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Kluft, C. (author), Vellenga, E. (author), Brommer, E.J.P. (author), Wijngaards, G. (author), Gaubius instituut TNO (author)
This study concerns a case of congenital homozygous deficiency in ??2-antiplasmin associated with a severe hemorrhagic diathesis. Heterozygous family members also show a mild bleeding tendency. The propositus is a 17-yr-old male born of white parents and showing a severe hemorrhagic diathesis characterized by spontaneous bleeding in the joints...
article 1982
document
Vaandrager, G.J. (author), Bruining, G.J. (author), Veenhof, F.J. (author), Drayer, N.M. (author), TNO Preventie en Gezondheid (author)
The incidence of childhood diabetes (0-19 years of age) in The Netherlands, where there is no nationalized health-care system, was investigated retrospectively in the years 1978 to 1980 inclusive. The method chosen was a questionnaire among all Dutch paediatricians and internal physicians acting as consultants. Ascertainment was by the same...
article 1984
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Vaandrager, G.J. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
Chemicals/CAS: Autoantibodies; islet cell antibody; Mumps Vaccine
article 1986
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Hirasing, R.A. (author), Reerink, J.D. (author), de Vrind, S. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author)
article 1991
document
Kalsbeek, H. (author), Verrips, E. (author), Dirks, O.B. (author), TNO Preventie en Gezondheid (author)
A study was executed to investigate the relation between the use of fluoride tablets by children in the age period 1.5-6 yr on the one hand and the caries experience at the age of 6 and 15 yr and the prevalence of fluorosis at the age of 15 yr on the other hand. The year of birth of the child, the motivation of the mother to engage in preventive...
article 1992
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Meijer, W.J. (author), Verloove-Vanhorick, S.P. (author), Brand, R. (author), van den Brande, J.L. (author), TNO Preventie en Gezondheid (author)
In 563 surviving very preterm (<32 weeks gestational age) and/or very low birthweight (<1500 g) infants the relationship between neonatal thyroxine concentration and psychomotor development at 2 years of age (corrected for preterm birth) was studied. A significant association was found between low neonatal thyroxine concentration and a negative...
article 1992
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Hirasing, R.A. (author), Schaapveld, K. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
article 1993
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Reerink, J.D. (author), Herngreen, W.P. (author), Peters, A.C.B. (author), den Ouden, A.L. (author), Verloove-Vanhorick, S.P. (author), Ruys, J.H. (author), TNO Preventie en Gezondheid (author)
Objective. Assessment of the prevalence of convulsion-like symptoms in 1854 children of Dutch-speaking mothers of a population-based birth cohort. Method. At each child health clinic (CHC) visit mothers were asked whether they had noted any of the following signs: loss of consciousness, involuntary movements, eye rotation movements and apnoea,...
article 1994
document
Hirasing, R.A. (author), Verloove-Vanhorick, S.P. (author), van Kampen, L.T.B. (author), TNO Preventie en Gezondheid (author)
Objective. To assess the possibility of preventing consequences of bicycle accidents. Design. Retrospective study. Setting. The Netherlands. Material and method. The data on mortality and hospital admissions of children aged 0-14 years were analysed. The data on traffic accident fatalities were obtained from the Traffic Accidents Registration ...
article 1994
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Ruwaard, D. (author), Hirasing, R.A. (author), Reeser, H.M. (author), van Buuren, S. (author), Barker, K. (author), Heine, R.J. (author), Geerdink, R.A. (author), Bruining, G.J. (author), Vaandrager, G.J. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author)
OBJECTIVE - A nationwide retrospective study was conducted to assess the incidence of type 1 diabetes in The Netherlands among children <20 years of age in 1988-1990. The first study with a similar design covered 1978-1980. RESEARCH DESIGN AND METHODS - The capture-recapture census method was chosen for analysis of the data. A questionnaire was...
