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Dankers, A.C.A. (author), Kuper, C.F. (author), Boumeester, A.J. (author), Fabriek, B.O. (author), Kooter, I.M. (author), Gröllers-Mulderij, M. (author), Tromp, P. (author), Nelissen, I. (author), Zondervan-Van Den Beuken, E.K. (author), Vandebriel, R.J. (author)
Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled metal oxide NPs may generate inflammation. The aim of this study was to investigate the proinflammatory potential of six metal oxide NPs (CeO2, Mn2O3, CuO, ZnO, Co3O4 and WO3; 27–108 μg ml−1) using human primary 3-dimensional airway epithelium (MucilAir™)...
article 2018
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Markus, A.A. (author), Krystek, P. (author), Tromp, P.C. (author), Parsons, J.R. (author), Roex, E.W.M. (author), de Voogt, P. (author), Laane, R.W.P.M. (author)
We investigated the occurrence of metal-based nanoparticles in a natural system, the river Dommel in the Netherlands. The river itself is well-studied as far as hydrology and water quality is concerned, easily accessible and contains one major wastewater treatment plant discharging onto this river. We sampled water from various locations along...
article 2018
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Downward, G.S. (author), Hu, W. (author), Rothman, N. (author), Reiss, B. (author), Tromp, P. (author), Wu, G. (author), Wei, F. (author), Xu, J. (author), Seow, W.J. (author), Chapman, R.S. (author), Lan, Q. (author), Vermeulen, R. (author)
Exposure to crystalline silica (quartz) has been implicated as a potential cause of the high lung cancer rates in the neighbouring counties of Xuanwei and Fuyuan, China, where the domestic combustion of locally sourced “smoky” coal (a bituminous coal) is responsible for some of the highest lung cancer rates in the nation, irrespective of gender...
article 2017
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Gallocchio, F. (author), Biancotto, G. (author), Cibin, V. (author), Losasso, C. (author), Belluco, S. (author), Peters, R. (author), van Bemmel, G. (author), Cascio, C. (author), Weigel, S. (author), Tromp, P. (author), Gobbo, F. (author), Catania, S. (author), Ricci, A. (author)
Silver nanoparticles (AgNPs) are of interest due to their antimicrobial activity and are seen as potential candidates to replace antibiotics in animal husbandry. A few studies have focused on this new application, but they lack any considerations about residual accumulation of AgNPs in edible animal tissues and animal products. In this research,...
article 2017
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Spaan, S. (author), Schinkel, J. (author), Tromp, P. (author)
report 2017
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Schinkel, J.M. (author), den Boeft, J. (author), Tromp, P.C. (author), de Jonge, M. (author)
Deze rapportage beschrijft een gesimuleerd werkplek beschermingsfactor (SWPF)
report 2017
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Spaan, S. (author), Tromp, P. (author), Diks, M. (author), Krystek, P. (author), Schinkel, J. (author)
report 2017
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Helsper, J.P.F.G. (author), Peters, R.J.B. (author), van Bemmel, M.E.M. (author), Rivera, Z.E.H. (author), Wagner, S. (author), von der Kammer, F. (author), Tromp, P.C. (author), Hofmann, T. (author), Weigel, S. (author)
Seven commercial titanium dioxide pigments and two other well-defined TiO2 materials (TiMs) were physicochemically characterised using asymmetric flow field flow fractionation (aF4) for separation, various techniques to determine size distribution and inductively coupled plasma mass spectrometry (ICPMS) for chemical characterization. The aF4...
article 2016
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Spaan, S. (author), Voogd, E. (author), Tromp, P.C. (author), den Boeft, J. (author), de Jong, R. (author), Diks, M.V. (author), Schinkel, J.M. (author)
Naar aanleiding van de (op handen zijnde) verlaging van de grenswaarde voor asbest is binnen het Kennisinvesteringsproject (KIP) “Innovaties voor veilig werken met asbest” een van de doelstellingen om de onderliggende meetgegevens van het huidige SMA-rt systeem opnieuw te evalueren, als opmaat voor de verdere ontwikkeling van dit systeem....
report 2016
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Tromp, P.C. (author)
Inleiding en doelstelling Sinds 1978 is asbestbeleid ontwikkeld en uitgevoerd, gericht op het terugdringen van het voorkomen van asbest in enigerlei vorm in het binnen- en buitenmilieu. Het is te verwachten dat vooral het verbod op asbesthoudende remvoeringen en het sluiten van de asbest verwerkende industrie tot een aanzienlijke reductie van de...
