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Wins, S. (author), van der Ploeg, C.P.B. (author), Verkerk, P.H. (author)
The Newborn Blood Spot screening programme (NBS) was introduced in the Netherlands in 1974. The programme is coordinated by the Centre for Population Screening (CvB) of the National Institute for Public Health and the Environment (RIVM). The aim of the NBS is the early detection of a number of serious congenital diseases in newborns. Children...
report 2021
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Bouva, M. (author), Heijnen, M.L. (author), Jacobs, B. (author), van der Ploeg, C.P.B. (author), Gille, J. (author), Gulmans, V. (author), Verschoof-Puite, R. (author), de Winter-de Groot, K. (author)
public lecture 2021
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Stroek, K. (author), Heijboer, A.C. (author), Bouva, M.J. (author), van der Ploeg, C.P.B. (author), Heijnen, M.L.A. (author), Weijman, G. (author), Bosch, A.M. (author), de Jonge, R. (author), Schielen, P.C.J.I. (author), van Trotsenburg, A.S.P. (author), Boelen, A. (author)
Objective: Congenital hypothyroidism (CH) is defined as thyroid hormone deficiency at birth due to disorders of the thyroid gland (thyroidal CH, CH-T), or the hypothalamus or pituitary (central CH, CH-C). The Dutch Newborn Screening (NBS) strategy is primarily based on determination of thyroxine (T4) concentrations in dried blood spots followed,...
article 2020
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van Groen, B.D. (author), van de Steeg, E. (author), Mooij, M.G. (author), van Lipzig, M.M.H. (author), de Koning, B.A.E. (author), Verdijk, R.M. (author), Wortelboer, H.M. (author), Gaedigk, R. (author), Bi, C. (author), Leeder, S. (author), van Schaik, R.H.N. (author), van Rosmalen, J. (author), Tibboel, D. (author), Vaes, W.H. (author), de Wildt, S.N. (author)
Background Hepatic membrane transporters are involved in the transport of many endogenous and exogenous compounds, including drugs. We aimed to study the relation of age with absolute transporter protein expression in a cohort of 62 mainly fetus and newborn samples. Methods Protein expressions of BCRP, BSEP, GLUT1, MCT1, MDR1, MRP1, MRP2, MRP3,...
article 2018
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Schönbeck, Y. (author), Olthof, R. (author), van der Ploeg, K. (author), Verkerk, P.H. (author)
The Newborn Blood Spot screening program (NBS) was introduced in the Netherlands in 1974. The program is coordinated by the Centre for Population Screening (CvB) of the National Institute for Public health and the Environment (RIVM). The aim of the NBS is the early detection of certain serious congenital disorders in newborns. Children with...
report 2017
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van Ganzewinkel, C.J. (author), Been, J.V. (author), Verbeek, I. (author), Boelen-van der Loo, T. (author), van der Pal, S.M. (author), Kramer, P.W. (author), Andriessena, P. (author)
Background. Data on long-term consequences of neonatal pain is limited. Aim. To assess whether perinatal factors, later pain experience and pain coping strategies are associated with altered pain threshold, pain tolerance and pain intensity in adolescents born preterm. Study design. Observational, longitudinal study (Project on Preterm and SGA...
article 2017
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van Ganzewinkel, C.J. (author), Been, J.V. (author), Dielemane, J.P. (author), Katgert, T. (author), Boelen-van der Loo, T. (author), van der Pal, S.M. (author), van Dijk, M. (author), Kramer, P.W. (author), Andriessena, P. (author)
Background Data on long-term consequences of preterm birth on pain coping later in life are limited. Aim The aim of this study was to assess whether gestational age, birth weight and neonatal disease severity have an effect on the pain coping strategy in adolescents born preterm or with low birth weight. Study design Observational, longitudinal...
article 2016
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van der Ploeg, C.P.B. (author), van den Akker-van Marle, M.E. (author), Vernooij-van Langen, A.M.M. (author), Elvers, L.H. (author), Gille, J.J.P. (author), Verkerk, P.H. (author), Dankert-Roelse, J.E. (author), Loeber, J.G. (author), Triepels, R.H. (author), van der Pal, S.M. (author), Dompeling, E. (author), Pals, G. (author), Gulmans, V.A.M. (author), Oey-Spauwen, M.J.W. (author), Wijnands, Y.H.H.M. (author), Castricum, L.M. (author), Arets, H.G.M. (author), van der Ent, C.K. (author), Tiddens, H.A.W.M. (author), de Rijke, Y.B. (author), Yntema, J.B. (author)
BACKGROUND: Previous cost-effectiveness studies using data from the literature showed that newborn screening for cystic fibrosis (NBSCF) is a good economic option with positive health effects and longer survival. METHODS: We used primary data to compare cost-effectiveness of four screening strategies for NBSCF, i.e. immunoreactive trypsinogen...
article 2015
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Alberts, N. (author), Beerling, M. (author), Benschop, K. (author)
The 2014-2015 report presents the following findings: As in previous years, the vaccination coverage among newborns was more than 94%; The vaccination coverage against human papillomavirus (HPV), which can cause cervical cancer, among 12-year-old girls was increased to 61%; The number of reports of pertussis was higher than in 2013, but not as...
