article 2017
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Remington, B.C. (author), Westerhout, J. (author), Campbell, D.E. (author), Turner, P.J. (author)We analyzed reaction threshold data from 352 children undergoing open food challenges to hen's egg or cow's milk, either fresh or extensively heated into a muffin. There was no significant shift in dose-distribution curves due to the baking process, implying that existing threshold data for these allergens can be applied to allergen risk...article 2017
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Toet, A. (author)We have tested whether natural dynamic backgrounds affect perceived facial dominance. Facial evaluation is based on just two fundamental dimensions of facial appearance: valence and dominance. Perceived facial valence has been shown to be biased towards background valence. However, it is currently unknown, if the perception of facial dominance...article 2016