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Veldt, E.A. (author), Vermaire, J.H. (author), van Houtem, C.H.M.M. (author), de Jongh, A. (author)
A disproportionately sensitive gag reflex can hamper adequate dental treatment. Because an evidence-based treatment for this condition is lacking at this moment, a study of patients and success variables for the treatment was carried out. The study was based on the clinical records of and interviews with 40 people who had been treated in a...
article 2018
document
Reijnen, A. (author), Geuze, E. (author), Eekhout, I. (author), Maihofer, A.X. (author), Nievergelt, C.M. (author), Baker, D.G. (author), Vermetten, E. (author)
In order to decrease the risk of developing stress-related disorders after military deployment, biological vulnerability factors should be identified. Neuropeptide Y (NPY) is a peptide neurotransmitter that is associated with modulation of the stress response. Using the data of two longitudinal prospective cohort studies (N = 892 and N = 2427),...
article 2018
document
Huurnink, V. (author)
Van 11 tot 15 juni vindt de Week van de RI&E plaats. Met speciale activiteiten willen onder andere brancheorganisaties, opleiders en arbodiensten ondernemers overtuigen écht aan de slag te gaan met de risico - inventarisatie en - evaluatie. Want dat moet beter, vindt ook Bonny de Vries van steunpunt RI&E.
article 2018
document
Zwaveling-Soonawala, N. (author), Trotsenburg, A.S. (author), Verkerk, P.H. (author)
Context. In central hypothyroidism (CeH) free thyroxine (FT4) concentrations are low while TSH concentrations may be low, normal or even slightly elevated due to reduced bioactivity. Congenital CeH (CCeH) may be isolated or part of multiple pituitary hormone deficiency (MPHD). Objective. To test our hypotheses that (1) TSH concentrations have a...
article 2018
document
Eekhout, I. (author), de Vet, H.C. (author), de Boer, M.R. (author), Twisk, J.W. (author), Heymans, M.W. (author)
Previous studies showed that missing data in multi-item scales can best be handled by multiple imputation of item scores. However, when many scales are used, the number of items will become too large for the imputation model to reliably estimate imputations. A solution is to use passive imputation or a parcel summary score that combine and...
article 2018
document
Schutte, S. (author), Esser, D. (author), Hoevenaars, F.P.M. (author), Hooiveld, G.J.E.J. (author), Priebe, M.G. (author), Vonk, R.J. (author), Wopereis, S. (author), Afman, L.A. (author)
Background: Whole-grain wheat (WGW) is described as nutritionally superior to refined wheat (RW) and thus advocated as the healthy choice, although evidence from intervention studies is often inconsistent. The liver, as the central organ in energy metabolism, might be an important target organ for WGW interventions. Objective: The aim of this...
article 2018
document
Blondel, B. (author), Cuttini, M. (author), Hindori-Mohangoo, A.D. (author), Gissler, M. (author), Logh, M. (author), Prunet, C. (author), Heino, A. (author), Smith, L. (author), van der Pal-de Bruin, K. (author), Macfarlane, A.J. (author), Zeitlin, J. (author)
Objective: to describe how terminations of pregnancy at gestational ages at or above the limit for stillbirth registration are recorded in routine statistics and to assess their impact on comparability of stillbirth rates in Europe. Design: analysis of aggregated data from the Euro-Peristat project. Setting: 29 European countries. Population:...
article 2018
document
de Vet, H.C.W. (author), Mullender, M.G. (author), Eekhout, I. (author)
Objective: The concept of specific agreement (SA) has been proposed for dichotomous outcomes for two or more raters. We aim to extend this concept for variables with more than two ordinal or nominal categories and more than two raters. Study Design and Setting: We used two data sets: four plastic surgeons classifying photographs after breast...
article 2018
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Wetselaar, P. (author), Vermaire, J.H. (author), Visscher, C.M. (author), Lobbezoo, F. (author), Schuller, A.A. (author)
This study, performed in 2013, aimed to assess the prevalence of tooth wear in the Dutch adult population. The prevalence of tooth wear was not only determined for different age groups but also according to gender, socioeconomic status and types of teeth. Results were compared with the outcomes of a previous study in a comparable population in...
article 2018
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Sewdas, R. (author), Tamminga, S.J. (author), Boot, C.R.L. (author), van den Heuvel, S.G. (author), de Boer, A.G. (author), van der Beek, A.J. (author)
Background With the increase of the statutory retirement age, the number of self-employed older workers will most likely increase. Therefore, this study aimed to explore: 1) the differences in self-rated health and work ability of self-employed workers and employees, 1) whether self-employment is associated with better self-rated health and work...
