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van der Giessen, A.M. (author), Gijsbers, G.W. (author), Koops, R. (author), van der Zee, F.A. (author)In opdracht van de Commissie Genetische Modificatie (COGEM) heeft TNO een deskstudie uitgevoerd getiteld “Economische analyse van de Nederlandse biotechnologiesector”. Deze analyse is één van de voorstudies die de COGEM laat uitvoeren als voorbereiding op de Trendanalyse Biotechnologie, die naar verwachting in 2015 zal worden uitgevoerd. Voor...report 2014
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- van Ommen, B. (author) public lecture 2017
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- Langelaan, M.L.P. (author), Kock, L.M. (author), Petit, A. (author), van Ee, R. (author), Timmer, K. (author), Ito, K. (author), Papen-Botterhuis, N.E. (author) public lecture 2011
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- Wieringa, F.P. (author), TNO Industrie en Techniek (author) public lecture 2009
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Abeln, E. (author), Posno, M. (author), Nishide, K. (author)TNO recently developed InTESTine™ in order to study the absorption and translocation of pharmaceutical, biological and nutritional compounds across the intestinal wall in a physiologically relevant model. This system uses fresh ex vivo intestinal tissue mounted into a two compartment model. So far, this has been the missing link in our toolbox...other 2013
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Abeln, E. (author)TNO combines state of the art technologies, such as organoids, high throughput sequencing and computational modelling to gain insight and discover functionalities in complex biological systems, to unlock our microbiome for your applications. Our microbiome analysis and modelling techniques can help in solving questions, such as: How does this...other 2014
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Erpelinck, E. (author)TNO’s intestinal screening model (TNO i-screen) helps to quickly identify pharmacological compounds that are metabolized by intestinal microbiota. For pharmaceutical companies, searching for novel pharmaceuticals is a complex and time-consuming process. When a novel drug has been selected, extensive in vitro and clinical studies are required to...other 2016
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Abeln, E. (author), Posno, M. (author)TNO’s intestinal screening model (TNO i-screen) helps to quickly identify food ingredients that modulate the intestinal microbiota composition. For manufacturers, searching for health-promoting ingredients is a complex and time-consuming process. Large numbers of substances have to be screened, while for some components almost no proper...other 2016
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Vaes, W. (author), Meijer, T. (author)The development of new medicines is a costly and timeconsuming process. As a result, companies are always locking for ways to increase the efficiency of their pipeline. One way to do that is by using microtracer dosing. Microtracing is an innovative technology in which very small quantities of substances are tested in humans at very early stage...other 2017
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- Fentener van Vlissingen, M. (author), Grootaers, G. (author), Groothuis, G. (author), van Hilten, J.A. (author), Krul, C.A.M. (author), van Veen, E.B. (author), van de Waart, B. (author) other 2017
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Abeln, E. (author)TNO is searching for partners for a consortium research project aiming at the identification of novel solutions for controlling pathogenic Clostridia such as Clostridium difficile and C. perfringens. These are a serious threat for human and animal health and a major reason for using antibiotics. Novel solutions preventing disease development...other 2017
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Abeln, E. (author)For the industry, knowledge of microbial viability is the key to increased production eficacy, treatment procedure selection, process optimization, and high product quality. TNO has developed a user-friendly fuorescence based test for microbial live-dead assessment. This rapid and cost-eficient method was successfully tested with a diverse range...other 2018
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- Prinsen, M.K. (author) doctoral thesis 2014
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- Medisch Biologisch Laboratorium TNO (author), Jansz, H.S. (author) doctoral thesis 1957
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- Arts, C.J.M. (author) doctoral thesis 1992
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- TNO Kwaliteit van Leven (author), Bode, W. (author) doctoral thesis 1992
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- TNO Voeding (author), van der Kop, D.A.M. (author) doctoral thesis 1995
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- TNO Voeding (author), Sloot, W.N. (author) doctoral thesis 1995
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- TNO Voeding Centrum voor fytotechnologie (author), Heimovaara-Dijkstra, S. (author) doctoral thesis 1995
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- Medisch Biologisch Laboratorium TNO (author), Plooy, C.A.M. (author) doctoral thesis 1984