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Fransman, W. (author), Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author)Objectives: Within the chemical legislation, REACH was implemented in order to improve safe working conditions with hazardous substances. Literature and real-life experiences by those concerned have shown that there are still gaps with a need for improved risk communication. This study elaborated on how information provided by REACH is...article 2023
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Vreeken, D. (author), Seidel, F. (author), de La Roij, G. (author), Vening, W. (author), den Hengst, W.A. (author), Verschuren, L. (author), Özsezen, S. (author), Kessels, R.P.C. (author), Duering, M. (author), Mutsaerts, H.J.M.M. (author), Kleemann, R. (author), Wiesmann, M. (author), Hazebroek, E.J. (author), Kiliaan, A.J. (author)BACKGROUND AND OBJECTIVE: While underlying pathophysiology linking obesity to brain health is not completely understood, white adipose tissue (WAT) is considered a key player. In obesity, WAT becomes dysregulated, showing hyperplasia, hypertrophy, and eventually inflammation. This disbalance leads to dysregulated secretion of adipokines...article 2023
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Vreeken, D. (author), Seidel, F. (author), Custers, E.M. (author), Olsthoorn, L. (author), Cools, S. (author), Aarts, E.O. (author), Kleemann, R. (author), Kessels, R. (author), Weismann, M. (author), Hazebroek, E.J. (author), Killiaan, A.J. (author)Importance: Bariatric surgery-induced weight loss is often associated with improved cognitive function. However, improvement in cognitive function is not always exhibited by all patients, and the mechanisms behind cognitive improvement remain unknown. Objective: To investigate the association of changes in adipokines, inflammatory factors, mood,...article 2023
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Blaauwendraad, S.M. (author), Stevens, D.R. (author), van den Dries, M.A. (author), Gaillard, R. (author), Pronk, A. (author), Spaan, S. (author), Ferguson, K.K. (author), Jaddoe, V.W.V. (author)BACKGROUND: Fetal exposure to organophosphate (OP) pesticides might lead to fetal metabolic adaptations, predisposing individuals to adverse metabolic profiles in later life. OBJECTIVE: We examined the association of maternal urinary OP pesticide metabolite concentrations in pregnancy with offspring body mass index (BMI) and fat measures at 10...article 2023
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Fierloos, I.N. (author), Windhorst, D.A. (author), Fang, Y. (author), Bannink, R. (author), Stam, M. (author), Slijkerman, C.A.A. (author), Jansen, W. (author), Raat, H. (author)Aim: This study examined the association between social support perceived by parents of children aged 1–7 years and the use of additional community youth health care services. Methods: Data of 749 parents of children aged 1–7 years, gathered in the CIKEO cohort study in the Netherlands, were analyzed. Social support was assessed with the...article 2022
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Bongers, C.C.W.G. (author), de Korte, J.Q. (author), Zwartkruis, M. (author), Levels, K. (author), Kingma, B.R.M. (author), Eijsvogels, T.M.H. (author)The combination of an exacerbated workload and impermeable nature of the personal protective equipment (PPE) worn by COVID-19 healthcare workers increases heat strain. We aimed to compare the prevalence of heat strain symptoms before (routine care without PPE) versus during the COVID-19 pandemic (COVID-19 care with PPE), identify risk factors...article 2022
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Kocevska, D. (author), Lysen, T.S. (author), Dotinga, A. (author), Koopman-Verhoeff, M.E. (author), Luijk, M.P.C.M. (author), Antypa, N. (author), Biermasz, N.R. (author), Blokstra, A. (author), Brug, J. (author), Burk, W.J. (author), Comijs, H.C. (author), Corpeleijn, E. (author), Dashti, H.S. (author), de Bruin, E.J. (author), de Graaf, R. (author), Derks, I.P.M. (author), Dewald-Kaufmann, J.F. (author), Elders, P.J.M. (author), Gemke, R.J.B.J. (author), Grievink, L. (author), Hale, L. (author), Hartman, C.A. (author), Heijnen, C.J. (author), Huisman, M. (author), Huss, A. (author), Ikram, M.A. (author), Jones, S.E. (author), Klein