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Small, J. (author), van Hoek, C. (author), van der Does, F. (author), Seinen, A.B. (author), Melzer, S. (author), Tromp, P.C. (author), van der Laan, S. (author)
A method has been developed to screen large numbers (~103–104 per sample) of coarse airborne dust particles for the occurrence of Pb-rich phases, together with quantification of the particles’ mineralogy, chemistry, and inferred provenance. Using SEM-EDS spectral imaging (SI) at 15 kV, and processing with the custom software PARC, screening of...
article 2021
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van Hees, S.G.M. (author), Bouwine, C. (author), Blonk, R.W.B. (author), Oomens, S. (author)
BACKGROUND: Work participation among employees with common mental disorders (CMDs) is an increasingly important, yet highly complex phenomenon. Given the call for preventing instead of reacting to negative work outcomes, there is a need to understand how employees with CMDs can continue working. OBJECTIVES: 1) to provide insights in applying a...
article 2021
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Cacciatore, P. (author), Visser, L.A. (author), Buyukkaramikli, N. (author), van der Ploeg, C.P.B. (author), van den Akker-van Marle, M.E. (author)
Introduction: Cost-effectiveness (CEA) and cost–utility analyses (CUA) have become popular types of economic evaluations (EE) used for evidence-based decision-making in healthcare resource allocation. Newborn screening programs (NBS) can have significant clinical benefits for society, and cost-effectiveness analysis may help to select the...
article 2020
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Verhoeckx, K. (author), lindholm Bøgh, K. (author), Constable, A. (author), Epstein, M.M. (author), hoffmann Sommergruber, K. (author), Holzhauser, T. (author), Houben, G. (author), Kuehn, A. (author), Roggen, E. (author), O'Mahony, L. (author), Remington, B. (author), Crevel, R. (author)
The growing world population and increased pressure on agricultural resources are driving a shortage of dietary protein sources. As a result, industry is developing more sustainable novel food protein sources such as insects, algae and duckweed and using new processing techniques. Consumer exposure to these novel or processed proteins, could...
article 2020
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Remington, B.C. (author), Blom, W.M. (author), Bassa, B. (author), Koppelman, S.J. (author)
Allergic reactions to meals consumed outside the home are common and can be severe and sometimes fatal. Objective. To quantify the risk reduction potentially achieved by increasing an individual’s threshold sensitivity to peanut (such as by means of immunotherapy) in scenarios of peanut exposure through shared kitchen materials in a restaurant...
article 2020
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Vasenev, A. (author), Hendriks, T. (author)
At the pre-concept stage, an architect explores the problem space together with various stakeholders, including engineers, marketing, and future users of the system. This requires competencies and tactics to communicate efficiently while maintaining a system-level scope. We present a practical Structured Problem Exploration approach to assist...
conference paper 2019
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Sutmuller, A.D. (author), den Hengst, M. (author), Barros, A.I. (author), van Gelder, P.H.A.J.M. (author)
This paper provides a comparison between four methodologies that assist criminal investigators in homicide investigations. The Person of Interest Priority Assessment Tool, Trace Investigate and Evaluate, Rasterfahndung, and Analysis of Competing Hypotheses are compared on their performance in the collection, prioritization, and elimination phase...
article 2018
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Jonkers, E. (author), Nellthorp, J. (author), Wilmink, I.R. (author), Olstam, J. (author)
In recent years, various field operational tests (FOTs) have been carried out in the EU to measure the real-world impacts of Intelligent Transport Systems (ITS). A challenge arising from these FOTs is to scale up from the very localised effects measured in the tests to a much wider set of socio-economic impacts, for the purposes of policy...
article 2018
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Leemans, M. (author), van der Aalst, W.M.P. (author), van den Brand, M.G.J. (author), Schiffelers, R.R.H. (author), Lensink, L. (author)
Over the last decades, the complexity of high-tech systems, and the softwaresystems controlling them,has increased considerably. In practice, it is hard to keep knowledge and documentation of these ever-evolving software systems up-to-date with their actual realization; we are dealing with legacy software. Clearly, this lack of knowledge,...
article 2018
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Steckling, N. (author), Gotti, A. (author), Bose-O'Reilly, S. (author), Chapizanis, D. (author), Costopoulou, D. (author), de Vocht, F. (author), Garí, M. (author), Grimalt, J.O. (author), Heath, E. (author), Hiscock, R. (author), Jagodic, M. (author), Karakitsios, S.P. (author), Kedikoglou, K. (author), Kosjek, T. (author), Leondiadis, L. (author), Maggos, T. (author), Mazej, D. (author), Polańska, K. (author), Povey, A. (author), Rovira, J. (author), Schoierer, J. (author), Schuhmacher, M. (author), Špirić, Z. (author), Stajnko, A. (author), Stierum, R. (author), Tratnik, J.S. (author), Vassiliadou, I. (author), Annesi-Maesano, I. (author), Horvat, M. (author), Sarigiannis, D.A. (author)
Background: The European Union's 7th Framework Programme (EU's FP7) project HEALS – Health and Environment-wide Associations based on Large Population Surveys – aims a refinement of the methodology to elucidate the human exposome. Human biomonitoring (HBM) provides a valuable tool for understanding the magnitude of human exposure from all...
