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LaCroix, G. (author), Koch, W. (author), Ritter, D. (author), Gutleb, A.C. (author), Larsen, S.T. (author), Loret, T. (author), Zanetti, F. (author), Constant, S. (author), Chortarea, S. (author), Rothen-Rutishauser, B. (author), Hiemstra, P.S. (author), Frejafan, E. (author), Hubert, P. (author), Gribaldo, L. (author), Kearns, P. (author), Aublant, J.M. (author), Diabaté, S. (author), Weiss, C. (author), de Groot, A. (author), Kooter, I.M. (author)
In vitro air–liquid interface (ALI) cell culture models can potentially be used to assess inhalation toxicology endpoints and are usually considered, in terms of relevancy, between classic (i.e., submerged) in vitro models and animal-based models. In some situations that need to be clearly defined, ALI methods may represent a complement or an...
article 2018
document
Jedynska, A. (author), Hoek, G. (author), Wang, M. (author), Yang, A. (author), Eeftens, M. (author), Cyrys, J. (author), Keuken, M. (author), Ampe, C. (author), Beelen, R. (author), Cesaroni, G. (author), Forastiere, F. (author), Cirach, M. (author), de Hoogh, K. (author), de Nazelle, A. (author), Nystad, W. (author), Akhlaghi, H.M. (author), Declercq, C. (author), Stempfelet, M. (author), Eriksen, K.T. (author), Dimakopoulou, K. (author), Lanki, T. (author), Meliefste, K. (author), Nieuwenhuijsen, M. (author), Yli-Tuomi, T. (author), Raaschou-Nielsen, O. (author), Janssen, N.A.H. (author), Brunekreef, B. (author), Kooter, I.M. (author)
Oxidative potential (OP) has been suggested as a health-relevant measure of air pollution. Little information is available about OP spatial variation and the possibility to model its spatial variability. Our aim was to measure the spatial variation of OP within and between 10 European study areas. The second aim was to develop land use...
article 2017
document
Kooter, I.M. (author), Grollers-Mulderij, M. (author), Duistermaat, E. (author), Kuper, C.F. (author)
Mucilair 3D bronchial airway models, cultured at an air-liquid interface, were exposed to aerosols of copper oxide (CuO) nanoparticles in Vitrocell air exposure modules. Four cell donors, four exposure modules and four exposure concentrations were varied within four different exposure sessions using a statistical experimental design called a...
article 2017
document
Zarcone, M.C. (author), van Schadewijk, A. (author), Duistermaat, E. (author), Hiemstra, P.S. (author), Kooter, I.M. (author)
Background: Exacerbations constitute a major cause of morbidity and mortality in patients suffering from chronic obstructive pulmonary disease (COPD). Both bacterial infections, such as those with non-typeable Haemophilus influenzae (NTHi), and exposures to diesel engine emissions are known to contribute to exacerbations in COPD patients....
article 2017
document
Pedersen, M. (author), Gehring, U. (author), Beelen, R. (author), Wang, M. (author), Giorgis-Allemand, L. (author), Andersen, A.M.N. (author), Basagaña, X. (author), Bernard, C. (author), Cirach, M. (author), Forastiere, F. (author), de Hoogh, K. (author), Gražuleviĉvienė, R. (author), Gruzieva, O. (author), Hoek, G. (author), Jedynska, A. (author), Klümper, C. (author), Kooter, I.M. (author), Krämer, U. (author), Kukkonen, J. (author), Porta, D. (author), Postma, D.S. (author), Raaschou-Nielsen, O. (author), van Rossem, L. (author), Sunyer, J. (author), Sørensen, M. (author), Tsai, M.Y. (author), Vrijkotte, T.G.M. (author), Wilhelm, M. (author), Nieuwenhuijsen, M.J. (author), Pershagen, G. (author), Brunekreef, B. (author), Kogevinas, M. (author), Slama, R. (author)
Background: The health effects of suspended particulate matter (PM) may depend on its chemical composition. Associations between maternal exposure to chemical constituents of PM and newborn’s size have been little examined. Objective: We aimed to investigate the associations of exposure to elemental constituents of PM with term low birth weight ...
