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Cornelissen, E.A.M. (author), Hirasing, R.A. (author), Monnens, L.A.H. (author), TNO Preventie en Gezondheid (author)
Objective. To determine the prevalence of vitamin K deficiency bleeding in the Netherlands, in order to evaluate the efficacy of recommendations on vitamin K prophylaxis. Design. Descriptive. Setting. University Hospital Nijmegen, the Netherlands. Methods. Active surveillance of vitamin K deficiency bleeding (VKDB) by the Dutch Paediatric...
article 1996
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Ruwaard, D. (author), Gijsen, R. (author), Bartelds, A.I.M. (author), Hirasing, R.A. (author), Verkleij, H. (author), Kromhout, D. (author), TNO Preventie en Gezondheid (author)
OBJECTIVE - To assess possible changes in the incidence of diabetes in all age-groups in The Netherlands during a 10-year period (1980-1983/1990-1992). RESEARCH DESIGN AND METHODS - Since 1970, a network of sentinel stations (the Dutch Sentinel Practice Network) consisting of ∼1% of the Dutch population has been in operation to gain insight into...
article 1996
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Reijneveld, S.A. (author), de Meer, G. (author), Wiefferink, C.H. (author), Crone, M.R. (author), TNO Kwaliteit van Leven (author)
article 2008
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Reerink, J.D. (author), Herngreen, W.P. (author), Peters, A.C.B. (author), den Ouden, A.L. (author), Verloove-Vanhorick, S.P. (author), Ruys, J.H. (author), TNO Preventie en Gezondheid (author)
Objective. Assessment of the prevalence of convulsion-like symptoms in 1854 children of Dutch-speaking mothers of a population-based birth cohort. Method. At each child health clinic (CHC) visit mothers were asked whether they had noted any of the following signs: loss of consciousness, involuntary movements, eye rotation movements and apnoea,...
article 1994
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Joustra, S.D. (author), van der Plas, E.M. (author), Goede, J. (author), Oostdijk, W. (author), Delemarre-van de Waal, H.A. (author), Hack, W.W.M. (author), van Buuren, S. (author), Wit, J.M. (author)
Aim Accurate calculations of testicular volume standard deviation (SD) scores are not currently available. We constructed LMS-smoothed age-reference charts for testicular volume in healthy boys. Methods The LMS method was used to calculate reference data, based on testicular volumes from ultrasonography and Prader orchidometer of 769 healthy...
article 2015
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Visser, O. (author), Busquet, E.H. (author), van Leeuwen, F.E. (author), Aaronson, N.K. (author), Öry, F.G. (author), TNO Preventie en Gezondheid (author)
Objective. To describe the incidence of cervical cancer in women in North-Holland by country of birth. Design. Descriptive epidemiological study based on data from cancer registries. Method. The number of cases of cervical cancer in North-Holland for the period 1988-1998 was determined using data from the regional cancer registry of the...
article 2003
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Kluft, C. (author), Vellenga, E. (author), Brommer, E.J.P. (author), Wijngaards, G. (author), Gaubius instituut TNO (author)
This study concerns a case of congenital homozygous deficiency in ??2-antiplasmin associated with a severe hemorrhagic diathesis. Heterozygous family members also show a mild bleeding tendency. The propositus is a 17-yr-old male born of white parents and showing a severe hemorrhagic diathesis characterized by spontaneous bleeding in the joints...
article 1982
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Brussaard, J.H. (author), van Dokkum, W. (author), van der Paauw, C.G. (author), de Vos, R.H. (author), de Kort, W.L.A.M. (author), Löwik, M.R.H. (author), TNO Voeding (author)
To assess the level of exposure to food contaminants (cadmium, lead, PCBs, DDT, hexachlorobenzene, nitrate and malathion) a total-diet study was carried out. A total of 226 food products were analysed individually; the concentration of contaminants in products not selected for analysis was estimated with the help of published data. The results...
article 1996
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Borghi, E. (author), de Onis, M. (author), Garza, C. (author), van den Broeck, J. (author), Frongillo, E.A. (author), Grummer-Strawn, L. (author), van Buuren, S. (author), Pan, H. (author), Molinari, L. (author), Martorell, R. (author), Onyango, A.W. (author), Martines, J.C. (author), Pinol, A. (author), Siyam, A. (author), Victoria, C.G. (author), Bhan, M.K. (author), Araújo, C.L. (author), Lartey, A. (author), Owusu, W.B. (author), Bhandari, N. (author), Norum, K.R. (author), Bjoerneboe, G.-E.Aa. (author), Mohamed, A.J. (author), Dewey, K.G. (author), Belbase, K. (author), Chumlea, C. (author), Cole, T. (author), Shrimpton, R. (author), Albernaz, E. (author), Tomasi, E. (author), de Cássia Fossati da Silveira, R. (author), Nader, G. (author), Sagoe-Moses, I. (author), Gomez, V. (author), Sagoe-Moses, C. (author), Taneja, S. (author), Rongsen, T. (author), Chetia, J. (author), Sharma, P. (author), Bahl, R. (author), Baerug, A. (author), Tufte, E. (author), Alasfoor, D. (author), Prakash, N.S. (author), Mabry, R.M. (author), Al Rajab, H.J. (author), Helmi, S.A. (author), Nommsen-Rivers, L.A. (author), Cohen, R.J. (author), Heinig, M.J. (author), TNO Kwaliteit van Leven (author)
The World Health Organization (WHO), in collaboration with a number of research institutions worldwide, is developing new child growth standards. As part of a broad consultative process for selecting the best statistical methods, WHO convened a group of statisticians and child growth experts to review available methods, develop a strategy for...
