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Bruil, J. (author), Fekkes, M. (author), Vogels, T. (author), Verrips, G.H.W. (author), TNO Preventie en Gezondheid (author)
book 2004
document
'T Hart, B.A. (author), Vogels, J. (author), Bauer, J. (author), Brok, H.P.M. (author), Blezer, E. (author), TNO Voeding (author)
Early recognition of whether a product has potential as a new therapy for treating multiple sclerosis (MS) relies upon the quality of the animal models used in the preclinical trials. The promising effects of new treatments in rodent models of experimental autoimmune encephalomyelitis (EAE) have rarely been reproduced in patients suffering from...
article 2004
document
Kamphuis, M. (author), Zwinderman, K.A.H. (author), Vogels, T. (author), Vliegen, H.W. (author), Kamphuis, R.P. (author), Ottenkamp, J. (author), Verloove-Vanhorick, S.P. (author), Bruil, J. (author), TNO Preventie en Gezondheid (author)
This study represents the development and validation of a cardiac-specific module of the generic health-related quality of life (HRQoL) instrument, the TAAQOL (TNO/AZL Adult Quality Of Life), for young adults with congenital heart disease (CHD). Items were selected based on literature, an explorative previous study in CHD patients, interviews...
article 2004
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Vogels, A.G.C. (author), Detmar, S.B. (author), Verrips, G.H.W. (author), Vogelaar, J.A. (author)
report 2004
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TNO Preventie en Gezondheid (author), Bruil, J. (author), Fekkes, M. (author), Vogels, T. (author), Verrips, G.H.W. (author)
TNO has a number of questionnaires designed to measure health related quality of life of children, adolescents and young adults. The questionnaires are primarily designed for research, such as clinical trials and evaluation research. We have three different questionnaires: TAPQOL - TNO-AZL Questionnaire for Preschool Children's Health-Related...
other 2004
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TNO Preventie en Gezondheid (author), Fekkes, M. (author), Bruil, J. (author), Vogels, T. (author)
This report is meant as a short manual for the TNO-AZL Preschool Children’s Quality of Life questionnaire (TAPQOL). This short manual should be used in conjunction with the reference data and data entry forms, also provided on the CD. The CD_ROM also provides Dutch, English and French versions of the TAPQOL questionnaires. This short manual...
report 2004
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Lamers, R.-J.A.N. (author), de Groot, J. (author), Spies-Faber, E.J. (author), Jellema, R.H. (author), Kraus, V.B. (author), Verzijl, N. (author), te Koppele, J.M. (author), Spijksma, G.K. (author), Vogels, J.T.W.E. (author), van der Greef, J. (author), van Nesselrooij, J.H.J. (author)
Osteoarthritis (OA), one of the most common diseases among the elderly, is characterized by the progressive destruction of joint tissues. Its etiology is largely unclear and no effective disease-modifying treatment is currently available. Metabolic fingerprinting provides a novel tool for the identification of biomarkers. A metabolic fingerprint...
article 2003
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Reijneveld, S.A. (author), Vogels, A.G.C. (author), Harland, P. (author), Brugman, E. (author), Verhulst, F.C. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author)
article 2003
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Vogels, R. (author), Zuijdgeest, D. (author), van Rijnsoever, R. (author), Hartkoorn, E. (author), Damen, I. (author), de BĂ©thune, M.-P. (author), Kostense, S. (author), Penders, G. (author), Helmus, N. (author), Koudstaal, W. (author), Cecchini, M. (author), Wetterwald, A. (author), Sprangers, M. (author), Lemckert, A. (author), Ophorst, O. (author), Koel, B. (author), van Meerendonk, M. (author), Quax, P. (author), Panitti, L. (author), Grimbergen, J. (author), Bout, A. (author), Goudsmit, J. (author), Havenga, M. (author)
Replication-deficient human adenovirus type 5 (Ad5) can be produced to high titers in complementing cell lines, such as PER.C6, and is widely used as a vaccine and gene therapy vector. However, preexisting immunity against Ad5 hampers consistency of gene transfer, immunological responses, and vector-mediated toxicities. We report the...
