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document
Walraven, P.L. (author), Instituut voor Zintuigfysiologie TNO (author)
THE Stiles–Crawford effect1,2, or the dependence of luminous efficiency on the eccentricity of the point of entry of the light in the pupil, is a function of the wavelength of the light. In Fig. 1 is given the inverse 1/ of the luminous efficiency as a function of wave-length at a distance of 3.5 mm from the point of maximum efficiency,...
article 1966
document
Vos, J.J. (author), Walraven, P.L. (author), Instituut voor Zintuigfysiologie TNO (author)
To derive the fundamental response curves for the three colour mediating systems from the location of the dichromatic confusion centres, one must make certain assumptions on the nature of dichromatism. It is shown, however, that one can avoid to make specific quantitative assumptions by bringing into the picture other visual data, such as the...
article 1971
document
Bouman, M.A. (author), Walraven, P.L. (author), Instituut voor Zintuigfysiologie TNO (author)
On the basis of measurements of the achromatic zone for red light in the fovea and for green light in the periphery, a discussion is given on the possible difference in threshold mechanisms for the achromatic (scotopic) and chromatic (photopic) retinal systems. A specific suggestion for this distinction is given that not directly refers to the...
article 1972
document
Bunt, A.A. (author), Sanders, A.F. (author)
An experiment is reported on the effects of cognitive similarity on proactive and retroactive interference (PI, RI) in short term memory. To avoid confounding between cognitive and acoustic similarity, the materials - i.e. words and digits - were matched with respect to vowel pattern. Effects of both PI and RI were found on recall of words,...
article 1972
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Germans, F.H. (author), Koster, M.W. (author), Kwee, H.H. (author), Groep Motoriek Revalidatie, Medisch Fysisch Instituut TNO Instituut voor gezondheidstechniek TNO (author)
The merits of the 'vacuum form fixation' are discussed for the production of reliable body impressions of patients suffering from sitting problems. Impressions are taken with the patients seated in the desired posture. The first results are reported, obtained from 4 patients of different categories, fitted with individually moulded seats...
article 1974
document
Bunt, A.A. (author)
Thirty-two subjects had tests of serial recall of visually presented nine-digit lists which were either presented in a single block of trials (constant context) or in between lists of much longer length (variable context). Other variables were vocalization-during-presentation versus silent memorization (within subject) and order of recall ...
article 1976
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Nieuwenhuizen, W. (author), Voskuilen, M. (author), Hermans, J. (author), Gaubius instituut TNO (author)
The present study was undertaken as a step to delineate further the localization of the calcium-binding sites in fibrinogen and to assess the anticlotting properties of fibrinogen degradation products. To this purpose, fragments Y were prepared by plasmin digestion of human fibrinogen in the presence of added Ca2+, and purified. We found that,...
article 1982
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Verheijen, J.H. (author), Nieuwenhuizen, W. (author), Wijngaards, G. (author), Gaubius instituut TNO (author)
Tissue activator-mediated plasminogen activation is potentiated both by fibrin and by some soluble fibrin(ogen) fragments. The potentiating effect of the different fragments decreases in the order fibrin monomer > D-dimer > Y > D EGTA > Dcate > X. Fibrinogen and the fragments Ecate, E EGTA and E fibrin have almost no effect. The existence of a...
article 1982
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Nieuwenhuizen, W. (author), Haverkate, F. (author), Gaubius Instituut TNO (author)
Chemicals/CAS: fibrinogen, 9001-32-5; calcium, 7440-70-2; Calcium, 7440-70-2; Fibrinogen, 9001-32-5
article 1983
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van Hinsbergh, V.W.M. (author), Havekes, L. (author), Emeis, J.J. (author), van Corven, E. (author), Scheffer, M. (author), Gaubius Instituut TNO (author)
Binding and metabolism of low density lipoprotein (LDL) and acetylated LDL were examined in endothelial cells from human umbilical cord arteries and veins. Both high and low affinity LDL interactions were observed. High affinity LDL binding and catabolism were increased five- to sevenfold after preincubation for 18 hours in LPDS containing...