Velderman, M. (author), Koning, M. (author), Meijer, A.M. (author), Meijer, K. (author), Noordam, R. (author), Oldehinkel, A.J. (author), Groeniger, J.O. (author), Penninx, B.W.J.H. (author), Picavet, H.S.J. (author), Pieters, S. (author), Reijneveld, S.A. (author), Reitz, E. (author), Renders, C.M. (author), Rodenburg, G. (author), Rutters, F. (author), Smith, M.C. (author), Singh, A.S. (author), Snijder, M.B. (author), Stronks, K. (author), ten Have, M, (author), Twisk, J.W.R. (author), van de Mheen, D. (author), van der Ende, J. (author), van der Heijden, K.B. (author), van der Velden, P.G. (author), van Lenthe, F.J. (author), van Litsenburg, R.R.L (author), van Oostrom, S.H. (author), van Schalkwijk, F.J. (author), Sheehan, CM, (author), Verheij, RA, (author), Verhulst, F.C. (author), Vermeulen, M.C.M. (author), Vermeulen, R.C.H. (author), Verschuren, W.M.M. (author), Vrijkotte, T.G.M. (author), Wijga, A.H. (author), Willemen, A.M. (author), ter Wolbeek, M. (author), Wood, A.R. (author), Xerxa, Y. (author), Bramer, W.M. (author), Franco, O.H. (author), Luik, A.I. (author), van Someren, E.J.W. (author), Tiemeier, H. (author)We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were identified through systematic literature search in Embase, Medline and Web of Science (9 August 2019) and through personal contacts. Eligible studies had to be...article 2021
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Kim, C. (author), Colborn, K. (author), van Buuren, S. (author), Loar, T. (author), Stevens-Lapsley, J.E. (author), Kittelson, A.J. (author)The purpose of this study was to develop and test personalized predictions for functional recovery after Total Knee Arthroplasty (TKA) surgery, using a novel neighbors-based prediction approach. We used data from 397 patients with TKA to develop the prediction methodology and then tested the predictions in a temporally distinct sample of 202...article 2021
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Regeer, H. (author), Nieuwenhuijse, E.A. (author), Vos, R.C. (author), Kiefte-de Jong, J.C. (author), van Empelen, P. (author), de Koning, E.J.P. (author), Bilo, H.J.G. (author), Huisman, S.D. (author)Aims: To investigate changes in physical activity (PA) and psychological factors during societal lockdown in people with type 2 diabetes. Methods: A cross-sectional study among Dutch adults with type 2 diabetes. Data were collected using online questionnaires. A multivariate multinomial logistic regression was performed with change in PA during...article 2021
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van den Dries, M.A. (author), Lamballais, S. (author), El Marroun, H. (author), Pronk, A. (author), Spaan, S. (author), Ferguson, K.K. (author), Longnecker, M.P. (author), Tiemeier, H. (author), Guxens, M. (author)Background: Prenatal exposure to organophosphate (OP) pesticides associate with impaired neurodevelopment in humans and animal models. However, much uncertainty exists about the brain structural alterations underlying these associations. The objective of this study was to determine whether maternal OP pesticide metabolite concentrations in urine...article 2020
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Liu, Y. (author), Toet, A. (author), Krone, T. (author), van Stokkum, R. (author), Eijsman, S. (author), van Erp, J.B.F. (author)The affective appraisal of odors is known to depend on their intensity (I), familiarity (F), detection threshold (T), and on the baseline affective state of the observer. However, the exact nature of these relations is still largely unknown. We therefore performed an observer experiment in which participants (N = 52) smelled 40 different odors ...article 2020
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Stroek, K. (author), Heijboer, A.C. (author), Bouva, M.J. (author), van der Ploeg, C.P.B. (author), Heijnen, M.L.A. (author), Weijman, G. (author), Bosch, A.M. (author), de Jonge, R. (author), Schielen, P.C.J.I. (author), van Trotsenburg, A.S.P. (author), Boelen, A. (author)Objective: Congenital hypothyroidism (CH) is defined as thyroid hormone deficiency at birth due to disorders of the thyroid gland (thyroidal CH, CH-T), or the hypothalamus or pituitary (central CH, CH-C). The Dutch Newborn Screening (NBS) strategy is primarily based on determination of thyroxine (T4) concentrations in dried blood spots followed,...article 2020
