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Pouwer, M.G. (author), Pieterman, E.J. (author), Chang, S.C. (author), Olsen, G.W. (author), Verschuren, L. (author), Jukema, J.W. (author), Princen, H.M.G. (author)
Epidemiological studies have reported positive associations between serum perfluorooctanoic acid (PFOA) and total and non-high-density lipoprotein cholesterol (non-HDL-C) although the magnitude of effect of PFOA on cholesterol lacks consistency. The objectives of this study were to evaluate the effect of PFOA on plasma cholesterol and...
article 2019
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Dessers, E. (author), Dhondt, S. (author), Annemans, L. (author), Cambre, B. (author), Kenis, P. (author), Hellings, J. (author), Hermans, K. (author), Nys, H. (author), Vanduijck, D. (author), Vrijhoef, H.J.M. (author), van Hootegem, G. (author)
Conference Abstract. In 2013, a 4-year research project on integrated care in Flanders (Belgium) was launched: “Care Organisation: a Re-Thinking EXpedition in search for Sustainability” (CORTEXS). The multidisciplinary research team focuses on the challenge of how to organize care integration. Numerous studies convincingly demonstrate the need...
article 2017
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Dessers, E. (author), Liever, A. (author), Cambre, B. (author), Dhondt, S. (author), Hellings, J. (author), Hermans, K. (author), Molema, H. (author), Nys, H. (author), van Hootegem, G. (author), Vrijhoef, H.J.M. (author)
Conference abstract of the World Congress on Integrated Care 2, Sydney, 23-25 November 2014.
article 2014
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Tsikas, D. (author), Hanff, E. (author), Bollenbach, A. (author), Kruger, R. (author), Pham, V.V. (author), Chobanyan-Jürgens, K. (author), Wedekind, D. (author), Arndt, T. (author), Jörns, A. (author), Berbée, J.F.P. (author), Princen, H.M.G. (author), Lücke, T. (author), Mariotti, F. (author), Huneau, J.F. (author), Ückert, S. (author), Frölich, J.C. (author), Lenzen, S. (author)
We recently found that renal carbonic anhydrase (CA) is involved in the reabsorption of inorganic nitrite (NO2−), an abundant reservoir of nitric oxide (NO) in tissues and cells. Impaired NO synthesis in the endothelium and decreased NO bioavailability in the circulation are considered major contributors to the development and progression of...
article 2018
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Kranenborg, K. (author)
Recent verscheen het boek Invisible Women van Caroline Criado Perez over hoe alledaagse voorwerpen zijn ontworpen voor mannen en dat dit oncomfortabel en soms zelfs bedreigend kan zijn voor vrouwen. Bijvoorbeeld op kantoor (standaard temperatuur te laag), in het verkeer (crash tests worden gedaan met mannelijke dummy’s) en het ontwerp van...
article 2019
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van Gemert, Y. (author), Kozijn, A.E. (author), Pouwer, M.G. (author), Kruisbergen, N.N.L. (author), van den Bosch, M.H.J. (author), Blom, A.B. (author), Pieterman, E.J. (author), Weinans, H. (author), Stoop, R. (author), Princen, H.M.G. (author), van Lent, P.L.E.M. (author)
Objective: High systemic cholesterol levels have been associated with osteoarthritis (OA) development. Therefore, cholesterol lowering by statins has been suggested as a potential treatment for OA. We investigated whether therapeutic high-intensive cholesterol-lowering attenuated OA development in dyslipidemic APOE*3Leiden.CETP mice. Methods:...
article 2021
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Dhondt, S. (author), van Hootegem, G. (author)
Current thinking in several disciplines (organisational economics, sociology, psychology)about organisations is starting to converge. Organisations are no longer considered a blackbox, adapting to the economic environment as will-less objects. There is a role to play for managers to choose the right organisational model. There is still some...
article 2015
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Dhondt, S. (author), Totterdill, P. (author), van Hootegem, G. (author)
The European Workplace Innovation Network (EUWIN) was created in 2013 at the request of the European Commission (DG GROW). Its goal was to develop and promote the idea of Workplace Innovation at the European level. The European Commission wanted to spread the idea that innovation in companies not only was the result of R&D investments but needed...
article 2019
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Keijser, B.J.F. (author), van den Broek, T.J. (author), Slot, D.E. (author), van Twillert, L. (author), Kool, J. (author), Thabuis, C. (author), Ossendrijver, M. (author), van der Weijden, F.A. (author), Montijn, R.C. (author)
Background: The oral cavity harbors a complex microbial ecosystem, intimately related to oral health and disease. The use of polyol-sweetened gum is believed to benefit oral health through stimulation of salivary flow and impacting oral pathogenic bacteria. Maltitol is often used as sweetener in food products. This study aimed to establish the...
article 2018
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Vooijs, M. (author), Bossen, D. (author), Hoving, J.L. (author), Wind, H. (author), Frings-Dresen, M.H.W. (author)
Background: A guideline for occupational health professionals (OHPs) is developed which provides them with knowledge and skills to optimize their guidance to people with a chronic disease. Objective: Developing a training programme to acquire and apply knowledge and skills provided by the guideline, through a bottom-up approach. Methods: First,...
article 2021
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van Dijk, T. (author), Kater, A. (author), Jansen, M. (author), Dondorp, W.J. (author), Blom, M. (author), Kemp, S. (author), Langeveld, M. (author), Cornel, M.C. (author), van der Pal, S.M. (author), Henneman, L. (author)
Neonatal bloodspot screening (NBS) aims to detect treatable disorders in newborns. The number of conditions included in the screening is expanding through technological and therapeutic developments, which can result in health gain for more newborns. NBS expansion, however, also poses healthcare, ethical and societal challenges. This qualitative...
article 2021
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Hooftman, W.E. (author), van Dam, L.M.C. (author), van Genabeek, J. (author)
Hoe zeker zijn werkenden over hun werk en inkomen in Nederland? Hoe gaan flexwerkers en zzp’ers om met werk- en inkomensonzekerheden? Wat zijn oorzaken van deze onzekerheden en wat draagt bij aan het verkrijgen van meer zekerheid? Deze vragen staan centraal in de vijfde editie van Dynamiek op de Nederlandse Arbeidsmarkt (DNA-V) die TNO en CBS...
article 2020
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Huijs, J.J.J.M. (author), Koppes, L.L.J. (author), Taris, T.W. (author), Blonk, R.W.B. (author)
Purpose The present study investigated the relations between work characteristics, depressive symptoms and duration until full return to work (RTW) among long-term sick-listed employees. This knowledge may add to the development of effective interventions and prevention, especially since work characteristics can be subjected to interventions...
article 2017
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