article 2006
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Verkerk, P.H. (author), TNO Preventie en Gezondheid (author)
Objective. Evaluation of the Dutch national screening programme for phenylketonuria (PKU). Design. Descriptive. Setting. Nationwide. Methods. Data on the screening were obtained from the laboratories, from the registration offices of vaccination and screening results and from the paediatricians to whom infants with positive screening values were...
article 1995
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Weijerman, M.E. (author), van Furth, A.M. (author), Vonk Noordegraaf, A. (author), van Wouwe, J.P. (author), Broers, C.J.M. (author), Gemke, R.J.B.J. (author), TNO Kwaliteit van Leven (author)
Objective: To determine the prevalence, neonatal characteristics, and first-year mortality in Down syndrome (DS) among children in the Netherlands. Study design: The number of DS births registered by the Dutch Paediatric Surveillance Unit (DPSU) in 2003 was compared with total live births (reference population) and perinatal registrations....
article 2008
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Bank, R.A. (author), Tekoppele, J.M. (author), Janus, G.J.M. (author), Wassen, M.H.M. (author), Pruijs, H.E.H. (author), van der Sluijs, H.A.H. (author), Sakkers, R.J.B. (author)
The brittleness of bone in patients with osteogenesis imperfecta (OI) has been attributed to an aberrant collagen network. However, the role of collagen in the loss of tissue integrity has not been well established. To gain an insight into the biochemistry and structure of the collagen network, the cross-links hydroxylysylpyridinoline (HP) and...
article 2000
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van Buuren, S. (author), Bonnemaijer-Kerckhoffs, D.J.A. (author), Grote, F.K. (author), Wit, J.M. (author), Verkerk, P.H. (author), TNO Preventie en Gezondheid (author)
The number of referrals under strict adherence to the Dutch consensus guidelines for short stature was estimated using longitudinal data from 970 children (0-10 years). Results showed that over 38% of all children would have to be referred one or more times. There is therefore a clear need to revise the current guidelines.
article 2004
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Hack, W.W.M. (author), Voort van der-Doedens, L.M. (author), Sijstermans, K. (author), Meijer, R.W. (author), Pierik, F.H. (author), TNO Kwaliteit van Leven (author)
Background: Since the mid-1990s, acquired undescended testis has gradually been recognised as a separate entity for which the efficacy of prepubertal surgery has not been univocally been demonstrated. Therefore, in our hospital, orchidopexy was no longer routinely performed for acquired undescended testis. Aim: To investigate the effect of...
article 2007
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van Buuren, S. (author), Bezemer, R.A. (author), Reijneveld, S.A. (author), L' Hoir, M.P. (author)
Curve matching is a new big data technique to predict an outcome given earlier measurements. Here we apply curve matching to predict the future growth of a specific child, the target child. The method searches in large datasets of longitudinal growth data for other children who are similar to the target child in terms of factors that influence...
article 2015
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Theunissen, N.C.M. (author), Tates, K. (author), TNO Technische Menskunde (author)
The aim of this review is to gain a comprehensive view on the theories and models referred to in studies on educating and counseling children about physical health. A computer search was conducted using PubMed Medline, and Silverplatter Webspirs Psycinfo. Original studies, reviews, and theoretical papers published between 1992-2003 were included...
article 2004
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van Buuren, S. (author), Fredriks, M. (author)
The worm plot visualizes differences between two distributions, conditional on the values of a covariate. Though the worm plot is a general diagnostic tool for the analysis of residuals, this paper focuses on an application in constructing growth reference curves, where the covariate of interest is age. The LMS model of Cole and Green is used to...
article 2001
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Vaandrager, G.J. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
Chemicals/CAS: Autoantibodies; islet cell antibody; Mumps Vaccine
article 1986
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Kalsbeek, H. (author), Verrips, E. (author), Dirks, O.B. (author), TNO Preventie en Gezondheid (author)
A study was executed to investigate the relation between the use of fluoride tablets by children in the age period 1.5-6 yr on the one hand and the caries experience at the age of 6 and 15 yr and the prevalence of fluorosis at the age of 15 yr on the other hand. The year of birth of the child, the motivation of the mother to engage in preventive...
article 1992
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Goldbohm, R.A. (author), Brants, H.A.M. (author), Hulshof, K.F.A.M. (author), van den Brandt, P.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
This study presents data on dietary intake of specific carotenoids in the Netherlands, based on a recently developed food composition database for carotenoids. Regularly eaten vegetables, the main dietary source of carotenoids, were sampled comprehensively and analysed with modern analytic methods. The database was complemented with data from...
article 1998
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