article 2018
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Collins, S.L. (author), McMillan, A. (author), Seney, S. (author), van der Veer, C. (author), Kort, R. (author), Sumarah, M.W. (author), Reid, G. (author)
Perturbations to the vaginal microbiota can lead to dysbiosis, including bacterial vaginosis (BV), which affects a large portion of the female population. In a healthy state, the vaginal microbiota is characterized by low diversity and colonization by Lactobacillus spp., whereas in BV, these species are displaced by a highly diverse population...
article 2018
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Wang, L. (author), van Grieken, A. (author), Yang-Huang, J. (author), Vlasblom, E. (author), L'Hoir, M.P. (author), Boere-Boonekamp, M.M. (author), Raat, H. (author)
BACKGROUND: Increased weight gain during infancy is a risk factor for obesity and related diseases in later life. The aim of the present study was to investigate the association between socioeconomic status (SES) and weight gain during infancy, and to identify the factors mediating the association between SES and infant weight gain. METHODS:...
article 2018
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van der Ploeg, C.P.B. (author), Wins, S. (author), Olthof, M.C. (author), Eekhout, I (author), Verkerk, P.H. (author)
In dit rapport wordt verslag uitgebracht van de evaluatie van de neonatale hielprikscreening (NHS) op adrenogenitaal syndroom (AGS), congenitale hypothyreoïdie (CH), 13 metabole ziekten (MZ), hemoglobinopathie (HbP)1 en cystische fibrose (CF ofwel taaislijmziekte) bij kinderen uit Europees Nederland geboren in 2017. Er wordt een aparte monitor...
report 2018
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Smith, L.K. (author), Hindori-Mohangoo, A.D. (author), Delnord, M. (author), Durox, M. (author), Szamotulska, K. (author), Macfarlane, A. (author), Barros, H. (author), Gissler, M. (author), Blondel, B. (author), Zeitlin, J. (author)
Background. International comparisons of stillbirth allow assessment of variations in clinical practice to reduce mortality. Currently, such comparisons include only stillbirths from 28 or more completed weeks of gestational age, which underestimates the true burden of stillbirth. With increased registration of early stillbirths in high-income...
article 2018
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Iyer, V. (author), Landsmeer, N. (author)
De kinderarts als pleitbezorger voor het recht van het kind om veilig op te groeien: een rol die diep verankerd zit in het DNA van de NVK. Als het aan de commissie Pleitbezorging ligt, zouden kinderartsen die rol nog duidelijker uit mogen dragen. In de rubriek De pleitbezorgers komen verschillende maatschappelijke thema’s aan bod waarin de stem...
article 2018
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Hanemaaijer, R. (author), van de Steeg, E. (author), Bobeldijk, I. (author), Ostendorf, R. (author)
Over the last 4 years, the ERP Organ function on-a-chip evolved from a seed ERP (2015) into a full ERP (in 2016) and is still further growing towards 2018. The program has three use cases: gut-, liver- and lung-function on a chip. In addition nano-detection of biochemical (proteins) was explored.
other 2018
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Wil jij een adequate bijdrage leveren aan het bevorderen van de gezondheid van de jeugd in jouw regio? Verwerf de competenties die je daarvoor nodig hebt in de opleiding jeugdarts KNMG bij TNO. het stelsel voor de jGZ bevindt zich midden in een aantal veranderingen. Van de jeugdarts wordt kritisch meedenken verwacht over de veranderingen en de...
other 2018
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Zarcone, M.C. (author), Duistermaat, E. (author), Alblas, M.J. (author), van Schadewijk, A. (author), Ninaber, D.K. (author), Clarijs, V. (author), Moerman, M.M. (author), Vaessen, D. (author), Hiemstra, P.S. (author), Kooter, I.M. (author)
Harmful effects of diesel emissions can be investigated via exposures of human epithelial cells, but most of previous studies have largely focused on the use of diesel particles or emission sources that are poorly representative of engines used in current traffic. We studied the cellular response of primary bronchial epithelial cells (PBECs) at...
article 2018
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Pronk, A. (author), Stierum, R. (author)
Our health is impacted by the environment we grow up, live, work, sport, sleep and relax in. The combination of exposures during daily activities and over the lifetime constitutes a major risk factor for disease. Many common disorders are closely linked to these exposures ranging from lifestyle factors, to chemical exposures, social interactions...
other 2018
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van Dommelen, P. (author), Ouwehand, L.M. (author), Verkerk, P. (author), de Graaff-Korf, K. (author)
public lecture 2018
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