article 2016
document
Mutlu, E. (author), Warren, S.H. (author), Ebersviller, S.M. (author), Kooter, I.M. (author), Schmid, J.E. (author), Dye, J.A. (author), Linak, W.P. (author), Gilmour, M.I. (author), Jetter, J.J. (author), Higuchi, M. (author), DeMarini, D.M. (author)
Background: Emissions from solid fuels used for cooking cause ~4 million premature deaths
article 2016
document
Jedynska, A.D. (author), Tromp, P.C. (author), Houtzager, M.M.G. (author), Kooter, I.M. (author)
Use of biodiesel is increasing following implementation of various policy instruments and a surge in demand due to growing urbanized populations. A series of experiments to characterize the chemical composition of emissions generated during combustion of petro-diesel (B0), biodiesel blends (B5, B10, B20), biodiesel (B100) and pure plant oil were...
article 2015
document
Beelen, R. (author), Hoek, G. (author), Raaschou-Nielsen, O. (author), Stafoggia, M. (author), Andersen, Z.J. (author), Weinmayr, G. (author), Hoffmann, B. (author), Wolf, K. (author), Samoli, E. (author), Fischer, P.H. (author), Nieuwenhuijsen, M.J. (author), Xun, W.W. (author), Katsouyanni, K. (author), Dimakopoulou, K. (author), Marcon, A. (author), Vartiainen, E. (author), Lanki, T. (author), Yli-Tuomi, T. (author), Oftedal, B. (author), Schwarze, P.E. (author), Nafstad, P. (author), de Faire, U. (author), Pedersen, N.L. (author), Östenson, C.-G. (author), Fratiglioni, L. (author), Penell, J. (author), Korek, M. (author), Pershagen, G. (author), Eriksen, K.T. (author), Overvad, K. (author), Sørensen, M. (author), Eeftens, M. (author), Peeters, P.H. (author), Meliefste, K. (author), Wang, M. (author), Bas Bueno-De-Mesquita, H. (author), Sugiri, D. (author), Krämer, U. (author), Heinrich, J. (author), De Hoogh, K. (author), Key, T. (author), Peters, A. (author), Hampel, R. (author), Concin, H. (author), Nagel, G. (author), Jaensch, A. (author), Ineichen, A. (author), Tsai, M.-Y. (author), Schaffner, E. (author), Probst-Hensch, N.M. (author), Schindler, C. (author), Ragettli, M.S. (author), Vilier, A. (author), Clavel-Chapelon, F. (author), Declercq, C. (author), Ricceri, F. (author), Sacerdote, C. (author), Galassi, C. (author), Migliore, E. (author), Ranzi, A. (author), Cesaroni, G. (author), Badaloni, C. (author), Forastiere, F. (author), Katsoulis, M. (author), Trichopoulou, A. (author), Keuken, M. (author), Jedynska, A. (author), Kooter, I.M. (author), Kukkonen, J. (author), Sokhi, R.S. (author), Vineis, P. (author), Brunekreef, B. (author)
Background: Studies have shown associations between mortality and long-term exposure to particulate matter air pollution. Few cohort studies have estimated the effects of the elemental composition of particulate matter on mortality. oBjectives: Our aim was to study the association between natural-cause mortality and long-term exposure to...
article 2015
document
Gerlofs-Nijland, N.E. (author), Vercruijsse, W. (author), Cassee, F.R. (author), Janssen, P. (author), Kadijk, G. (author), Kooter, I.M. (author), Verbeek, R.P. (author), van Zyl, P.S. (author), Jedynska, A.D. (author), Koornneef, G.P. (author)
There are no strong indications that mixing FAME (Fatty Acid Methyl Ester) biodiesel up to 7 vol%2 and HVO (Hydrotreated Vegetable Oil) biodiesel up to 30 vol% will result in significant increase in harmful emissions by road traffic. This conclusion is based on the limited toxicological data suggesting low or negligible changes in the hazard...
report 2014
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