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Velthuis-te Wierik, E.J.M. (author), Meijer, P. (author), Kluft, C. (author), van den Berg, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Impaired fibrinolytic activity has been reported in the elderly and is thought to play a role in the etiology of cardiovascular disease, one of the leading causes of death in most Western countries. Since restriction of energy intake has been demonstrated to act beneficially on the aging process in a variety of species, we studied the effect of...
article 1995
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te Velthuis- Wierik, E.J.M. (author), van den Berg, H. (author), Weststrate, J.A. (author), van het Hof, K.H. (author), de Graaf, C. (author), TNO Voeding (author)
Objective: Dietary fat intake is higher than recommended in most western countries and is associated with the prevalence of cardiovascular diseases, obesity and cancer. The growing public concern about the adverse effects of a high fat intake has led to an increased availability of 'reduced-fat' products. Consumption of reduced-fat products...
article 1996
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van den Brandt, P.A. (author), Dirx, M.J.M. (author), Ronckers, C.M. (author), van den Hoogen, P. (author), Goldbohm, R.A. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
The association between several anthropometric indices and breast cancer risk was evaluated within the Netherlands Cohort Study on diet and cancer, which began in 1986 and is conducted among 62,573 women aged 55 to 69 years at baseline. After 4.3 years of follow-up, data on 626 women with incident breast cancer were available with complete...
article 1997
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Pasman, W.J. (author), Saris, W.H.M. (author), Westerterp-Plantenga, M.S. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To obtain predictors of weight maintenance after a weight-loss intervention. Research Methods and Procedures: An overall analysis of data from two-long intervention studies [n = 67 women; age: 37.9±1.0 years; body weight (BW): 87.0±1.2 kg; body mass index: 32.1±0.5 kg·m-2; % body fat: 42.4±0.5%]. Subjects were measured before a very...
article 1999
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Schuurman, A.G. (author), Goldbohm, R.A. (author), Dorant, E. (author), van den Brandt, P.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In the Netherlands Cohort Study, the authors investigated whether anthropometry is associated with prostate cancer risk. At baseline in 1986, 58,279 men aged 55-69 years completed a self- administered questionnaire on diet, anthropometry, and other risk factors for cancer. After 6.3 years of follow-up, 681 cases were available with complete data...
article 2000
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Broekmans, W.M.R. (author), Klöpping-Ketelaars, I.A.A. (author), Schuurman, C.R.W.C. (author), Verhagen, H. (author), van den Berg, H. (author), Kok, F.J. (author), van Poppel, G. (author), TNO Voeding (author)
Observational epidemiologic studies have shown that a high consumption of fruits and vegetables is associated with a decreased risk of chronic diseases. Little is known about the bioavailability of constituents from vegetables and fruits and the effect of these constituents on markers for disease risk. Currently, the recommendation is to...
article 2000
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Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author)
Although many studies have been conducted to investigate the relation between anthropometry and the risk of ovarian cancer, their results have been inconsistent. The Netherlands Cohort Study on Diet and Cancer was initiated in 1986. A self-administered questionnaire on dietary habits and other risk factors for cancer was completed by 62,573...
article 2003
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Fredriks, A.M. (author), van Buuren, S. (author), Jeurissen, S.E.R. (author), Dekker, F.W. (author), Verloove-Vanhorick, S.P. (author), Wit, J.M. (author)
The aim of this study was to provide growth and sexual maturation reference data for Turkish children living in The Netherlands. We also compared these references with the reference data of children of Dutch origin and with Turkish reference data collected in Turkey and elsewhere in Europe. Cross-sectional growth and demographic data were...
article 2003
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Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
Although obesity is an established risk factor for endometrial cancer, evidence linking risk to height, weight change since age 20, and physical activity is limited. In this case-cohort study, 62 573 women from The Netherlands Cohort Study on Diet and Cancer were followed up from 1986 to 1995, and 226 endometrial cancer case patients were...
article 2004
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Sierksma, A. (author), Patel, H. (author), Ouchi, N. (author), Kihara, S. (author), Funahashi, T. (author), Heine, R.J. (author), Grobbee, D.E. (author), Kluft, C. (author), Hendriks, H.F.J. (author), TNO Preventie en Gezondheid (author)
OBJECTIVE - Epidemiological studies suggest that moderate alcohol consumers have enhanced insulin sensitivity and a reduced risk of type 2 diabetes. Adiponectin, an adipocyte-derived plasma protein, has been found to be negatively associated with adiposity and positively associated with insulin sensitivity. Moderate alcohol consumption may...
article 2004
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van Dommelen, P. (author), de Gunst, M.C.M. (author), van der Vaart, A.W. (author), van Buuren, S. (author), Boomsma, D.I. (author), TNO Preventie en Gezondheid (author)
Objective. To determine the magnitude of the growth retardation in Dutch monozygotic and dizygotic twins during infancy in comparison with the Dutch reference growth charts for general population infants from 1997 and to construct reference growth charts for twins. Design. Descriptive. Method. The growth of twins was studied using longitudinal...
article 2004
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Bemelmans, W.J.E. (author), Broer, J. (author), Hulshof, K.F.A.M. (author), Siero, F.W. (author), May, J.F. (author), Meyboom-de Jong, B. (author), TNO Voeding (author)
Background: Treatment of persons at high risk for coronary heart disease (CHD) should include nutritional counselling, but little is known about the effects of different types of education. Methods: In a quasi-experimental study design the effects of a nutritional education programme (1st year: three group sessions by a dietitian; 2nd year: one...
