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Instituut CIVO-Toxicologie en voeding TNO (author), van Dokkum, W. (author), Wesstra, A. (author), Luyken, R. (author), Hermus, R.J.J. (author)
Twelve young men were given for periods of 20 d, each of three mixed diets, namely a low-protein (LP) diet (9% total energy as protein, 67% of animal origin), a high-animal-protein (HA) diet (16% total energy as protein, 67% of animal origin) and a high-vegetable-protein (HV) diet (16% total energy as protein, 67% of vegetable origin). Retention...
article 1986
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van Dokkum, W. (author), Schrijver, J. (author), Wesstra, J.A. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
The biological variability of the values of various biochemical indices used for the assessment of the nutritional status of man was investigated in 4 healthy male volunteers (mean age 23 years). They were given a constant diet for 60 d, with the nutrient intake at the level of the Dutch recommendations. Blood was collected twice a week and 24-h...
article 1990
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Centraal Instituut voor Voedingsonderzoek TNO (author), Torre H.W.van der, (author), van Dokkum, W. (author), Schaafsma, G. (author), Wedel, M. (author), Ockhuizen, T. (author)
After a 5-week period of low selenium intake, twenty-four Dutch men received 55, 135 or 215 ug Se/d as Se-rich meat or bread for a 9-week period. Four unsupplemented subjects served as controls. Plasma Se increased more rapidly than erythrocyte Se levels; the increases were significantly dependent (P < 0.001) on Se intake level. Glutathione...
article 1991
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Velthuis-te Wierik, E.J.M. (author), Westerterp, K.R. (author), van den Berg, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: Since little information is available on the capacity of the non-obese to adapt to a moderate decrease in energy intake, the effect of a 10-week moderately energy-restricted diet (ER) on energy expenditure and body composition was studied. Design: A controlled intervention study. After a weight-maintaining run-in period of 2 weeks,...
article 1995
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van Vliet, T. (author), Schreurs, W.H.P. (author), van den Berg, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Postprandial response curves of β-carotene and retinyl esters in a triglyceride-rich lipoprotein (TRL) fraction were evaluated as a potential measure of β-carotene uptake and cleavage. β-Carotene, retinyl ester, and triglyceride concentrations in the TRI, fraction (density < 1.006 kg/L) and plasma were measured in 10 men for 8 or 16 h after an...
article 1995
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Brussaard, J.H. (author), Hulshof, K.F.A.M. (author), Löwik, M.R.H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
To estimate the effect of possible goitre prophylactic measures on the intake of iodine among population groups, simulation studies, based on the first Dutch National Food Consumption Survey, were carried out. Iodine intake figures and prevalence of low intakes were calculated after fictively iodizing either bread, a combination of industrial...
article 1995
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Velthuis-te Wierik, E.J.M. (author), van Leeuwen, R.E.W. (author), Hendriks, H.F.J. (author), Verhagen, H. (author), Loft, S. (author), Poulsen, H.E. (author), van den Berg, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Restriction of energy intake (ER), without malnutrition of essential nutrients, has repeatedly been demonstrated to increase longevity in rodents. In the antioxidant theory of aging the lack of balance between the generation of free radicals and free radical scavenging was thought to be a main causal agent in the aging process. From this point...
article 1995
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van Poppel, G. (author), Poulsen, H. (author), Loft, S. (author), Verhagen, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
article 1995
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Brussaard, J.H. (author), van Dokkum, W. (author), van der Paauw, C.G. (author), de Vos, R.H. (author), de Kort, W.L.A.M. (author), Löwik, M.R.H. (author), TNO Voeding (author)
To assess the level of exposure to food contaminants (cadmium, lead, PCBs, DDT, hexachlorobenzene, nitrate and malathion) a total-diet study was carried out. A total of 226 food products were analysed individually; the concentration of contaminants in products not selected for analysis was estimated with the help of published data. The results...
article 1996
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Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.O. (author), Beeson, L. (author), van den Brandt, P.A. (author), Folsom, A.R. (author), Fraser, G.E. (author), Goldbohm, R.A. (author), Graham, S. (author), Howe, G.R. (author), Kushi, L.H. (author), Marshall, J.R. (author), Mcdermott, A. (author), Miller, A.B. (author), Speizer, F.E. (author), Wolk, A. (author), Yaun, S.S. (author), Willett, W. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Background. Experiments in animals, international correlation comparisons, and case-control studies support an association between dietary fat intake and the incidence of breast cancer. Most cohort studies do not corroborate the association, but they have been criticized for involving small numbers of cases, homogeneous fat intake, and...
