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Hopman-Rock, M. (author), Westhoff, M.H. (author)
In order to promote health in people of 65 years and older, TNO Prevention and Health developed, evaluated, and implemented "Healthy & Vital" (also known as "Ageing Well and Healthily"). Healthy & Vital consists of six sessions of health education and low-intensity exercises. This paper reports on the theoretical basis of the intervention, the...
article 2002
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Meulenbelt, I. (author), Bijkerk, C. (author), Miedema, H.S. (author), Breedveld, F.C. (author), Hofman, A. (author), Valkenburg, H.A. (author), Pols, H.A.P. (author), Slagboom, P.E. (author), van Duijn, C.M. (author), Gaubius Instituut TNO (author)
Objective - A genetic association study was performed to investigate whether radiographical osteoarthritis (ROA) was associated with specific genotypes of the insulin-like growth factor I (IGF-1) gene. Methods - Subjects aged 55-65 years were selected from a population-based study of which ROA at the knee, hip, spine, and hand was assessed....
article 1998
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van den Hurk, K. (author), van Dommelen, P. (author), van Buuren, S. (author), Verkerk, P.H. (author), HiraSing, R.A. (author), TNO Kwaliteit van Leven (author)
Objective: To assess the prevalence of overweight and obesity in children living in the Netherlands and compare the findings with the Third and Fourth National Growth Studies carried out in 1980 and 1997, respectively. Design and methods: Data were obtained from the child health care system. International cut-off points for body mass index (BMI)...
article 2007
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Borghi, E. (author), de Onis, M. (author), Garza, C. (author), van den Broeck, J. (author), Frongillo, E.A. (author), Grummer-Strawn, L. (author), van Buuren, S. (author), Pan, H. (author), Molinari, L. (author), Martorell, R. (author), Onyango, A.W. (author), Martines, J.C. (author), Pinol, A. (author), Siyam, A. (author), Victoria, C.G. (author), Bhan, M.K. (author), Araújo, C.L. (author), Lartey, A. (author), Owusu, W.B. (author), Bhandari, N. (author), Norum, K.R. (author), Bjoerneboe, G.-E.Aa. (author), Mohamed, A.J. (author), Dewey, K.G. (author), Belbase, K. (author), Chumlea, C. (author), Cole, T. (author), Shrimpton, R. (author), Albernaz, E. (author), Tomasi, E. (author), de Cássia Fossati da Silveira, R. (author), Nader, G. (author), Sagoe-Moses, I. (author), Gomez, V. (author), Sagoe-Moses, C. (author), Taneja, S. (author), Rongsen, T. (author), Chetia, J. (author), Sharma, P. (author), Bahl, R. (author), Baerug, A. (author), Tufte, E. (author), Alasfoor, D. (author), Prakash, N.S. (author), Mabry, R.M. (author), Al Rajab, H.J. (author), Helmi, S.A. (author), Nommsen-Rivers, L.A. (author), Cohen, R.J. (author), Heinig, M.J. (author), TNO Kwaliteit van Leven (author)
The World Health Organization (WHO), in collaboration with a number of research institutions worldwide, is developing new child growth standards. As part of a broad consultative process for selecting the best statistical methods, WHO convened a group of statisticians and child growth experts to review available methods, develop a strategy for...
article 2006
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Verhage, B.A.J. (author), Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Using data collected of a large population-based cohort study, we studied the association between anthropometric factors and the risk of pancreatic cancer. Furthermore, we investigated whether these associations differ among microscopically confirmed pancreatic cancer (MCPC) cases and non-MCPC (NMCPC) cases. The Netherlands Cohort Study on Diet...
article 2007
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Beulens, J.W.J. (author), de Zoete, E.C. (author), Kok, F.J. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Objective: Moderate alcohol consumption is associated with a decreased risk of type II diabetes. This study investigates the effect of moderate alcohol consumption on adipokines and insulin sensitivity. Subjects: Twenty healthy, lean (body mass index (BMI) 18.5-25 kg/m2; n=11) or overweight (BMI>27 kg/m2; n=9) men (18-25 years). Methods: Three...
article 2008
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de Kroon, M.L.A. (author), Renders, C.M. (author), Kuipers, E.C.C. (author), van Wouwe, J.P. (author), van Buuren, S. (author), de Jonge, G.A. (author), Hirasing, R.A. (author), TNO Kwaliteit van Leven (author)
Background: Within the context of the obesity epidemic identifying young adults at risk for type 2 diabetes and cardiovascular disease is important. A practical approach is based on the identification of metabolic syndrome (MetS). Our objective was to develop a simple and efficient stepwise strategy to identify MetS in young adults. Methods:...
article 2008
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Sierksma, A. (author), Patel, H. (author), Ouchi, N. (author), Kihara, S. (author), Funahashi, T. (author), Heine, R.J. (author), Grobbee, D.E. (author), Kluft, C. (author), Hendriks, H.F.J. (author), TNO Preventie en Gezondheid (author)
OBJECTIVE - Epidemiological studies suggest that moderate alcohol consumers have enhanced insulin sensitivity and a reduced risk of type 2 diabetes. Adiponectin, an adipocyte-derived plasma protein, has been found to be negatively associated with adiposity and positively associated with insulin sensitivity. Moderate alcohol consumption may...