report 2016
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Kooter, I.M. (author), Grollers-Mulderij, M. (author), Steenhof, M. (author), Duistermaat, E. (author), van Acker, F.A.A. (author), Staal, Y.C.M. (author), Tromp, P.C. (author), Schoen, E.D. (author), Kuiper, C.F. (author), van Someren, E.P. (author)
There is a need for representative in vitro models to assess the effects of airborne particles on lung health. The ob-jective of this study was to assess the cellular effects of cerium oxide (Ce02) particles exposed via an air—liquid interface in three relevant cell models in parallel. BEAS-2B, A549, and MucilAirTM cells were exposed for 1 hour...
article 2016
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Fransman, W. (author), Bekker, C. (author), Tromp, P. (author), Duis, W.B. (author)
Increasing production and applications of manufactured nano objects (MNOs) have become a source for human exposure and therefore raise concerns and questions about the possible health effects. In this study, the potential release of nano objects, their agglomerates, and aggregates (NOAA) as a result of sanding of hardwood treated with MNOs...
article 2016
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Spaan, S. (author), den Boeft, K. (author), Tromp, P. (author), Tempelman, J. (author), Schinkel, J. (author)
report 2016
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Tromp, P.C. (author), Tempelman, J. (author)
report 2016
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Keuken, M. (author), Moerman, M.M. (author), Tromp, P.C. (author)
Naar aanleiding van onderzoek door TNO in 2014 heeft het Ministerie van I&M aan het RIVM gevraagd de ultrafijn stof niveaus rondom Schiphol in 2015 te onderzoeken. Als onderdeel van dit onderzoek heeft het RIVM aan het ECN opdracht gegeven om metingen uit te voeren. Vervolgens heeft het ECN aan TNO gevraagd de eerder uitgevoerde metingen op de...
report 2015
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Walczak, A.P. (author), Kramer, E. (author), Hendriksen, P.J.M. (author), Tromp, P. (author), Helsper, J.P.F.G. (author), van der Zande, M. (author), Rietjens, I.M.C.M. (author), Bouwmeester, H. (author)
Intestinal translocation is a key factor for determining bioavailability of nanoparticles (NPs) after oral uptake. Therefore, we evaluated three in vitro intestinal cell models of increasing complexity which might affect the translocation of NPs: a mono-culture (Caco-2 cells), a co-culture with mucus secreting HT29-MTX cells and a tri-culture...
article 2015
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Jedynska, A.D. (author), Tromp, P.C. (author), Houtzager, M.M.G. (author), Kooter, I.M. (author)
Use of biodiesel is increasing following implementation of various policy instruments and a surge in demand due to growing urbanized populations. A series of experiments to characterize the chemical composition of emissions generated during combustion of petro-diesel (B0), biodiesel blends (B5, B10, B20), biodiesel (B100) and pure plant oil were...
article 2015
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Kloet, S.K. (author), Walczak, A.P. (author), Louisse, J. (author), van den Berg, H.H.J. (author), Bouwmeester, H. (author), Tromp, P. (author), Fokkink, R.G. (author), Rietjens, I.M.C.M. (author)
To obtain insight in translocation of nanoparticles across the placental barrier, translocation was studied for one positively and two negatively charged polystyrene nanoparticles (PS-NPs) of similar size in an in vitro model. The model consisted of BeWo b30 cells, derived from a human choriocarcinoma grown on a transwell insert forming a cell...
article 2015
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van der Ploeg, M.J.C. (author), Handy, R.D. (author), Waalewijn-Kool, P.L. (author), van den Berg, J.H.J. (author), Herrera Rivera, Z.E. (author), Bovenschen, J. (author), Molleman, B. (author), Baveco, J.M. (author), Tromp, P. (author), Peters, R.J.B. (author), Koopmans, G.F. (author), Rietjens, I.M.C.M. (author), van den Brink, N.W. (author)
The impact of silver nanoparticles (AgNP; at 0mg Ag/kg, 1.5mg Ag/kg, 15.4mg Ag/kg, and 154mg Ag/kg soil) and silver nitrate (AgNO3; 15.4mg Ag/kg soil) on earthworms, Lumbricus rubellus, was assessed. A 4-wk exposure to the highest AgNP treatment reduced growth and reproduction compared with the control. Silver nitrate (AgNO3) exposure also...
article 2014
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Peters, R.J.B. (author), van Bemmel, G. (author), Herrera-Rivera, Z. (author), Helsper, H.P.F.G. (author), Marvin, H.J.P. (author), Weigel, S. (author), Tromp, P.C. (author), Oomen, A.G. (author), Rietveld, A.G. (author), Bouwmeester, H. (author)
Titanium dioxide (TiO2) is a common food additive used to enhance the white color, brightness, and sometimes flavor of a variety of food products. In this study 7 food grade TiO2 materials (E171), 24 food products, and 3 personal care products were investigated for their TiO 2 content and the number-based size distribution of TiO2 particles...
article 2014
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