article 1994
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van de Kar, N.C.A.J. (author), van Hinsbergh, V.W.M. (author), Brommer, E.J.P. (author), Monnens, L.A.H. (author), Gaubius Laboratory TNO Preventie en Gezondheid Instituut voor verouderings- en vaatziekten onderzoek TNO (author)
Fibrinolytic parameters and von Willebrand factor (vWF) antigen were measured in the plasma of 10 patients with hemolytic uremic syndrome (HUS). Samples were taken at presentation and again 2 wk later, before and after infusion of 1-desamino-8-arginine vasopressin. Compared with the plasma values of healthy control children, levels of tissue...
article 1994
document
Verkerk, P.H. (author), TNO Preventie en Gezondheid (author)
Objective. Evaluation of the Dutch national screening programme for phenylketonuria (PKU). Design. Descriptive. Setting. Nationwide. Methods. Data on the screening were obtained from the laboratories, from the registration offices of vaccination and screening results and from the paediatricians to whom infants with positive screening values were...
article 1995
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Brussaard, J.H. (author), Hulshof, K.F.A.M. (author), Löwik, M.R.H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
To estimate the effect of possible goitre prophylactic measures on the intake of iodine among population groups, simulation studies, based on the first Dutch National Food Consumption Survey, were carried out. Iodine intake figures and prevalence of low intakes were calculated after fictively iodizing either bread, a combination of industrial...
article 1995
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Meulenbelt, I. (author), Droog, S. (author), Trommelen, G.J.M. (author), Boomsma, D.I. (author), Slagboom, P.E. (author), TNO Preventie en Gezondheid (author)
article 1995
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Hirasing, R.A. (author), TNO Preventie en Gezondheid (author)
Objective: To determine if the incidence of insulin-dependent diabetes mellitus (IDDM) in the age group of 0-19 years in the Netherlands in the period 1988-1990 had changed in comparison with the period 10 years before. Design: Retrospective. Setting: The Netherlands. Method: In 1991 a questionnaire was sent to all paediatricians and internists...
article 1995
document
Cornelissen, E.A.M. (author), Hirasing, R.A. (author), Monnens, L.A.H. (author), TNO Preventie en Gezondheid (author)
Objective. To determine the prevalence of vitamin K deficiency bleeding in the Netherlands, in order to evaluate the efficacy of recommendations on vitamin K prophylaxis. Design. Descriptive. Setting. University Hospital Nijmegen, the Netherlands. Methods. Active surveillance of vitamin K deficiency bleeding (VKDB) by the Dutch Paediatric...
article 1996
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Ruwaard, D. (author), Gijsen, R. (author), Bartelds, A.I.M. (author), Hirasing, R.A. (author), Verkleij, H. (author), Kromhout, D. (author), TNO Preventie en Gezondheid (author)
OBJECTIVE - To assess possible changes in the incidence of diabetes in all age-groups in The Netherlands during a 10-year period (1980-1983/1990-1992). RESEARCH DESIGN AND METHODS - Since 1970, a network of sentinel stations (the Dutch Sentinel Practice Network) consisting of ∼1% of the Dutch population has been in operation to gain insight into...
article 1996
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Brussaard, J.H. (author), van Dokkum, W. (author), van der Paauw, C.G. (author), de Vos, R.H. (author), de Kort, W.L.A.M. (author), Löwik, M.R.H. (author), TNO Voeding (author)
To assess the level of exposure to food contaminants (cadmium, lead, PCBs, DDT, hexachlorobenzene, nitrate and malathion) a total-diet study was carried out. A total of 226 food products were analysed individually; the concentration of contaminants in products not selected for analysis was estimated with the help of published data. The results...
article 1996
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Oostvogel, P.M. (author), van Conyn-Spaendonck, M.A.E. (author), Hirasing, R.A. (author), van Loon, A.M. (author), TNO Preventie en Gezondheid (author)
report 1996
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Schweitz, R. (author), Mopurgo, R. (author), Sietaram, M.A. (author), Hirasing, R.A. (author), TNO Preventie en Gezondheid (author)
Objective: To determine the extent and severity of malnutrition in children in the last 10 years in 's Lands Hospitaal. Setting: Paramaribo, Surinam. Design: Retrospective descriptive study. Method: Data were collected from the medical files of children admitted because of malnutrition, by completing a standard questionnaire. Results: The number...
article 1996
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