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van Loon, K. (author), Breteler, M.J.M. (author), van Wolfwinkel, L. (author), Rheineck Leyssius, A.T. (author), Kossen, A.S. (author), Kalkman, C.J. (author), van Zaane, B. (author), Peelen, L.M. (author)
Altered respiratory rate is one of the first symptoms of medical conditions that require timely intervention, e.g., sepsis or opioid-induced respiratory depression. To facilitate continuous respiratory rate monitoring on general hospital wards a contactless, non-invasive, prototype monitor was developed using frequency modulated continuous wave...
article 2016
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Minguillón, M.C. (author), Cirach, M. (author), Hoek, G. (author), Brunekreef, B. (author), Tsai, M. (author), de Hoogh, K. (author), Jedynska, A. (author), Kooter, I.M. (author), Nieuwenhuijsen, M. (author), Querol, X. (author)
Trace and major elements concentrations in PM10 and PM2.5 were measured at 20 sites spread in the Barcelona metropolitan area (1 rural background, 6 urban background, 13 road traffic sites) and at 1 reference site. Three 2-week samples per site and size fraction were collected during 2009 using low volume samplers, adding a total of 120 samples....
article 2014
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Prins, R.G. (author), Pierik, F. (author), Etman, A. (author), Sterkenburg, R.P. (author), Kamphuis, C.B.M. (author), van Lenthe, F.J. (author)
In choosing appropriate buffer sizes to study environmental influences on physical activity, studies are hampered by insufficient insight into the distance elderly travel actively. This study aims at getting insight into the number of trips walked and cycled within various buffer sizes using GPS measures. Data were obtained from the Elderly And...
article 2014
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Eeftens, M. (author), Hoek, G. (author), Gruzieva, O. (author), Mölter, A. (author), Agius, R. (author), Beelen, R. (author), Brunekreef, B. (author), Custovic, A. (author), Cyrys, J. (author), Fuertes, E. (author), Heinrich, J. (author), Hoffmann, B. (author), De Hoogh, K. (author), Jedynska, A. (author), Keuken, M. (author), Klümper, C. (author), Kooter, I. (author), Krämer, U. (author), Korek, M. (author), Koppelman, G.H. (author), Kuhlbusch, T.A.J. (author), Simpson, A. (author), Smit, H.A. (author), Tsai, M.Y. (author), Wang, M. (author), Wolf, K. (author), Pershagen, G. (author), Gehring, U. (author)
BACKGROUND: Negative effects of long-term exposure to particulate matter (PM) on lung function have been shown repeatedly. Spatial differences in the composition and toxicity of PM may explain differences in observed effect sizes between studies. METHODS: We conducted a multicenter study in 5 European birth cohorts - BAMSE (Sweden), GINIplus and...
article 2014
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Fountoukis, C. (author), Butler, T. (author), Lawrence, M.G. (author), Denier van der Gon, H.A.C. (author), Visschedijk, A.J.H. (author), Charalampidis, P. (author), Pilinis, C. (author), Pandis, S.N. (author)
We use a 3-D regional chemical transport model, with the latest advancements in the organic aerosol (OA) treatment, and an updated emission inventory for wood combustion to study the organic aerosol change in response to the replacement of current residential wood combustion technologies with pellet stoves. Simulations show a large decrease of...
article 2014
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Rosman, A.N. (author), Guijt, A. (author), Vlemmix, F. (author), Rijnders, M. (author), Mol, B.W.J. (author), Kok, M. (author)
Objective. External cephalic version (ECV) is a safe and effective intervention that can prevent breech delivery, thus reducing the need for cesarean delivery. It is recommended in national guidelines. These guidelines also mention contraindications for ECV, and thereby restrict the application of ECV. We assessed whether the formulation of...
article 2013
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Frost, G.J. (author), Middleton, P. (author), Tarrasón, L. (author), Granier, C. (author), Guenther, A. (author), Cardenas, B. (author), Denier van der Gon, H. (author), Janssens-Maenhout, G. (author), Kaiser, J.W. (author), Keating, T. (author), Klimont, Z. (author), Lamarque, J.-F. (author), Liousse, C. (author), Nickovic, S. (author), Ohara, T. (author), Schultz, M.G. (author), Skiba, U. (author), Van Aardenne, J. (author), Wang, Y. (author)
article 2013
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de Winkel, K.N. (author), Clément, G. (author), Groen, E.L. (author), Werkhoven, P.J. (author)
Although the mechanisms of neural adaptation to weightlessness and re-adaptation to Earth-gravity have received a lot of attention since the first human space flight, there is as yet little knowledge about how spatial orientation is affected by partial gravity, such as lunar gravity of 0.16. g or Martian gravity of 0.38. g. Up to now twelve...
article 2012
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van Dommelen, P. (author), Schönbeck, Y. (author), van Buuren, S. (author)
article 2012
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de Lange-Brokaar, B.J.E. (author), Ioan-Facsinay, A. (author), van Osch, G.J.V.M. (author), Zuurmond, A.-M. (author), Schoones, J. (author), Toes, R.E.M. (author), Huizinga, T.W.J. (author), Kloppenburg, M. (author)
Objective: Although osteoarthritis (OA) is considered a non-inflammatory condition, it is widely accepted that synovial inflammation is a feature of OA. However, the role of immune cells and their cytokines in OA is largely unknown. This narrative systematic review summarizes the knowledge of inflammatory properties, immune cells and their...