report 2015
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Hayes, D.J. (author), van Buuren, S. (author), ter Kuile, F.O. (author), Stasinopoulos, D.M. (author), Rigby, R.A. (author), Terlouw, D.J. (author)
Methods: A weight-for-age database was constructed from pre-existing population-based anthropometric data obtained from household surveys and research groups. It contained data collected between 1995 and 2012 on 1 263 119 individuals (909 368 female, 353 751 male) older than 14 days and younger than 50 years in 64 malaria-endemic countries....
article 2015
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Turner, M.A. (author), Mooij, M.G. (author), Vaes, W.H.J. (author), Windhorst, A.D. (author), Hendrikse, N.H. (author), Knibbe, C.A.J. (author), Körgvee, L.T. (author), Maruszak, W. (author), Grynkiewicz, G. (author), Garner, R.C. (author), Tibbocl, D. (author), Park, B.K. (author), de Wildt, S.N. (author)
Important information gaps remain on the efficacy and safety of drugs in children. Pediatric drug development encounters several ethical, practical, and scientifîc chaflenges One barrier to the evaluation of medicines for children is a lack of Innovative methodologies that have been adapted to the needs of chiIdren This article presents our...
article 2015
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van Dommelen, P. (author), Verkerk, P.H. (author), van Straaten, H.L. (author)
Objective To gain insight into health and related costs associated with very preterm births, one needs accurate information about the prevalence of the disabling conditions, including neonatal hearing loss (NHL). Study design We assessed the prevalence of NHL by week of gestation and categories of birth weight in very preterm neonates. Results...
article 2015
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Zwaveling-Soonawala, N. (author), Trotsenburg, A.S. (author), Verkerk, P.H. (author)
Congenital hypothyroidism (CH) may be of thyroidal (CHT) or central origin (CHC). Worldwide, most neonatal screening programs are TSH based and effectively detect CHT. Only a few screening programs measure total or free T4 and TSH simultaneously or stepwise, enabling detection of CHT as well as CHC. A frequently used argument against screening...
article 2015
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van der Pal-de Bruin, K.M. (author), Heerdink, N. (author), Kamphuis, M. (author), Pols, M.A. (author)
Conflict of interest and financial support: disclosure forms provided by the authors are available along with the full text of this article at www.ntvg.nl, search for A6745; click on ‘Belangenverstrengeling’ (‘Conflict of interest’). The Netherlands Organization for Health Research and Development provided a subsidy (subsidy no 156000009) to the...
article 2014
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MacDorman, M.F. (author), Mathews, T.J. (author), Mohangoo, A.D. (author), Zeitlin, J. (author)
OBJECTIVES: This report investigates the reasons for the United States' high infant mortality rate when compared with European countries. Specifically, the report measures the impact on infant mortality differences of two major factors: the percentage of preterm births and gestational age-specific infant mortality rates. METHODS: Infant...
article 2014
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Mooij, M.G. (author), van Duijn, E. (author), Knibbe, C.A.J. (author), Windhorst, A.D. (author), Hendrikse, N.H. (author), Vaes, W.H.J. (author), Spaans, E. (author), Fabriek, B.O. (author), Sandman, H. (author), Grossouw, D. (author), Hanff, L.M. (author), Janssen, P.J.J.M. (author), Koch, B.C.P. (author), Tibboel, D. (author), de Wildt, S.N. (author)
Results: Ten infants (aged 0.1–83.1 months) were included; one was excluded as he vomited shortly after administration. In nine patients, [14C]AAP and metabolites in blood samples were detectable at expected concentrations: median (range) maximum concentration (Cmax) [14C]AAP 1.68 (0.75–4.76) ng/L, [14C]AAP-Glu 0.88 (0.34–1.55) ng/L, and [14C...
article 2014
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Harb, H. (author), van Tol, E.A.F. (author), Heine, H. (author), Braaksma, M. (author), Gross, G. (author), Overkamp, K. (author), Hennen, M. (author), Alrifai, M. (author), Conrad, M.L. (author), Renz, H. (author), Garn, H. (author)
Background: Oral supplementation with probiotic bacteria can protect against the development of allergic and inflammatory diseases. Objective: The aim of this study was to investigate potential immunomodulatory and allergy-protective effects of processed Lactobacillus rhamnosus GG (LGG)-derived supernatants early in life in neonatal mice....
article 2013
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Deurloo, J.A. (author), van Gameren-Oosterom, H.B.M. (author), Kamphuis, M. (author)
There is a high incidence of skin disorders; these are also frequently encountered within Youth Healthcare (YHC). Some skin disorders are caused by an underlying disease, syndrome or child abuse. Therefore, detection of these causes in an early stage is important. Skin disorders can have a huge psychosocial impact on both child and parents. This...
article 2012
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Schönbeck, Y. (author), Talma, H. (author), van Dommelen, P. (author), Bakker, B. (author), Buitendijk, S.E. (author), HiraSing, R.A. (author), van Buuren, S. (author)
To assess the prevalence of overweight and obesity among Dutch children and adolescents, to examine the 30-years trend, and to create new body mass index reference charts. Design: Nationwide cross-sectional data collection by trained health care professionals. Participants: 10,129 children of Dutch origin aged 0-21 years. Main Outcome Measures:...
article 2011
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van Dommelen, P. (author), van Straaten, H.L.M. (author), Verkerk, P.H. (author)
Aim: To evaluate 10-year quality assurance of newborn hearing screening (NHS) in Dutch neonatal intensive care units (NICU). Methods: Results of the two-stage automated auditory brainstem response (AABR) screening and diagnostic examination in NICU graduates were centrally registered between October 1998 and December 2008. This registration...
article 2011
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