article 2003
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Vogels, T. (author), Hosli, E.J. (author), Verrips, G.H.W. (author), Vogelaar, J.A. (author), TNO Preventie en gezondheid (author)
report 2003
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Vogels, T. (author), Reijneveld, S.A. (author), Brugman, E. (author), den Hollander-Gijsman, M. (author), Verhulst, F.C. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author)
Background: An extended re-assessment of the psychometric properties of the LSPPK, an instrument aimed at identifying children with emotional and behavioural problems. Methods: Data came from a national sample in the Netherlands of parents of 1248 children (aged 5-6 years) interviewed by child health professionals (CHP). Data were obtained...
article 2003
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van der Greef, J. (author), Davidov, E. (author), Verheij, E. (author), Vogels, J. (author), van der Heijden, R. (author), Adourian, A.S. (author), Oresic, M. (author), Marple, E.W. (author), Naylor, S. (author), TNO Voeding (author)
bookPart 2003
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Stierum, R. (author), Gaspari, M. (author), Dommels, Y. (author), Ouatas, T. (author), Pluk, H. (author), Jespersen, S. (author), Vogels, J. (author), Verhoeckx, K. (author), Groten, J. (author), van Ommen, B. (author)
Here, we describe a proteomics approach to study protein expression changes in differentiating Caco-2 cells. Caco-2 is a colorectal carcinoma cell line, which upon differentiation loses its tumorigenic phenotype and displays characteristics of mature enterocytes, including brush borders with microvilli. Cells were grown in culture flasks and...
article 2003
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van der Ploeg, C.P.B. (author), Kateman, H. (author), Vogelaar, J.A. (author), Herschderfer, K. (author), Rijpstra, A. (author), Vogels, A.G.C. (author), Verkerk, P.H. (author), TNO Preventie en Gezondheid (author)
report 2003
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't Hart, B.A. (author), Vogels, J.T.W.E. (author), Spijksma, G. (author), Brok, H.P.M. (author), Polman, C. (author), van der Greef, J. (author), Primatencentrum TNO (author)
Proton nuclear magnetic resonance (1H-NMR) spectroscopy in combination with pattern recognition techniques were used to investigate the composition of organic compounds in urines from patients with multiple sclerosis (MS), patients with other neurological diseases (OND) and healthy controls (H). Using a valid animal model of MS, namely the...
article 2003
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Reijneveld, S.A. (author), Vogels, A.G.C. (author), Brugman, E. (author), van Ede, J. (author), Verhulst, F.C. (author), Verloove-Vanhorick, S.P. (author)
Background: Psychosocial problems, such as behavioural, emotional, and educational problems, are highly prevalent among children and adolescents. Early treatment may reduce these problems, if accurately identified. Validated questionnaires may support identification. The aim of this study is to assess the psychometric qualities of such a...
article 2003
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Nederlands instituut voor praeventieve gezondheidszorg TNO (author), Vogels, T. (author), Bruil, J. (author), Koopman, H. (author), Fekkes, M. (author), Verrips, G.H.W. (author)
TERMS OF USE TAPQOL, TACQOL AND TAAQOL questionnaires and related materials on our website, including manuals, normative data and syntaxes come free of charge. No registration is needed. This goes for use by non- or not-for-profit parties. For-profit users need to contact us and negotiate a fee.
report 2003
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Vogels, T. (author), Buitendijk, S.E. (author), Bruil, J. (author), Dijkstra, N.S. (author), Paulussen, T.G.W.M. (author), TNO Preventie en Gezondheid (author)
report 2002
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Kamphuis, M. (author), Vliegen, H.W. (author), Vogels, T. (author), Zwinderman, K.H. (author), van der Wall, E.E. (author), Verloove-Vanhorick, S.P. (author), Ottenkamp, J. (author), TNO Preventie en Gezondheid (author)
Objective: To discuss the need for continuing cardiac surveillance in adults with hemodynamically insignificant congenital cardiac disease. Methods: In 82 patients with mild congenital cardiac malformations, aged from 17 to 32 years, we investigated the subjective health status, the health-related quality of life, any difficulties encountered in...
article 2002
document
Kamphuis, M. (author), Vogels, T. (author), Ottenkamp, J. (author), van der Wall, E.E. (author), Verloove-Vanhorick, S.P. (author), Vliegen, H.W. (author)
Objective: To evaluate job participation, careerrelated problems, and actual job problems in adults with complex congenital heart disease (CHD) compared with adults with mild CHD and reference groups. Design: Cross-sectional study. Setting: Patients were randomly selected from the archives of the Department of Pediatric Cardiology, Leiden...
article 2002
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