article 1996
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Schifferstein, H.N.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The Equiratio Mixture Model predicts the psychophysical function for an equiratio mixture type on the basis of the psychophysical functions for the unmixed components. The model reliably estimates the sweetness of mixtures of sugars and sugar-alchohols, but is unable to predict intensity for aspartame/sucrose mixtures. In this paper, the...
article 1996
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Rompelberg, C.J.M. (author), Vogels, J.T.W.E. (author), de Vogel, N. (author), Bruijntjes-Rozier, G.C.D.M. (author), Stenhuis, W.H. (author), Bogaards, J.J.P. (author), Verhagen, H. (author), TNO Voeding (author)
1. In order to study the antigenotoxic potential of eugenol in humans, ten healthy non-smoking males ingested a daily amount of 150 mg eugenol or the placebo for seven consecutive days. After a washout period of one week, groups ingesting eugenol or the placebo were crossed and received the other treatment for seven consecutive days. 2. On days...
article 1996
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Verhagen, H. (author), Rauma, A.L. (author), Törrönen, R. (author), de Vogel, N. (author), Bruijntjes-Rozier, G.C.D.M. (author), Dreve, M.A. (author), Bogaards, J.J.P. (author), Mykkänen, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
1. In order to study the potential beneficial effects of a vegan diet, a cross-sectional study was performed and several biomarkers of chemoprevention were measured in a population of female 'living food' eaters ('vegans'; n = 20) vs matched omnivorous controls (n = 20). 2. White blood cells obtained from fresh blood samples were subjected to...
article 1996
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Muijser, H. (author), Geuskens, R.B.M. (author), Hooisma, J. (author), Emmen, H.H. (author), Kulig, B.M. (author), TNO Voeding (author)
Carpet layers and age-matched controls were investigated both at the beginning of a working day and at the end with four subtests of a neuropsychological test battery (NES2). Exposure to toluene, cyclohexane, ethyl acetate, and heptane was measured with personal air sampling methods. One group of carpet layers used water-based adhesives (WBA) on...
article 1996
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van 't Veer, P. (author), Strain, J.J. (author), Fernandez-Crehuet, J. (author), Martin, B.C. (author), Thamm, M. (author), Kardinaal, A.F.M. (author), Kohlmeier, L. (author), Huttunen, J.K. (author), Martin-Moreno, J.M. (author), Kok, F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Antioxidants may protect against free radical mediated carcinogenesis. Epidemiological studies have not confirmed this hypothesis for breast cancer, possibly because of methodological limitations. Time-integrated exposure of α-tocopherol and β-carotene in adipose tissue, and selenium in toenails was investigated in a case-control study among...
article 1996
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van den Berg, H. (author), Hulshof, K.F.A.M. (author), Deslypere, J.P. (author), TNO Voeding (author)
Objective. To determine how much vitamin A is consumed through liver and liver products by non-pregnant and pregnant women aged 16-50 years, and to determine the implications for the use of multivitamin products. Design. Secondary analysis on data from representative database Dutch National Food Consumption Survey. Method. Data were obtained...
article 1996
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te Velthuis- Wierik, E.J.M. (author), van den Berg, H. (author), Weststrate, J.A. (author), van het Hof, K.H. (author), de Graaf, C. (author), TNO Voeding (author)
Objective: Dietary fat intake is higher than recommended in most western countries and is associated with the prevalence of cardiovascular diseases, obesity and cancer. The growing public concern about the adverse effects of a high fat intake has led to an increased availability of 'reduced-fat' products. Consumption of reduced-fat products...
article 1996
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van den Berg, H. (author), Hulshof, K.F.A.M. (author), Deslypere, J.P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To assess the distribution of dietary vitamin A intake among Dutch women aged 16-50 and among pregnant women, and to evaluate the effect of the use of a vitamin A (1200 RE) containing multivitamin supplement in terms of nutritional and teratogenic risk. Study design: Data from the 2nd Dutch national food consumption survey (1992) were...
article 1996
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Löwik, M.R.H. (author), TNO Voeding (author)
Several methods can be and are being used to assess individual food consumption. Four types, namely 24-h recall, dietary records, food frequency and dietary history are discussed. For assessing the exposure to additives it is concluded that the dietary history method is probably the best choice since this method is oriented towards a...
article 1996
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van Dokkum, W. (author), van Boxtel, L.B.J. (author), van Dijk, M.J. (author), Boer, L.C. (author), van der Beek, E.J. (author), TNO Voeding TNO Technische Menskunde (author)
Background: The increased threat of nuclear, biological and chemical (NBC) weapons underlines the need of protective clothing and gas masks, but this may impair performance. Thus, attention should be focused on the nutritional requirements. Hypothesis: Optimal performance is guaranteed if the supply of water and energy is adequate. Methods: Two...
article 1996
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