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Schlunk, F. (author), Fisher, P. (author), Princen, H.M.G. (author), Rex, A. (author), Prinz, V. (author), Foddis, M. (author), Lütjohann, D. (author), Laufs, U. (author), Endres, M. (author)
Monoclonal anti-proprotein convertase subtilisin/kexin type 9 (PSCK9) neutralizing antibodies effectively lower plasma cholesterol levels and decrease cardiovascular events but also raised some concern that cognitive function could worsen as a side effect. Here, we performed experiments in mice to characterize the effect of anti-PCSK9 antibodies...
article 2021
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Ligthart, M.E.U. (author), Neerincx, M.A. (author), Hindriks, K.V. (author)
While interacting with a social robot, children have a need to express themselves and have their expressions acknowledged by the robot. A need that is often unaddressed by the robot, due to its limitations in understanding the expressions of children. To keep the child-robot interaction manageable the robot takes control, undermining children's...
conference paper 2021
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van Zoelen, E.M. (author), van den Bosch, K. (author), Neerincx, M.A. (author)
A team develops competency by progressive mutual adaptation and learning, a process we call co-learning. In human teams, partners naturally adapt to each other and learn while collaborating. This is not self-evident in human-robot teams. There is a need for methods and models for describing and enabling co-learning in human-robot partnerships....
conference paper 2021
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van Gulijk, C. (author)
Ook preventiemedewerkers hebben een belangrijke rol in deze coronatijd. In dit artikel uit de frontlinie vertelt Pieter Diehl over de coördinerende taken van de preventiemedewerkers en hun communicatie met de afdeling HR.
article 2021
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Rijnders, M. (author), Jans, S (author), Groesen, K. (author)
Reduced antenatal care services and an acute halt to Centeringbased antenatal group care were one of the results of the COVID-19 lockdown in the Netherlands. The pandemic and the subsequent reduction in antenatal services gave rise to anxiety and stress in pregnant women, increasing the need for group antenatal care more than ever. Throughout...
article 2021
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van Gulijk, C. (author)
In deze coronatijd blijkt steeds meer dat arbodeskundigen een sleutelrol vervullen. Dit keer vertelt veiligheidskundige Richard van Sonsbeek over zijn ervaringen bij inspectiebedrijf Saybolt. Met een koel hoofd beheerst hij de coronacrisis. Wederom een verhaal door Coen van Gulijk uit de frontlinie.
article 2021
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van Gulijk, C. (author)
Arboprofessionals hebben een belangrijke rol in deze coronatijd. In dit artikel uit de frontlinie vertelt arbeidshygiënist Tamara Onos aan Coen van Gulijk over het deskundigenteam waarin zij werkt. "Samenwerken en afstemmen zijn kernwaarden en die hebben we gebruikt in het protocol."
article 2021
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Ots, P. (author), van Zon, S. (author), Schram, J. (author), Burdorf, A. (author), Robroek, S. (author), Oude Hengel, K. (author), Brouwer, S. (author)
Steeds meer werkenden krijgen te maken met een chronische ziekte tijdens hun loopbaan. Op dit moment heeft ongeveer 30% van de werkenden in Europa een chronische ziekte.1 Werkenden met een chronische ziekte hebben vaker een lager werkvermogen, een verminderde arbeidsproductiviteit en ze hebben een verhoogd risico om vroegtijdig de arbeidsmarkt...
article 2021
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van Gulijk, C. (author), Zaitseva, E. (author)
Computational intelligence is rapidly becoming an essential part of reliability engineering. This book offers a wide spectrum of viewpoints on the merger of technologies. Leading scientists share their insights and progress on reliability engineering techniques, suitable mathematical methods, and practical applications. Thought-provoking ideas...
book 2021
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Duijster, D. (author), Vermaire, E.J.H. (author)
bookPart 2021
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van Gulijk, C. (author)
This work puts Computational Intelligence in Reliability Engineering in perspective within the larger framework of digitalization and business. The approach is to consider RECI solutions as business solutions in a wider enterprise architecture environment. Using that as a starting point four key components are discussed for successful...