article 2012
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van Blijderveen, M. (author), Bramer, E.A. (author), Brem, G. (author)
To gain insight in the startup of an incinerator, this article deals with piloted ignition. A newly developed model is described to predict the piloted ignition times of wood, PMMA and PVC. The model is based on the lower flammability limit and the adiabatic flame temperature at this limit. The incoming radiative heat flux, sample thickness and...
article 2012
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Lindenburg, P.W. (author), Tempels, F.W.A. (author), Tjaden, U.R. (author), van der Greef, J. (author), Hankemeier, T. (author)
Electroextraction (EE) takes place in a two-phase liquid-liquid system, consisting of an aqueous and an organic phase, where an applied electric field causes ions to be extracted from one phase into the other, to be concentrated close after the liquid-liquid interface. The extraction takes place in a wide-bore capillary that is connected to a 2...
article 2012
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Wopereis, S. (author), Radonjic, M. (author), Rubingh, C. (author), van Erk, M. (author), Smilde, A. (author), van Duyvenvoorde, W. (author), Cnubben, N. (author), Kooistra, T. (author), van Ommen, B. (author), Kleemann, R. (author)
The prevalence of diabetes mellitus Type 2 could be significantly reduced by early identification of subjects at risk, allowing for better prevention and earlier treatment. Glucose intolerance (GI) is a hallmark of the prediabetic stage. This study aims at identifying 1) prognostic biomarkers predicting the risk of developing GI later in life...
article 2012
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Jacobs, J.H. (author), Fuertes, E. (author), Krop, E.J.M. (author), Spithoven, J. (author), Tromp, P. (author), Heederik, D.J.J. (author)
Objectives: To describe associations among swimming, respiratory health, allergen sensitisation and Clara cell protein 16 (CC16) levels in Dutch schoolchildren. Trichloramine levels in swimming pool air were determined to assess potential exposure levels. Methods: Respiratory health and pool attendance information was collected from 2359...
article 2012
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Mariman, R. (author), Kremer, S.H.A. (author), van Erk, M. (author), Lagerweij, T. (author), Koning, F. (author), Nagelkerken, L. (author)
Background: Host-microbiota interactions in the intestinal mucosa play a major role in intestinal immune homeostasis and control the threshold of local inflammation. The aim of this study was to evaluate the efficacy of probiotics in the recurrent trinitrobenzene sulfonic acid (TNBS)-induced colitis model and gain more insight into protective...
article 2012
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Banzhaf, S. (author), Schaap, M. (author), Kerschbaumer, A. (author), Reimer, E. (author), Stern, R. (author), van der Swaluw, E. (author), Builtjes, P. (author)
The Chemistry Transport Model REM-Calgrid (RCG) has been improved by implementing an enhanced description of aqueous-phase chemistry and wet deposition processes including droplet pH. A sensitivity study on cloud and rain droplet pH has been performed to investigate its impact on model sulphate production and gas wet scavenging. Air...
article 2012
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Reus, A.A. (author), Usta, M. (author), Kenny, J.D. (author), Clements, P.J. (author), Pruimboom-Brees, I. (author), Aylott, M. (author), Lynch, A.M. (author), Krul, C.A.M. (author)
An in vivo photomicronucleus test (MNT) using rat skin, the target organ for photoirritancy and carcinogenicity, was recently described. The assay was evaluated using fluoroquinolone (FQ) antibiotics with varying degrees of phototoxic potency (i.e. sparflocacin [SPFX], lomefloxacin [LOFX], ciprofloxacin [CIFX], levofloxacin [LEFX], gemifloxacin ...
article 2012
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Stomp-van den Berg, G.M. (author), Hendriksen, I.J.M. (author), Bruinvels, D.J. (author), Twisk, J.W.R. (author), van Mechelen, W. (author), van Poppel, M.N.M. (author)
The objective of this study was to examine which factors during pregnancy and postpartum predict pelvic girdle pain (PGP) at 12 weeks postpartum among working women. A total of 548 Dutch pregnant employees were recruited in 15 companies, mainly health care, child care, and supermarkets. The definition of PGP was any pain felt in the pelvic...
article 2012
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Alapaty, K. (author), Mathur, R. (author), Pleim, J. (author), Hogrefe, C. (author), Rao, S.T. (author), Ramaswamy, V. (author), Galmarini, S. (author), Schaap, M. (author), Makar, P. (author), Vautard, R. (author), Baklanov, A. (author), Kallos, G. (author), Vogel, B. (author), Sokhi, R. (author)
article 2012
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Vos, P.A.J.M. (author), Degroot, J. (author), Barten-Van Rijbroek, A.D. (author), Zuurmond, A.-M. (author), Bijlsma, J.W.J. (author), Mastbergen, S.C. (author), Lafeber, F.P.J.G. (author)
Osteoarthritis is a highly prevalent disease, age being the main risk factor. The age-related accumulation of advanced-glycation-endproducts (AGEs) adversely affects the mechanical and biochemical properties of cartilage. The hypothesis that accumulation of cartilage AGEs in combination with surgically induced damage predisposes to the...
article 2012
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