article 2004
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Agyemang, C. (author), Owusu-Dabo, E. (author), de Jonge, A. (author), Martins, D. (author), Ogedegbe, G. (author), Stronks, K. (author), TNO Kwaliteit van Leven (author)
Objective: To investigate differences in overweight and obesity between first-generation Dutch-Ghanaian migrants in The Netherlands and their rural and urban counterparts in Ghana. Design: Cross-sectional study. Subjects: A total of 1471 Ghanaians (rural Ghanaians, n 532; urban Ghanaians, n 787; Dutch-Ghanaians, n 152) aged ≥17 years. Main...
article 2009
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van Dommelen, P. (author), de Gunst, M.C.M. (author), van der Vaart, A.W. (author), van Buuren, S. (author), Boomsma, D.I. (author), TNO Preventie en Gezondheid (author)
Objective. To determine the magnitude of the growth retardation in Dutch monozygotic and dizygotic twins during infancy in comparison with the Dutch reference growth charts for general population infants from 1997 and to construct reference growth charts for twins. Design. Descriptive. Method. The growth of twins was studied using longitudinal...
article 2004
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Dousma, M. (author), Wierdsma, N. (author), van Ede, J. (author), van Buuren, S. (author), Heijmans, H.S.A. (author), de Vries, T.W. (author), TNO Kwaliteit van Leven (author)
article 2007
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Eijkemans, M. (author), Mommers, M. (author), de Vries, S.I. (author), van Buuren, S. (author), Stafleu, A. (author), Bakker, I. (author), Thijs, C. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. Prevalence of asthma and overweight has increased simultaneously during the past decades. Several studies have reported an association between these two health problems, but it is unclear whether this relation is causal. We hypothesize that children with asthmatic symptoms are less physically active, which may contribute to the...
article 2008
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Beulens, J.W.J. (author), Rimm, E.B. (author), Ascherio, A. (author), Spiegelman, D. (author), Hendriks, H.F.J. (author), Mukamal, K.J. (author), TNO Kwaliteit van Leven (author)
Background: Heavy alcohol consumption increases risk for hypertension, which is in itself a strong risk factor for cardiovascular disease (CVD). However, data on the association between alcohol consumption and CVD among individuals with hypertension are scarce. Objective: To assess whether alcohol consumption is inversely associated with CVD...
article 2007
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Stein, A.D. (author), Kahn, H.S. (author), Rundle, A. (author), Zybert, P.A. (author), van der Pal-de Bruin, K.M. (author), Lumey, L.H. (author), TNO Kwaliteit van Leven (author)
Background: Few studies in humans have related maternal undernutrition to the size of the adult offspring. Objective: The objective was to assess whether reductions in food intake by pregnant women during the Dutch famine of 1944-1945 were related to offspring length, weight, and indexes of adiposity in middle age. Design: We recruited 1)...
article 2007
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Merry, A.H.H. (author), Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Background: In the last decades, the incidence of oesophageal and gastric cardia adenocarcinoma has increased rapidly in the Western world. We investigated the association between body mass index (BMI), height and risk of oesophageal and gastric cardia adenocarcinoma. Methods: The Netherlands Cohort Study was initiated in 1986. All participants ...
article 2007
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Bemelmans, W.J.E. (author), Broer, J. (author), Hulshof, K.F.A.M. (author), Siero, F.W. (author), May, J.F. (author), Meyboom-de Jong, B. (author), TNO Voeding (author)
Background: Treatment of persons at high risk for coronary heart disease (CHD) should include nutritional counselling, but little is known about the effects of different types of education. Methods: In a quasi-experimental study design the effects of a nutritional education programme (1st year: three group sessions by a dietitian; 2nd year: one...
article 2004
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Jans, M.P. (author), van den Heuvel, S.G. (author), Hildebrandt, V.H. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE: To determine the relation between body mass index (BMI) and absenteeism. METHODS: Data were collected in a prospective cohort study (n = 1284). Multilevel analyses (linear mixed model with random intercept) with two levels (employee and company) were used to test whether BMI was related to duration and frequency of absenteeism and...
article 2007
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Brugman, E. (author), Meulmeester, J.F. (author), van der Spee-Wekke, A. (author), Beuker, R.J. (author), Zaadstra, B.M. (author), Radder, J.J. (author), Verloove-Vanhorick, P.S. (author), TNO Preventie en Gezondheid (author)
OBJECTIVE: To estimate the prevalence of dieting and the relationship between dieting, nutritional habits, and health among young adolescents in the Netherlands. METHODS: Out of 1359 secondary school children, aged 13 through 15 y, who were invited for a routine health assessment by school doctors or nurses as part of the Child Health Monitoring...
article 1997
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Fredriks, A.M. (author), van Buuren, S. (author), Fekkes, M. (author), Verloove-Vanhorick, S.P. (author), Wit, J.M. (author)
The aim of this study was to present age references for waist circumference (WC), hip circumference (HC), and waist/hip ratio (WHR) in Dutch children. Cross-sectional data were obtained from 14,500 children of Dutch origin in the age range 0-21 years. National references were constructed with the LMS method. This method summarises the...
article 2005
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van Buuren, S. (author), TNO Preventie en Gezondheid (author)
Objective. To determine the cut-off values for the body-mass index (BMI) for underweight and serious underweight in children up to 18 years of age based on the Dutch growth standards of 1980, and to determine the prevalence of underweight and serious underweight in the 1997 Dutch growth-study figures. Design. Secondary data analysis. Method. Cut...
article 2004
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