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van den Dries, M.A. (author), Guxens, M. (author), Spaan, S. (author), Ferguson, K.K. (author), Philips, E. (author), Santos, S. (author), Jaddoe, V.W.V. (author), Ghassabian, A. (author), Trasande, L. (author), Tiemeier, H. (author), Pronk, A. (author)BACKGROUND: Prenatal exposures to phthalates and bisphenols are associated with impaired brain development in animals. However, epidemiological studies investigating the association between prenatal phthalate or bisphenol exposure and cognition have produced mixed findings and mostly had modest sample sizes and measured the exposure during the...article 2020
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Michaud, P.A. (author), Visser, A. (author), Vervoort, J.P.M. (author), Kocken, P. (author), Reijneveld, S.A. (author), Blair, M. (author), Rigby, M. (author), Weber, M. (author), Jansen, D. (author)Background and objectives Adolescent sexual and reproductive health and rights (SRHR) are of particular relevance given their potential short-term or long-term health consequences. This study evaluates recommendations and policies regarding access to care in this area in 31 European countries (European Union (EU) plus Iceland, Norway and...article 2020
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Hendriks, H. (author), van de Rest, O. (author), Snippe, A. (author), Kieboom, J. (author), Hogenelst, K. (author)Long-term alcohol abuse is associated with poorer cognitive performance. However, the associations between light and moderate drinking and cognitive performance are less clear. We assessed this association via cross-sectional and longitudinal analyses in a sample of 702 Dutch students. At baseline, alcohol consumption was assessed using...article 2020
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Coenen, P. (author), Hulsegge, G. (author), Daams, J.G. (author), van Geenen, R.G. (author), Kerkhoffs, G.M. (author), van Tulder, M.W. (author), Huirne, J.A. (author), Anema, J.R. (author), Kuijser, P.P. (author)Objectives Orthopaedic surgery is primarily aimed at improving function and pain reduction. Additional integrated care may enhance patient’s participation in sports and work, possibly improving performance of physical activities and quality of life (QoL). We aimed to assess the effectiveness of integrated care among orthopaedic surgery patients....article 2020
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Offerhaus, P. (author), Jans, S (author), Hukkelhoven, C. (author), de Vries, R. (author), Nieuwenhuijze, M. (author)Background: The maternity care system in the Netherlands is well known for its support of community-based midwifery. However, regular midwifery practices typically do not offer caseload midwifery care - one-to-one continuity of care throughout pregnancy and birth. Because we know very little about the outcomes for women receiving caseload care...article 2020
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Coenen, P. (author), Robroek, S.J.W. (author), van der Beek, A.J. (author), Boot, C.R.L. (author), van Lenthe, F.J. (author), Burdorf, A. (author), Oude Hengel, K.M. (author)Background: This individual patient data (IPD) meta-analysis aimed to investigate socioeconomic inequalities in effectiveness on healthy behavior of, and compliance to, workplace health promotion programs. Methods: Dutch (randomized) controlled trials were identified and original IPD were retrieved and harmonized. A two-stage meta-analysis was...article 2020
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Schoen, E.D. (author), Wopereis, S. (author)BACKGROUND: Parallel intervention studies involving volunteers usually require a procedure to allocate the subjects to study-arms. Statistical models to evaluate the different outcomes of the study-arms will include study-arm as a factor along with any covariate that might affect the results. To ensure that the effects of the covariates are...article 2020
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Hoevenaars, F.P.M. (author), Berendsen, C.M.M. (author), Pasman, W.J. (author), van den Broek, T.J. (author), Barrat, E. (author), de Hoogh, I.M. (author), Wopereis, S. (author)In public health initiatives, generic nutrition advice (GNA) from national guidelines has a limited effect on food-intake improvement. Personalized nutrition advice (PNA) may enable dietary behavior change. A monocentric, randomized, parallel, controlled clinical trial was performed in males (n = 55) and females (n = 100) aged 25 to 70 years....article 2020