bookPart 2021
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Goemans, B.F. (author), Noort, S. (author), Blink, M. (author), Wang, Y.D. (author), Peters, S.T.C.J. (author), van Wouwe, J.P. (author), Kaspers, G. (author), de Haas, V. (author), Kollen, W.J. (author), van der Velden, V.H.J. (author), Gruber, T.A. (author), Zwaan, C.M. (author)
The aim of this study was to define a population-based frequency of TAM in DS newborns. The Dutch Pediatric Surveillance Unit (DPSU) registers newborns with DS and TAM screening was added to this registration from Jan 1, 2008, until Jan 1, 2013 (Erasmus MC MEC-2007-168, Netherlands Trial Register NL1587). Based on the live birth prevalence of DS...
article 2021
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Vermaire, J.H. (author), Kalf, S.M. (author), Schuller, A.A. (author)
Background. People with intellectual disabilities have worse health outcomes compared to their peers without. However, regarding oral health parameters, recent systematic reviews reported conflicting evidence. The aim was to assess whether adolescents with MBID differ from their peers in oral health and oral health behaviour. Methods. Ninety...
article 2021
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Gopaul, V.S. (author), Pieterman, E.J. (author), Princen, H.M.G. (author), Bergenholm, L. (author), Lundborg, E. (author), Cavallin, A. (author), Johansson, M.J. (author), Hawthorne, G. (author), Björkbom, A. (author), Hammarberg, M. (author), Li, X. (author), Jarke, A. (author), Bright, J. (author), Svensson, L. (author), Jansson-Löfmark, R. (author), Abrahamsson, B. (author), Agrawal, R. (author), Hurt-Camejo, E. (author)
We investigated the effects of mineral oil on statin pharmacokinetics and inflammatory markers in animal models. A new synthesis strategy produced regioisomers that facilitated the characterization of the main metabolite (M1) of atorvastatin, a lipophilic statin, in C57BL/6NCrl mice. The chemical structure of M1 in mice was confirmed as ortho...
article 2021
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Blonk, R. (author)
In alles heb je rekkelijken en preciezen. Zo ook in het verstrekken en controleren van toeslagen en uitkeringen. Nu na jaren de gevolgen van de dominantie van de preciezen voelbaar zijn, lijkt de slinger weer wat meer de andere kant op te bewegen. De menselijke maat als term is terug in het debat en iedereen heeft het over een andere vorm van...
article 2021
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van Gemert, Y. (author), Kozijn, A.E. (author), Pouwer, M.G. (author), Kruisbergen, N.N.L. (author), van den Bosch, M.H.J. (author), Blom, A.B. (author), Pieterman, E.J. (author), Weinans, H. (author), Stoop, R. (author), Princen, H.M.G. (author), van Lent, P.L.E.M. (author)
Objective: High systemic cholesterol levels have been associated with osteoarthritis (OA) development. Therefore, cholesterol lowering by statins has been suggested as a potential treatment for OA. We investigated whether therapeutic high-intensive cholesterol-lowering attenuated OA development in dyslipidemic APOE*3Leiden.CETP mice. Methods:...
article 2021
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Burdorf, A. (author), Pronk, A. (author), Peters, S. (author), Oude Hengel, K. (author), Stokholm, Z. (author), Kolstad, H. (author), Schlunssen, V. (author), van Veldhoven, K. (author), Basinas, I. (author), van Tongeren, M. (author)
public lecture 2021
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Houtman, I.L.D. (author), Vanroelen, C. (author), Kraan, K.O. (author)
The majority of people living with a common mental disorder are employed, but many are at greater risk of job loss and permanent labor market exclusion than colleagues without these problems (OECD; Organization for Economic Cooperation and Development, 2012). In addition, the costs of mental ill-health for society are large, reaching 3;4.5% of...
bookPart 2021
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Gijsbertse, K. (author), Linssen, L. (author), Woering, A. (author), Catoire, M. (author)
Background. Soldiers are required to conduct tasks and operations in physically demanding situations, where the ability to move (mobility) quickly is important to lethality and survivability. This study employed a specially designed suit to try to isolate the main mass property characteristics of personal protective clothing/equipment (PPCE)...
article 2021
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Kermavnar, T. (author), de Vries, A.W. (author), de Looze, M.P. (author), O'Sullivan, L.W. (author)
This study is an updated systematic review of papers published in the last 5 years on industrial back-support exoskeletons. The research questions were aimed at addressing the recent findings regarding objective (e.g. body loading, user performance) and subjective evaluations (e.g. user satisfaction), potential side effects, and methodological...
article 2021
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