article 1983
document
Gaubius instituut TNO (author), Havekes, L. (author), van Hinsbergh, V. (author), Kempen, H.J. (author), Emeis, J. (author)
The human hepatoma cell line Hep G2 was studied with respect to metabolism of human low-density lipoprotein (LDL). The Hep G2 cells bind, take up and degrade human LDL with a high-affinity saturable and with a low-affinity non-saturable component. The high-affinity binding possesses a K(D) of 25 nM-LDL and a maximal amount of binding of about 70...
article 1983
document
Haverkate, F. (author), Nieuwenhuizen, W. (author), Gaubius Instituut TNO (author)
Chemicals/CAS: calcium chloride, 10043-52-4; calcium, 7440-70-2; citric acid, 126-44-3, 5949-29-1, 77-92-9, 8002-14-0; edetic acid, 150-43-6, 60-00-4
article 1984
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Verheijen, J.H. (author), Chang, G.T.G. (author), Kluft, C. (author), Gaubius Instituut TNO (author)
Human plasma contains a fast-acting t-PA inhibitor, which is not identical with ??2-antiplasmin or ??2-macroglobulin. The concentration of this inhibitor in normal plasma is highly variable, much lower than that of known plasma protease inhibitors, and in the range of physiologically occurring plasma concentrations of t-PA (0-2 IU/ml). The...
article 1984
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Haverkate, F. (author), Koopman, J. (author), Koppert, P. (author), Nieuwenhuizen, W. (author), Gaubius Institute, Health Research Division TNO, 2313 AD Leiden, Netherlands (author)
article 1985
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Kluft, C. (author), Jie, A.F.H. (author), Sprengers, E.D. (author), Verheijen, J.H. (author), Gaubius Instituut TNO (author)
Inhibition of tissue-type plasminogen activator (t-PA) by pooled plasma could be ascribed for only 60% to the endothelial cell type PA inhibitor. The residual inhibition is ascribed to a so-far undescribed plasma component present at 0.2 nmol/l. This component shows reversible binding to t-PA with an apparent K(i) of 10 pmol/l (does not hinder t...
article 1985
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Pikaar, N.A. (author), Wedel, M. (author), van der Beek, E.J. (author), van Dokkum, W. (author), Kempen, H.J.M. (author), Kluft, C. (author), Ockhuizen, T. (author), Hermus, R.J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
To investigate the effect of moderate alcohol consumption on blood constituents related to cardiovascular disease, 12 male volunteers consumed (instead of their usual alcoholic drinks) four different standardized amounts of red wine in addition to their habitual diet. Each dose was given to the subjects during a period of 5 weeks in a randomized...
article 1987
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Janssen, W.H. (author), Tenkink, E. (author), Instituut voor Zintuigfysiologie TNO (author)
Risk-taking behavior by drivers is put within the context of a general model of utility maximization by speed choice. It is shown that so-called "risk homeostasis" is possible only under very restrictive conditions. Under more general conditions, risk compensation can occur; that is, the safety effects expected from engineering measures will be...
article 1988
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Riemersma, J.B.J. (author), Instituut voor Zintuigfysiologie TNO (author)
Driver behaviour will partially be a function of the cognitive schemata by which drivers represent features, functions and operations of traffic system components. This paper uses the Repertory Grid Technique to address the questions: (1) How do drivers internally represent different categories of road? (2) How are those representations mapped...
article 1988
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Godthelp, J. (author), Käppler, W.D. (author), Instituut voor Zintuigfysiologie TNO (author)
The time-to-line-crossing (TLC) concept has been used as a time-related measure to describe driving strategy. The purpose of this research is to analyze whether TLC might enlarge our understanding of the relationship between vehicle handling characteristics and a driver's looking and lateral control strategy in a straight-lane-keeping task....
article 1988
document
Miedema, H.M.E. (author), Ham, J.M. (author)
Odour exposures were determined by odour emission measurements and dispersion calculations. Odour annoyance was determined by a social survey. The relation between the odour concentration that is exceeded during 2 per cent of the year preceding the interviews, and the percentage 'annoyed' plus 'very annoyed' is presented.
article 1988
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