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van der Beek, E.J. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
The inter-relationship of food and physical performance, food is considered as a conglomerate of nutrients and man is depicted as a kind of organic pudding. This 'machine' concept of human performance in combination with the mysticism surrounding vitamins, has led to the faddish belief that additional vitamins are necessary to improve physical...
article 1985
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Speek, A.J. (author), Thissen, J.T.N.M. (author), Schrijver, J. (author), Instituut CIVO-Toxicologie en voeding TNO (author)
The urinary excretion of 3-methylhistidine and creatinine and the urinary 3-methylhistidine to creatinine excretion ratio during day and night were investigated in a group of 103 healthy, normally fed Dutch children (52 boys and 51 girls) aged 2-17 years. The 3-methylhistidine to creatinine ratio of the night urine appeared to be significantly...
article 1986
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Brommer, E.J.P. (author), Derkx, F.H.M. (author), Schalekamp, M.A.D.H. (author), Dooijewaard, G. (author), Klaauw, V.D.M.M. (author), Gaubius instituut TNO (author)
In eight male patients with normal liver and kidney function fibrinolytic components were measured in arterial blood and in renal and hepatic vein blood, obtained during catheterization for analysis of hypertension. Blood samples were collected simultaneously from veins und corresponding arteries before and 5 minutes after the completion of...
article 1988
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van Poppel, G. (author), Schrijver, J. (author), Meulmeester, J.F. (author), Kempen-Voogd, N. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Chemicals/CAS: Cholesterol, 57-88-5; Iron, 7439-89-6; Vitamins
article 1989
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Emeis, J.J. (author), van Houwelingen, A.C. (author), van den Hoogen, C.M. (author), Hornstra, G. (author), Gaubius Institute TNO, 2300 AP Leiden, Netherlands (author)
For a period of 6 weeks, 76 healthy male volunteers consumed during their daily main meal the contents of one tin (~ 135 g) of either fish (mackerel) paste or meat paste. Fibrinolytic parameters were determined in plasma samples obtained at the beginning and at the end of the experimental period. No changes were found in plasminogen, α2...
article 1989
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Daanen, H.A.M. (author), van de Linde, F.J.G. (author)
Four noninvasive rewarming techniques for mildly hypothermic subjects were compared. Seven subjects were cooled in a water bath of 15°C for 2 h to an average esophageal temperature (Tes) of 36°C. Thereafter, the subjects were rewarmed by immersion of the body in a water bath of 42°C (Method 1), the body but not the extremities in water of 42°C ...
article 1992
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Korteling, J.E. (author)
When a dual-tracking task, consisting of two incoherent (uncorrelated) subtasks is partly integrated, such that it is characterized by incompatibility of similarity, or when axis similarity of subtasks is high, it may be difficult to map subtask stimuli to the proper responses. Especially for older adults, an increase in mapping demands may be a...
article 1993
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Zwart, A. (author), TNO Voeding Instituut CIVO-Toxicologie en Voeding TNO (author)
The effect of flow and flow patterns on the resistance of the airways was reinvestigated. A new way to describe pressure-flow relationships is introduced. Normalized resistance, Rn, is defined as resistance (P/φ) divided by the viscosity of the inspired gas (μ) relative to air (Rn = Rμ(u)/μ). Normalized flow φn is defined as flow times relative...
article 1994
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Vink, P. (author), Douwes, M. (author), van Woensel, W. (author)
The effects of a portable back support, the Back-Up, were tested in 28 variables. Both subjective and objective physical load measures were recorded during sitting with and without Back-Up, most of them during VDU work. The main result was that the posture of the upper back and neck/head was improved by the Back-Up. However, the knee straps...
article 1994
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Hildebrandt, V.H. (author), TNO Preventie en Gezondheid (author)
A postal questionnaire survey was carried out in Dutch agriculture to identify high risk branches with respect to musculoskeletal symptoms and workload. The study population comprised a sample 2580 male employees and employers, with a response rate of 49%. A total of 75% of the employees and 71% of the employers reported musculoskeletal symptoms...
article 1995
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Hildebrandt, V.H. (author), Bongers, P.M. (author), Dul, J. (author), van Dijk, F.J.H. (author), Kemper, H.C.G. (author), TNO Preventie en Gezondheid (author)
To determine priorities for ergonomic improvements in five maintenance departments of a steel company, a study was carried out to identify groups with a high prevalence of musculoskeletal problems or a high exposure to unfavourable musculoskeletal workload. All workers were asked to complete a standardized questionnaire on musculoskeletal...