article 2018
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Remington, B. (author), Broekman, H.C.H. (author), Blom, W.M. (author), Capt, A. (author), Crevel, R.W.R. (author), Dimitrov, I. (author), Faeste, C.K. (author), Fernandez-Canton, R. (author), Giavi, S. (author), Houben, G.F. (author), Glenn, K.C. (author), Madsen, C.B. (author), Kruizinga, A.K. (author), Constable, A. (author)
The development and introduction of new dietary protein sources has the potential to improve food supply sustainability. Understanding the potential allergenicity of these new or modified proteins is crucial to ensure protection of public health. Exposure to new proteins may result in de novo sensitization, with or without clinical allergy, or...
article 2018
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Malone, K. (author), Silla, A. (author), Johanssen, C. (author), Bell, D. (author)
Introduction: This paper describes the modification and development of methodologies to assess the impacts of Intelligent Transport Systems (ITS) applications for Vulnerable Road users (VRUs) in the domains of safety, mobility and comfort. This effort was carried out in the context of the VRUITS project whose aim was to produce results at the EU...
article 2017
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van Dommelen, P. (author), Schuller, A.A. (author)
Objectives. Untreated dental caries is the most prevalent medical condition worldwide, with considerable variations in prevalence between regions and countries. The care index (CI) and the restorative index (RI) are generally used to make comparisons between and within countries of levels of care delivered. However, several methodological...
article 2016
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Drupsteen, L. (author), Wybo, J.L. (author)
Most organisations aim to use experience from the past to improve safety, for instance through learning from safety-related incidents and accidents. Whether an organisation is able to learn successfully can however only be determined afterwards. So far, there are no proactive measures to assess whether an organisation will be able to learn from...
article 2015
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Barros, A.I. (author), Bijsterbosch, G. (author), van Mourik, M.R. (author), Noordkamp, H.W. (author), van der Vecht, B. (author)
Het aantal vermissingen is de laatste jaren steeds toegenomen, volgens Landelijk Bureau Vermiste Personen (De Telegraaf 2014), en het hoge aantal vereist een grote politie-inspanning. Het efficiënt en effectief aanpakken van een vermissing wordt dus alleen maar belangrijker. Dit artikel gaat in op de huidige werkwijze en problematiek bij...
article 2015
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Schelvis, R.M (author), Oude Hengel, K.M. (author), Burdorf, A. (author), Blatter, B.M. (author), Strijk, J.E. (author), van Beek, A.J. (author)
Occupational health researchers regularly conduct evaluative intervention research for which a randomized controlled trial (RCT) may not be the most appropriate design (eg, effects of policy measures, organizational interventions on work schedules). This article demonstrates the appropriateness of alternative designs for the evaluation of...
article 2015
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Klaver, M.H.A. (author), van Buul, K. (author), Nieuwenhuijs, A.H. (author), Luiijf, H.A.M. (author)
PREDICT has the objective to provide a comprehensive solution for dealing with cascading effects in multi-sectorial crisis situations covering aspects of critical infrastructures (CI). The PREDICT solution will be composed of the following three pillars: methodologies, models, and software tools. Their integrated use will increase the awareness...
report 2014
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Dessers, E. (author), Vrijhoef, H.J.M. (author), van Hootegem, G. (author), Dhondt, S. (author), Mutsaerts, A. (author), Pless, S. (author), van der Oord, S. (author), van der Klauw, D. (author), Vanermen, E. (author), Verhaeghe, N. (author), Vertriest, S. (author)
Conference abstract of the World Congress on Integrated Care 2, Sydney, 23-25 November 2014.
article 2014
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de Boer, J. (author), Steen, M.G.D. (author), Posthumus, A.L. (author)
Base-of-the-Pyramid (BoP) inclusive innovation projects aim to design, produce and market products and services for large and relatively poor market segments in developing countries, for example for people who have less than several dollars to spend per day. BoP projects have ‘normal’ goals, deliverables, budgets and timelines. In addition,...
conference paper 2013
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Jonkers, E. (author), Klunder, G. (author), Mahmod, M. (author), Benz, T. (author)
Applications of Information and Communication Technologies (ICT) have been identified to have a significant contribution to reduce energy consumption and CO2 emissions in the field of transport. The mechanisms by which ICT have an impact on CO2 emissions can be very complex, and calculating this impact requires various models (e.g. traffic and...
conference paper 2013
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