article 2004
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Fredriks, A.M. (author), van Buuren, S. (author), Fekkes, M. (author), Verloove-Vanhorick, S.P. (author), Wit, J.M. (author)
The aim of this study was to present age references for waist circumference (WC), hip circumference (HC), and waist/hip ratio (WHR) in Dutch children. Cross-sectional data were obtained from 14,500 children of Dutch origin in the age range 0-21 years. National references were constructed with the LMS method. This method summarises the...
article 2005
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Borghi, E. (author), de Onis, M. (author), Garza, C. (author), van den Broeck, J. (author), Frongillo, E.A. (author), Grummer-Strawn, L. (author), van Buuren, S. (author), Pan, H. (author), Molinari, L. (author), Martorell, R. (author), Onyango, A.W. (author), Martines, J.C. (author), Pinol, A. (author), Siyam, A. (author), Victoria, C.G. (author), Bhan, M.K. (author), Araújo, C.L. (author), Lartey, A. (author), Owusu, W.B. (author), Bhandari, N. (author), Norum, K.R. (author), Bjoerneboe, G.-E.Aa. (author), Mohamed, A.J. (author), Dewey, K.G. (author), Belbase, K. (author), Chumlea, C. (author), Cole, T. (author), Shrimpton, R. (author), Albernaz, E. (author), Tomasi, E. (author), de Cássia Fossati da Silveira, R. (author), Nader, G. (author), Sagoe-Moses, I. (author), Gomez, V. (author), Sagoe-Moses, C. (author), Taneja, S. (author), Rongsen, T. (author), Chetia, J. (author), Sharma, P. (author), Bahl, R. (author), Baerug, A. (author), Tufte, E. (author), Alasfoor, D. (author), Prakash, N.S. (author), Mabry, R.M. (author), Al Rajab, H.J. (author), Helmi, S.A. (author), Nommsen-Rivers, L.A. (author), Cohen, R.J. (author), Heinig, M.J. (author), TNO Kwaliteit van Leven (author)
The World Health Organization (WHO), in collaboration with a number of research institutions worldwide, is developing new child growth standards. As part of a broad consultative process for selecting the best statistical methods, WHO convened a group of statisticians and child growth experts to review available methods, develop a strategy for...
article 2006
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Stein, A.D. (author), Kahn, H.S. (author), Rundle, A. (author), Zybert, P.A. (author), van der Pal-de Bruin, K.M. (author), Lumey, L.H. (author), TNO Kwaliteit van Leven (author)
Background: Few studies in humans have related maternal undernutrition to the size of the adult offspring. Objective: The objective was to assess whether reductions in food intake by pregnant women during the Dutch famine of 1944-1945 were related to offspring length, weight, and indexes of adiposity in middle age. Design: We recruited 1)...
article 2007
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TNO Kwaliteit van Leven (author), Rotteveel, J. (author), Belksma, E.J. (author), Renders, C.M. (author), Hirasing, R.A. (author), Delemarre-Van de Waal, H.A. (author)
Objective: The worldwide trend towards obesity in childhood is also observed in the Netherlands and one of the consequences may be type 2 diabetes. In this study, we assessed the number of children with type 2 diabetes, diagnosed by paediatricians, in the Netherlands. Methods: In 2003 and 2004 the Dutch Paediatric Surveillance Unit, a nationwide...
article 2007
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TNO Kwaliteit van Leven (author), Verheijden, M.W. (author), Jans, M.P. (author), Hildebrandt, V.H. (author), Hopman-Rock, M. (author)
Background: In recent years, many tailored lifestyle counseling programs have become available through the Internet. Previous research into such programs has shown selective enrollment of relatively healthy people. However, because of the known dose-response relationship between the intensity and frequency of counseling and the behavior change...
article 2007
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Beulens, J.W.J. (author), de Zoete, E.C. (author), Kok, F.J. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Objective: Moderate alcohol consumption is associated with a decreased risk of type II diabetes. This study investigates the effect of moderate alcohol consumption on adipokines and insulin sensitivity. Subjects: Twenty healthy, lean (body mass index (BMI) 18.5-25 kg/m2; n=11) or overweight (BMI>27 kg/m2; n=9) men (18-25 years). Methods: Three...
article 2008
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Hughes, L.A.E. (author), Arts, I.C.W. (author), Ambergen, T. (author), Brants, H.A.M. (author), Dagnelie, P.C. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), Weijenberg, M.P. (author), TNO Kwaliteit van Leven (author)
Background: Dietary flavonoids are suggested to have antiobesity effects. Prospective evidence of an association between flavonoids and body mass index (BMI) is lacking in general populations. Objective: We assessed this association between 3 flavonoid subgroups and BMI over a 14-y period in 4280 men and women aged 55-69 y at baseline from the...
article 2008
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van den Berg, J.F. (author), Knvistingh Neven, A. (author), Tulen, J.H.M. (author), Hofman, A. (author), Witteman, J.C.M. (author), Miedema, H.M.E. (author), Tiemeier, H. (author), TNO Bouw en Ondergrond (author)
Objective: The epidemiological evidence for the association between sleep duration and obesity in the elderly is inconsistent and has not been investigated with objective measures. Furthermore, the role of sleep fragmentation in this relationship is unknown. Our aim was to investigate the association of sleep measures with body mass index (BMI)...
article 2008
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