article 1996
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Andries, F. (author), Kompier, M.A.J. (author), Smulders, P.G.W. (author), TNO Preventie en Gezondheid (author)
A secondary analysis was performed on a large scale cross-sectional survey (n = 12,500) by the European Foundation for the Improvement of Living and Working Conditions. The analysis investigates (1) 'strain', i.e. whether or not employees in 12 European Union (EU) member states considered their health or safety to be at risk because of their...
article 1996
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Dahl, M.L. (author), Voortman, G. (author), Alm, C. (author), Elwin, C.E. (author), Delbressine, L. (author), Vos, R. (author), Bogaards, J.J.P. (author), Bertilsson, L. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
The novel antidepressant mirtazapine is a racemate with both noradrenergic and serotonergic potentiating effects. In vitro metabolism of racemic mirtazapine was studied in (a) microsomes from cells expressing different cytochrome P450 (CYP) enzymes and (b) human liver microsomes from 10 subjects and compared with the rate of metabolism of 4...
article 1997
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Srikumar, T.S. (author), Wezendonk, B. (author), van Dokkum, W. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In the present pilot study, for investigating the physiological effects of different types of nondigestible oligosaccharides, we have validated the application of methodologies for the analysis of bile acids and neutral steroids in feces of human subjects. The accuracy of the extraction and chromatographic procedures for the analyses of bile...
article 1998
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Löwik, M.R.H. (author), Hulshof, K.F.A.M. (author), van der Heijden, L.J.M. (author), Brussaard, J.H. (author), Burema, J. (author), Kistemaker, C. (author), de Vries, P.J.F. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
From April 1987-March 1988, the first Dutch National Food Consumption Survey (DNFCS) was carried out among 2203 households comprising 5898 subjects, aged 1-85. In 1992 (January-December) the second DNFCS was conducted among 6218 subjects, aged 1-92 belonging to 2475 households. In both surveys, among other things, information on individual food...
article 1998
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Schaafsma, G. (author), Meuling, W.J.A. (author), van Dokkum, W. (author), Bouley, C. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To investigate in adult male volunteers the effect of a new fermented milk product, fermented by Lactobacillus acidophilus and with fructo-oligosaccharides added, on blood lipids. Design: Randomized placebo-controlled double-blind two-way cross over trial with two treatment periods of three weeks, separated by a wash-out period of one...
article 1998
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Mannaerts, B.M.J.L. (author), Geurts, T.B.P. (author), Odink, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The objective of this study was to compare the bioavailability of s.c. and i.m. administration of human chorionic gonadotrophin (HCG; Pregnyl®). In a randomized, single centre, three-way cross-over study, 18 healthy pituitary-suppressed volunteers were assigned to single HCG injections of 5000 and 10000 IU i.m. and 10000 IU s.c. Rate (C(max), t...
article 1998
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Centraal Instituut voor Voedingsonderzoek TNO (author), Oostenbrug, G.S. (author), Mensink, R.P. (author), Al, M.D.M. (author), van Houwelingen, A.C. (author), Hornstra, G. (author)
During pregnancy, maternal plasma concentrations of the peroxidation-susceptible polyunsaturated fatty acids (polyenes) increase. In addition, the proportion of polyenes is higher in neonatal plasma than in maternal plasma. To study whether these increased amounts of polyenes affect antioxidant levels, we measured lipid-soluble antioxidants in...
article 1998
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van Dokkum, W. (author), Wezendonk, B. (author), Srikumar, T.S. (author), van den Heuvel, E.G.H.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To study the effect of the intake of 15 g nondigestible oligosaccharides per day on various parameters of large-bowel function, as well as on blood lipid concentrations and glucose absorption in man. Design: Latin square, randomized, double-blind, diet-controlled. Setting: Metabolic research unit. Subjects: Twelve apparently healthy...
article 1999
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van de Vijver, L.P.L. (author), Kardinaal, A.F.M. (author), Charzewska, J. (author), Rotily, M. (author), Charles, P. (author), Maggiolini, M. (author), Ando, S. (author), Väänänen, K. (author), Wajszczyk, B. (author), Heikkinen, J. (author), Deloraine, A. (author), Schaafsma, G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Several studies indicate that intake of calcium can inhibit iron absorption especially when taken simultaneously. In the CALEUR study, a cross-sectional study among girls (mean 13.5 y) and young women (mean 22.0 y) in six European countries, the association between calcium intake and iron status was studied. In 1,080 girls and 524 women,...
article 1999
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